August 2016 PMID 27400265

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents.

Dongryeol Ryu, Laurent Mouchiroud, Pénélope A Andreux, Elena Katsyuba, Norman Moullan, Amandine A Nicolet-Dit-Félix, Evan G Williams, Pooja Jha, Giuseppe Lo Sasso, Damien Huzard, Patrick Aebischer, Carmen Sandi, Chris Rinsch, Johan Auwerx

Mentions

274
Peak: 2 in Jan 2020
across 6 sources since Jan 2020

Extended reach

97,952
potential audience

Total likes

1,536

Video views

47,172

Mentions per month

Jan 2020 – Nov 2024

Where it's discussed

  • News215 articles
  • Facebook28 posts
  • X / Twitter12 posts
  • Blogs11 articles
  • YouTube5 videos
  • Reddit3 posts

AI synopsis

What people are saying

The social discussions reflect a general agreement on the promising nature of Urolithin A, with comments highlighting its derivation from foods such as pomegranates and its effects on extending lifespan and muscle health. The tone is moderately enthusiastic, with mentions of its potential use in anti-aging strategies and references to scientific processes like mitophagy, indicating a balanced interest and engagement level.

AgreementModerate agreement

Most discussions recognize the promising results of Urolithin A, supporting its potential benefits for health and aging.

InterestModerate interest

Posts show moderate curiosity, mentioning the compound's origins from foods like pomegranates and its effects on lifespan and muscle function.

EngagementModerate engagement

Several posts reference the biological mechanisms and potential applications, indicating a decent level of in-depth discussion.

ImpactModerate impact

The overall tone suggests that users consider this research potentially influential, especially given its implications for aging and longevity.

Abstract in brief

  • Urolithin A (UA), a natural compound derived from foods like pomegranates, can induce mitophagy, which is the process of clearing damaged mitochondria, thereby supporting cellular health.
  • In studies with C. elegans (a type of worm) and rodents, UA was shown to prevent mitochondrial dysfunction, extend lifespan, and improve muscle function and activity levels during aging.
  • These findings suggest that UA has potential health benefits, especially for enhancing mitochondrial and muscle health, and could be used in strategies to combat age-related decline.]

Top posts

Most liked on X and Bluesky
Joe B
@JBianco215 · X

Urolithin A is produced by microbiome metabolism of ellagitannins, found in pomegranates, raspberries, blackberries, strawberries, & walnuts. Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents https://t.co/KPm2XoDJkF

Jun 6, 2023 · 6 likes · 4,595 followers View post →
Agingdoc
@agingdoc1 · X

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents (2016) https://t.co/aSxVh40c0B

Sep 27, 2022 · 5 likes · 1 share · 41,329 followers View post →
Paul Grant
@321PaulGrant · X

@JohnConstas Urolithin A seem to have promise https://t.co/si9O01SLA1

Jul 20, 2021 · 2 likes · 56 followers View post →
Dharamvir Tanwar
@dharamvirtanwa4 · X

RT @xraytext: Pomegranate's anti-ageing proved https://t.co/3FV5U9vSUe It reacts w/gut bacteria to create anti-ageing compounds +https://…

Oct 14, 2020 · 4 shares · 2,255 followers View post →
Urolithin A
@UrolithinA · X

RT @xraytext: Pomegranate's anti-ageing proved https://t.co/3FV5U9vSUe It reacts w/gut bacteria to create anti-ageing compounds +https://…

Jul 27, 2020 · 4 shares · 881 followers View post →
Andri García
@AndriGarciaOfic · X

RT @xraytext: Pomegranate's anti-ageing proved https://t.co/3FV5U9vSUe It reacts w/gut bacteria to create anti-ageing compounds +https://…

Jul 27, 2020 · 4 shares · 640 followers View post →

All mentions

Joe B
@JBianco215 · X

Urolithin A is produced by microbiome metabolism of ellagitannins, found in pomegranates, raspberries, blackberries, strawberries, & walnuts. Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents https://t.co/KPm2XoDJkF

Jun 6, 2023 · 6 likes · 4,595 followers View post →
Mind Your Science!
@MindYourSci · X

RT @agingdoc1: Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents (2016) https://t…

Sep 27, 2022 · 1 share · 134 followers View post →
Agingdoc
@agingdoc1 · X

Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents (2016) https://t.co/aSxVh40c0B

Sep 27, 2022 · 5 likes · 1 share · 41,329 followers View post →
mmeerm__
@meer__________ · X

Urolithin A induces mitophagy and prolongs lifespan in C. Elegans and increases muscle function in rodents.

Jan 27, 2022 · 4 followers View post →
yaw41380748
@yaw41380748 · X

RT @HotPaperTweet: 【医学】【栄養学】ザクロ果実に腸内細菌がはたらいてできるウロリチンAという物質の抗老化作用が明らかに。センチュウと齧歯類で寿命延長を確認、損傷したミトコンドリアを更新するミトファジーの誘導が鍵だという。 https://t.co/pFT8k…

Jan 6, 2022 · 29 shares · 26 followers View post →
Paul Grant
@321PaulGrant · X

@JohnConstas Urolithin A seem to have promise https://t.co/si9O01SLA1

Jul 20, 2021 · 2 likes · 56 followers View post →
水素ラボ
@suisolabo · X

RT @HotPaperTweet: 【医学】【栄養学】ザクロ果実に腸内細菌がはたらいてできるウロリチンAという物質の抗老化作用が明らかに。センチュウと齧歯類で寿命延長を確認、損傷したミトコンドリアを更新するミトファジーの誘導が鍵だという。 https://t.co/pFT8k…

Jun 30, 2021 · 29 shares · 83 followers View post →
Dharamvir Tanwar
@dharamvirtanwa4 · X

RT @xraytext: Pomegranate's anti-ageing proved https://t.co/3FV5U9vSUe It reacts w/gut bacteria to create anti-ageing compounds +https://…

Oct 14, 2020 · 4 shares · 2,255 followers View post →
Andri García
@AndriGarciaOfic · X

RT @xraytext: Pomegranate's anti-ageing proved https://t.co/3FV5U9vSUe It reacts w/gut bacteria to create anti-ageing compounds +https://…

Jul 27, 2020 · 4 shares · 640 followers View post →
Urolithin A
@UrolithinA · X

RT @xraytext: Pomegranate's anti-ageing proved https://t.co/3FV5U9vSUe It reacts w/gut bacteria to create anti-ageing compounds +https://…

Jul 27, 2020 · 4 shares · 881 followers View post →
Sylvie Vullioud
@SylvieVullioud · X

@fabricedelaye @EPFL @heidi_news @Amazentis1 @wef @EPFLOpenScience @EPFLlibrary Et non, essayez: si vous copiez le titre Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents dans Google, aucun lien sur les 2 premières pages ne donne accès au texte intégral!

Jan 24, 2020 · 317 followers View post →
Sylvie Vullioud
@SylvieVullioud · X

@fabricedelaye @EPFL @heidi_news @Amazentis1 @wef @EPFLOpenScience @EPFLlibrary Pourquoi le service de communication donne un lien ouvert aux journalistes de la version finale de l'article 'Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents' https://t.co/ky85EMTAan

Jan 24, 2020 · 317 followers View post →