PubHawk
Annu Rev Cell Dev Biol October 2016 PMID 27501451

The Heidelberg Screen for Pattern Mutants of Drosophila: A Personal Account.

Eric Wieschaus, Christiane Nüsslein-Volhard

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Mentions

14
Peak: 3 in Dec 2020
across 4 sources since Feb 2019

Extended reach

162,656
potential audience

Total likes

79

Video views

1,575

Mentions per month

Feb 2019 – Aug 2025

Where it's discussed

  • X / Twitter8 posts
  • Blogs3 articles
  • Bluesky2 posts
  • YouTube1 videos

AI synopsis

What people are saying

Several discussions praise the detailed genetic screens and the personal accounts of Nusslein-Volhard and Wieschaus, emphasizing their foundational role in developmental genetics. The use of words like

AgreementModerate agreement

Most discussions support the significance of the Heidelberg Screen and its authors, highlighting the importance of their personal accounts and contributions.

InterestHigh interest

Posts indicate high interest, especially when referencing detailed gene tables, implications for human disease, and genetic methodologies.

EngagementModerate engagement

Comments include references to experiments, genetic screens, and the importance of the work, showing moderate depth of involvement.

ImpactModerate impact

The recognition of the research’s influence on developmental biology and gene discovery suggests a noteworthy impact.

Abstract in brief

  • The Heidelberg Screen for Pattern Mutants of Drosophila was a groundbreaking research effort conducted in 1979-1980 that identified 600 mutants affecting larval cuticle patterns, linked to 120 different genes, which helped uncover key developmental processes.
  • Many of these genes are now known at the molecular level and are conserved across species, including humans, making them valuable for studying human diseases and developmental biology.
  • The mutants, originally discovered through curiosity-driven mutagenesis, have become important models for understanding transcriptional control, cell signaling, and differentiation during development.]
Read the full abstract

Top posts

Most liked on X and Bluesky
さかん　ゆー
@SaKanYoo1 · X

Eric Wieschaus, Chrstiane Nusslein-Volhard本人たちによる個人的な述懐 https://t.co/JXfJCEyzfe

Aug 29, 2025 · 4 likes · 1,383 followers View post →
Stephanie E. Mohr
@smohrfly · X

Nusslein-Volhard and Wieschaus share a personal account of the genetic screens that led to identification of hh and >100 other genes involved in similar processes in “The Heidelberg Screen for Pattern Mutants of Drosophila: A Personal Account” https://t.co/KvrCFeZPNU

Oct 30, 2020 · 3 likes · 947 followers View post →
PZ Myers
@pzmyers · X

This week's Evo Devo Diary is about developmental genetics and the famous Heidelberg Screen! https://t.co/wuRu73rkBW https://t.co/zV2dHnM9AD

Dec 23, 2020 · 1 like · 140,151 followers View post →
jesse veenvliet @jesseveenvliet.bsky.social
@jvveenvliet · X

@peiferlabunc Thanks for the great Perspective! I really loved to read Eric’s personal account: https://t.co/avY2JziCVO

Oct 24, 2024 · 1 like · 1 share · 2,636 followers View post →
The Grand Teuton
@flulrich · X

@kchandra58 @_atanas_ I would add "Christiane Nuesslein-Volhard and Eric Wieschaus discover early patterning genes" to the collection https://t.co/1ehrHJAhBz

Oct 10, 2019 · 1 like · 1,761 followers View post →
Haley Lab
@labohaley.bsky.social · Bluesky

Although it's less direct, you could arguably go way back into model organism genetic screens for examples as well (see Table 1 from this review, which recounts the Heidelberg Drosophila screen from Nüsslein-Volhard and Wieschaus): pubmed.ncbi.nlm.nih.gov/27501451/

Feb 15, 2025 · 1 like View post →

All mentions

さかん　ゆー
@SaKanYoo1 · X

Eric Wieschaus, Chrstiane Nusslein-Volhard本人たちによる個人的な述懐 https://t.co/JXfJCEyzfe

Aug 29, 2025 · 4 likes · 1,383 followers View post →
Haley Lab
@labohaley.bsky.social · Bluesky

Although it's less direct, you could arguably go way back into model organism genetic screens for examples as well (see Table 1 from this review, which recounts the Heidelberg Drosophila screen from Nüsslein-Volhard and Wieschaus): pubmed.ncbi.nlm.nih.gov/27501451/

Feb 15, 2025 · 1 like View post →
Mark Peifer
@peiferlabunc · X

RT @jvveenvliet: @peiferlabunc Thanks for the great Perspective! I really loved to read Eric’s personal account: https://t.co/avY2JziCVO

Oct 24, 2024 · 1 share · 11,859 followers View post →
jesse veenvliet @jesseveenvliet.bsky.social
@jvveenvliet · X

@peiferlabunc Thanks for the great Perspective! I really loved to read Eric’s personal account: https://t.co/avY2JziCVO

Oct 24, 2024 · 1 like · 1 share · 2,636 followers View post →
Annika Reads
@papersofnote · X

For a less scientific and more fun read, also check out this personal account of the Heidelberg mutant screen: https://t.co/3BfaVAUFmv

Oct 26, 2022 · 1,066 followers View post →
PZ Myers
@pzmyers · X

This week's Evo Devo Diary is about developmental genetics and the famous Heidelberg Screen! https://t.co/wuRu73rkBW https://t.co/zV2dHnM9AD

Dec 23, 2020 · 1 like · 140,151 followers View post →
PZ Myers
@pzmyers.bsky.social · Bluesky

This week's Evo Devo Diary is about developmental genetics and the famous Heidelberg Screen! https://freethoughtblogs.com/pharyngula/2020/12/23/who-doesnt-love-the-heidelberg-screen/ https://www.youtube.com/watch?v=RKem9pc9McQ

Dec 23, 2020 View post →
Stephanie E. Mohr
@smohrfly · X

Nusslein-Volhard and Wieschaus share a personal account of the genetic screens that led to identification of hh and >100 other genes involved in similar processes in “The Heidelberg Screen for Pattern Mutants of Drosophila: A Personal Account” https://t.co/KvrCFeZPNU

Oct 30, 2020 · 3 likes · 947 followers View post →
The Grand Teuton
@flulrich · X

@kchandra58 @_atanas_ I would add "Christiane Nuesslein-Volhard and Eric Wieschaus discover early patterning genes" to the collection https://t.co/1ehrHJAhBz

Oct 10, 2019 · 1 like · 1,761 followers View post →
Ciera Martinez, PhD
@CieraReports · X

Via Colleen, this review systematically discusses dev. Drosophila genes. Experiments are laid out extremely well w/ detailed genetic screens! Extremely organized representation of phenotypes. Bonus: Thorough table of genes w/ human orthologs. Paper: https://t.co/TA04rtXvrZ

Feb 28, 2019 · 1,274 followers View post →