Publications by authors named "Penelope A Andreux"

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Urolithin A improves mitochondrial health, reduces cartilage degeneration, and alleviates pain in osteoarthritis.
Davide D'Amico, Merissa Olmer, Andréane M Fouassier, Pamela Valdés, Pénélope A Andreux, Chris Rinsch, Martin Lotz

August 2022

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Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults.
Anurag Singh, Davide D'Amico, Pénélope A Andreux, Andréane M Fouassier, William Blanco-Bose, Mal Evans, Patrick Aebischer, Johan Auwerx, Chris Rinsch

May 2022

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Impact of the Natural Compound Urolithin A on Health, Disease, and Aging.
Davide D'Amico, Pénélope A Andreux, Pamela Valdés, Anurag Singh, Chris Rinsch, Johan Auwerx

Trends Mol Med· July 2021

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The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans.
Pénélope A Andreux, William Blanco-Bose, Dongryeol Ryu, Frédéric Burdet, Mark Ibberson, Patrick Aebischer, Johan Auwerx, Anurag Singh, Chris Rinsch

Nat Metab· June 2019

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Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents.
Dongryeol Ryu, Laurent Mouchiroud, Pénélope A Andreux, Elena Katsyuba, Norman Moullan, Amandine A Nicolet-Dit-Félix, Evan G Williams, Pooja Jha, Giuseppe Lo Sasso, Damien Huzard

August 2016

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The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
Carles Cantó, Riekelt H Houtkooper, Eija Pirinen, Dou Y Youn, Maaike H Oosterveer, Yana Cen, Pablo J Fernandez-Marcos, Hiroyasu Yamamoto, Pénélope A Andreux, Philippe Cettour-Rose

June 2012

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Urolithin A provides cardioprotection and mitochondrial quality enhancement preclinically and improves human cardiovascular health biomarkers.
Sophia Liu, Julie Faitg, Charlotte Tissot, Dimitris Konstantopoulos, Ross Laws, Pénélope A Andreux

iScience· February 2025

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Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy.
Dominic Denk, Valentina Petrocelli, Claire Conche, Moritz Drachsler, Paul K Ziegler, Pénélope A Andreux

Immunity· November 2022

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Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population.
Anurag Singh, Davide D'Amico, Pénélope A Andreux, Gillian Dunngalvin, Timo Kern

Eur J Clin Nutr· February 2022

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Urolithin A improves muscle function by inducing mitophagy in muscular dystrophy.
Peiling Luan, Davide D'Amico, Pénélope A Andreux, Pirkka-Pekka Laurila, Martin Wohlwend

Sci Transl Med· April 2021

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Publisher Correction: Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly.
Pénélope A Andreux, Marcus P J van Diemen, Maxime R Heezen, Johan Auwerx, Chris Rinsch

Sci Rep· November 2019

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Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly.
Pénélope A Andreux, Marcus P J van Diemen, Maxime R Heezen, Johan Auwerx, Chris Rinsch

Sci Rep· June 2018

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An evolutionarily conserved role for the aryl hydrocarbon receptor in the regulation of movement.
Evan G Williams, Laurent Mouchiroud, Michael Frochaux, Ashutosh Pandey, Pénélope A Andreux

PLoS Genet· September 2014

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A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans.
Pénélope A Andreux, Laurent Mouchiroud, Xu Wang, Virginija Jovaisaite, Adrienne Mottis

Sci Rep· June 2014

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The metabolic footprint of aging in mice.
Riekelt H Houtkooper, Carmen Argmann, Sander M Houten, Carles Cantó, Ellen H Jeninga, Pénélope A Andreux

Sci Rep· September 2013

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Pharmacological approaches to restore mitochondrial function.
Pénélope A Andreux, Riekelt H Houtkooper, Johan Auwerx

Nat Rev Drug Discov· June 2013

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Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits.
Autumn M McKnite, Maria Elisa Perez-Munoz, Lu Lu, Evan G Williams, Simon Brewer, Pénélope A Andreux

PLoS One· December 2012

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Systems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traits.
Pénélope A Andreux, Evan G Williams, Hana Koutnikova, Riekelt H Houtkooper, Marie-France Champy

Cell· September 2012

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