October 2016 PMID 27277934

Statin use and the risk of developing diabetes: a network meta-analysis.

Divyesh Thakker, Sunita Nair, Amit Pagada, Vinayak Jamdade, Anuradha Malik

Mentions

24
Peak: 5 in Aug 2022
across 5 sources since Jun 2021

Extended reach

265,874
potential audience

Total likes

8,711

Video views

235,244

Mentions per month

Jun 2021 – Aug 2025

Where it's discussed

  • X / Twitter16 posts
  • News4 articles
  • YouTube2 videos
  • Bluesky1 posts
  • Facebook1 posts

AI synopsis

What people are saying

The discussions reflect nuanced reactions, with some posts supporting the article’s insights and emphasizing the need to weigh benefits versus risks, such as mentions of the 'slight' risk increase or questioning conflicts of interest. Tone varies from cautious to critical, with examples like 'cherry picking' critiques and concerns about the long-term implications of statin therapy, highlighting a complex dialogue about how significant and reliable the findings are.

AgreementModerate agreement

Most discussions acknowledge the findings about statins' slight increase in diabetes risk, with some showing cautious support.

InterestHigh interest

The discussions are highly relevant to those interested in medication risks and health implications, evident in detailed critiques and discussions of the research methods.

EngagementModerate engagement

Participants engage by questioning study validity, discussing specific statins, and debating clinical implications, indicating moderate depth of involvement.

ImpactModerate impact

The discussions influence ongoing debates about statin use, risk management, and conflict of interest, suggesting a modest but meaningful impact on public and professional opinion.

Abstract in brief

  • This systematic review and network meta-analysis examined the relationship between statin use and the increased risk of developing diabetes, finding that statins as a class are associated with a small but significant rise in diabetes risk.
  • Among various statins analyzed, high-dose atorvastatin posed the highest risk for diabetes, with an odds ratio of 1.34, and other statins like rosuvastatin and low-dose atorvastatin also showed increased risk.
  • Overall, the findings suggest that more intensive statin therapy may slightly raise the likelihood of diabetes, highlighting the importance for clinicians to weigh benefits against potential risks when prescribing these medications.

Top posts

Most liked on X and Bluesky
م. محمود سعد
@Eng_mahmoudSad · X

@NedaaAlkhamis المجلة الطبيه البريطانيه لا علاقة لارتفاع الكوليسترول الشديد بالجلطات القلبيه في العوائل المصابه بFH https://t.co/KnPyTgjD8y أدويه الكوليسترول (الستاتين) تسبب السكري دراسه حديثه https://t.co/iDKaWXKzgS https://t.co/IWJXaMOfMt إدارة الغذاء والدواء FDA https://t.co/ExWzzCzq9U

Aug 7, 2023 · 14 likes · 3 shares · 1,009 followers View post →
ZKForTre
@ZKForTre · X

Your predilection for cherry picking individual studies where robust meta analyses are readily available is beyond perplexing. It’s more like 12% for high-intensity statin regimens. Decreases down to 0 excess risk with moderate intensity ones. https://t.co/W2d8z0EUBS https://t.co/z52Fb8GMFW

Aug 25, 2022 · 10 likes · 2 shares · 2,829 followers View post →
ZKForTre
@ZKForTre · X

This is called cherry picking. Meta analysis shows risk is ~12%, while protection/reduction in ascvd events in maintained. Moreover, statins doses below max dose were associated with no difference in diabetes risk. https://t.co/W2d8z0EmMk). https://t.co/z52Fb8GeQo

Aug 23, 2022 · 7 likes · 1 share · 2,829 followers View post →
Krzysztof Kukliński, obrońca praw człowieka
@pamiechomeblog · X

@maciejbanach @krzysztofbukiel @KatarzynaPinkos Panie Macieju, czy skoro deklaruje pan "konflikt interesu", to powinien się pan wypowiadać na ten temat? Kiedyś to było nie do pomyślenia. Z ciekawości zapytam, czy któraś z tych firm produkuje #statyny⬇️? https://t.co/7Z4SzIahF6 #cukrzyca⬆️ https://t.co/IVg9qgBJXA

Jan 17, 2023 · 3 likes · 1 share · 3,458 followers View post →
Tom Marshall
@TomPMarshall · X

@KevinDr_ver This is also misleading. Yes there's a lot of nonsense about statin adverse effects, but they are known to slightly increase risk of diabetes. Therefore recommending them for an additional 20-30 years is not a straightforward decision. https://t.co/rftc7t8rQ7

Jun 4, 2022 · 3 likes · 3,256 followers View post →
م. محمود سعد
@Eng_mahmoudSad · X

المجلة الطبيه البريطانيه لا علاقة لارتفاع الكوليسترول الشديد بالجلطات القلبيه في العوائل المصابه بFH https://t.co/KnPyTgjD8y أدويه الكوليسترول (الستاتين) تسبب السكري دراسه حديثه https://t.co/iDKaWXKzgS https://t.co/IWJXaMOfMt إدارة الغذاء والدواء FDA https://t.co/ExWzzCzq9U https://t.co/FI0P6zbOQH

Aug 7, 2023 · 2 likes · 1,009 followers View post →

All mentions

SCIENMAG
@scienmag.bsky.social · Bluesky

Statins Lower HCC Risk in MASLD, T2DM In a landmark umbrella review published in BMC Cancer, researchers have delved deeply into the complex relationship between statin use and the risk of developing hepatocellular carcinoma (HCC) in individuals afflicted with metabolic dysfunction–associated…

May 14, 2025 View post →
Kerry Bonin
@KerryBonin · X

@rossiadam @LBannon5 https://t.co/GxI5kV0PNP

Jun 1, 2024 · 1 like · 284 followers View post →
MAHAT NSAIF
@MHNASIF · X

RT @Eng_mahmoudSad: @NedaaAlkhamis المجلة الطبيه البريطانيه لا علاقة لارتفاع الكوليسترول الشديد بالجلطات القلبيه في العوائل المصابه بFH ht…

Aug 9, 2023 · 3 shares · 49 followers View post →
Ali 963
@AliKhaddour11 · X

RT @Eng_mahmoudSad: @NedaaAlkhamis المجلة الطبيه البريطانيه لا علاقة لارتفاع الكوليسترول الشديد بالجلطات القلبيه في العوائل المصابه بFH ht…

Aug 8, 2023 · 3 shares · 898 followers View post →
ماجد يوسفان
@MajdYwsfan · X

RT @Eng_mahmoudSad: @NedaaAlkhamis المجلة الطبيه البريطانيه لا علاقة لارتفاع الكوليسترول الشديد بالجلطات القلبيه في العوائل المصابه بFH ht…

Aug 8, 2023 · 3 shares · 63 followers View post →
م. محمود سعد
@Eng_mahmoudSad · X

@NedaaAlkhamis المجلة الطبيه البريطانيه لا علاقة لارتفاع الكوليسترول الشديد بالجلطات القلبيه في العوائل المصابه بFH https://t.co/KnPyTgjD8y أدويه الكوليسترول (الستاتين) تسبب السكري دراسه حديثه https://t.co/iDKaWXKzgS https://t.co/IWJXaMOfMt إدارة الغذاء والدواء FDA https://t.co/ExWzzCzq9U

Aug 7, 2023 · 14 likes · 3 shares · 1,009 followers View post →
م. محمود سعد
@Eng_mahmoudSad · X

المجلة الطبيه البريطانيه لا علاقة لارتفاع الكوليسترول الشديد بالجلطات القلبيه في العوائل المصابه بFH https://t.co/KnPyTgjD8y أدويه الكوليسترول (الستاتين) تسبب السكري دراسه حديثه https://t.co/iDKaWXKzgS https://t.co/IWJXaMOfMt إدارة الغذاء والدواء FDA https://t.co/ExWzzCzq9U https://t.co/FI0P6zbOQH

Aug 7, 2023 · 2 likes · 1,009 followers View post →
Krzysztof Kukliński, obrońca praw człowieka
@pamiechomeblog · X

RT @pamiechomeblog: @maciejbanach @krzysztofbukiel @KatarzynaPinkos Panie Macieju, czy skoro deklaruje pan "konflikt interesu", to powinien…

Feb 26, 2023 · 1 share · 3,458 followers View post →
Krzysztof Kukliński, obrońca praw człowieka
@pamiechomeblog · X

@maciejbanach @krzysztofbukiel @KatarzynaPinkos Panie Macieju, czy skoro deklaruje pan "konflikt interesu", to powinien się pan wypowiadać na ten temat? Kiedyś to było nie do pomyślenia. Z ciekawości zapytam, czy któraś z tych firm produkuje #statyny⬇️? https://t.co/7Z4SzIahF6 #cukrzyca⬆️ https://t.co/IVg9qgBJXA

Jan 17, 2023 · 3 likes · 1 share · 3,458 followers View post →
Alberto Andrade
@Springandashura · X

RT @ZKForTre: Your predilection for cherry picking individual studies where robust meta analyses are readily available is beyond perplexing…

Aug 27, 2022 · 2 shares · 233 followers View post →
Gnoam
@GnoamChachki · X

RT @ZKForTre: Your predilection for cherry picking individual studies where robust meta analyses are readily available is beyond perplexing…

Aug 26, 2022 · 2 shares · 17 followers View post →
ZKForTre
@ZKForTre · X

Your predilection for cherry picking individual studies where robust meta analyses are readily available is beyond perplexing. It’s more like 12% for high-intensity statin regimens. Decreases down to 0 excess risk with moderate intensity ones. https://t.co/W2d8z0EUBS https://t.co/z52Fb8GMFW

Aug 25, 2022 · 10 likes · 2 shares · 2,829 followers View post →
Bhopender Thakur
@TheBhupiThakur · X

RT @ZKForTre: This is called cherry picking. Meta analysis shows risk is ~12%, while protection/reduction in ascvd events in maintained.…

Aug 24, 2022 · 1 share · 1,364 followers View post →
ZKForTre
@ZKForTre · X

This is called cherry picking. Meta analysis shows risk is ~12%, while protection/reduction in ascvd events in maintained. Moreover, statins doses below max dose were associated with no difference in diabetes risk. https://t.co/W2d8z0EmMk). https://t.co/z52Fb8GeQo

Aug 23, 2022 · 7 likes · 1 share · 2,829 followers View post →
Tom Marshall
@TomPMarshall · X

@KevinDr_ver This is also misleading. Yes there's a lot of nonsense about statin adverse effects, but they are known to slightly increase risk of diabetes. Therefore recommending them for an additional 20-30 years is not a straightforward decision. https://t.co/rftc7t8rQ7

Jun 4, 2022 · 3 likes · 3,256 followers View post →
Nick
@upRootNutrition · X

@smurthys Rosuvastatin is where the vast majority of the excess risk is coming from. Other statins, not so much, if at all. https://t.co/FazCVGj2Rw

Jan 22, 2022 · 1 like · 9,522 followers View post →
Biff0178
@John_Bi0 · X

@kevinnbass Links between statins and diabetes dude. https://t.co/KlEKZsSzH8

Jun 3, 2021 · 259 followers View post →
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