Cold Spring Harb Perspect Med June 2016 PMID 27252397

Aminoglycosides: An Overview.

Kevin M Krause, Alisa W Serio, Timothy R Kane, Lynn E Connolly

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Mentions

Peak: 2 in May 2024

across 3 sources since Feb 2019

Extended reach

17,084

potential audience

Total likes

180

Video views

16,482

Mentions per month

Feb 2019 – May 2024

Where it's discussed

X / Twitter2 posts
News2 articles
YouTube1 videos

AI synopsis

What people are saying

Discussions demonstrate a neutral tone with basic recognition of aminoglycosides' mechanisms and history, exemplified by comments like 'potent, broad-spectrum antibiotics' and references to their mode of action. Their tone and brevity imply a moderate level of interest and engagement, reflecting recognition rather than deep exploration of the article's broader implications.

AgreementModerate agreement

Most discussions acknowledge the validity of the publication's points about aminoglycosides' historical importance and their renewed relevance amidst antibiotic resistance.

InterestModerate interest

Participants show moderate curiosity, with comments highlighting the antibiotics' mechanisms and the potential for clinical use, but few delve deeply into detailed implications.

EngagementModerate engagement

Comments tend to be brief and somewhat cursory, such as noting that aminoglycosides inhibit protein synthesis or referencing the source, rather than engaging with complex ideas or debates.

ImpactModerate impact

The overall tone suggests that the publication informs and reinforces existing knowledge but does not appear to drastically shift opinions or practices among the participants.

Abstract in brief

Aminoglycosides are antibiotics derived from actinomycetes that were among the first used in clinical practice, initially serving as the primary choice for bacterial infections.
Although they were largely replaced by other antibiotics like cephalosporins and fluoroquinolones in the 1980s, there has been renewed interest due to their effectiveness against resistant bacteria and potential for combination therapy.
They work quickly to kill bacteria and can enhance the effects of other antibiotics, making them valuable again in modern medicine with improved dosing strategies.

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All mentions

Aminoglycosides Mechanism of Action and Clinical Significance

This video explains the mechanisms of aminoglycosides, including their inhibition of bacterial translation processes. It also discusses their historical use, current relevance against resistant bacteria, and potential…

StudyMed · Feb 16, 2019 16,482 views

Megan Elizabeth Graham

@grahamemegan · X

“Aminoglycosides are potent, broad-spectrum antibiotics that act through inhibition of protein synthesis” https://t.co/UKugjcrdVh

May 26, 2024 · 301 followers View post →