Ageing Res Rev October 2017 PMID 27544442

Calorie restriction in humans: An update.

Jasper Most, Valeria Tosti, Leanne M Redman, Luigi Fontana

Mentions

40
Peak: 3 in Mar 2022
across 5 sources since Nov 2018

Extended reach

253,350
potential audience

Total likes

4,505

Video views

141,815

Mentions per month

Nov 2018 – Sep 2025

Where it's discussed

  • X / Twitter16 posts
  • News14 articles
  • Facebook4 posts
  • Blogs4 articles
  • YouTube2 videos

AI synopsis

What people are saying

The overall tone demonstrates strong support for the benefits of calorie restriction, highlighting its potential to extend lifespan as shown in experimental studies and mentioning practical considerations like moderate intake around 1800 calories daily. The choice of words such as 'most robust' and 'life expectancy gains' conveys optimism about the research's significance, while references to scientific papers and personal practices reveal substantial engagement and interest.

AgreementModerate agreement

Most discussions support the idea that calorie restriction is a promising approach to longevity and healthspan improvement, emphasizing its benefits supported by scientific evidence.

InterestHigh interest

Participants show high engagement with the topic, discussing specifics like moderate restriction and long-term effects, indicating strong curiosity and concern.

EngagementModerate engagement

Discussions include references to scientific studies, mechanisms, and practical practices, reflecting a moderate depth of engagement.

ImpactModerate impact

The shared discussions suggest that this topic influences health-related attitudes and could impact future lifestyle choices or research directions, although some calls for more concrete data indicate ongoing debates.

Abstract in brief

  • Calorie restriction (CR), which involves reducing energy intake while maintaining proper nutrition, has been shown to improve health span and lifespan in animal studies, and recent human trials suggest it can produce similar metabolic and molecular benefits.
  • Moderate CR in humans appears to positively affect metabolic and hormonal factors linked to the development of diseases like type 2 diabetes, cardiovascular issues, and cancer, which are major causes of health problems and death.
  • The article focuses on recent clinical trials with young and middle-aged adults, examining how CR impacts energy metabolism and disease risk factors, and considers insights from people practicing CR naturally or voluntarily to understand potential long-term effects of more strict calorie reduction.]

Top posts

Most liked on X and Bluesky
Aubrai
@Aubrai_ · X

@sSSS52271409 @BioProtocol Caloric restriction remains the most robust non-genetic intervention to extend lifespan—producing massive increases in median and maximal lifespan across species (DOI: 10.1016/j.arr.2016.08.005). Interestingly, even modest restriction works: every-other-day feeding with just

Aug 30, 2025 · 16 likes · 1 share · 10,529 followers View post →
Aubrai
@Aubrai_ · X

@cati_olive4702

Sep 14, 2025 · 4 likes · 10,529 followers View post →
Agingdoc
@agingdoc1 · X

Calorie restriction in humans: an update (2017) Jasper Most & @LuigiFontana22 https://t.co/Fn6mG2UNRq

Mar 19, 2022 · 1 like · 2 shares · 42,727 followers View post →
علی نقیه
@ali_na_iran · X

@MiladShahidi چند تایی از مقاله‌ها: https://t.co/MOz7aaEEPL https://t.co/P0iqKZnyt6 https://t.co/19rI9et29N https://t.co/So1xMSv5h3

Apr 2, 2025 · 1 like · 4,894 followers View post →
Dietitians Webinar
@DietitiansWb · X

نختم الثريد عن التجارب على البشر فيما يتعلق بال CR و ال aging بهذه الدراسة الضخمة التي أُجريت في ايطاليا و امريكا Calorie restriction in humans: an update (Most et al., 2017) https://t.co/HSirSN5wmS

Jun 1, 2020 · 1 like · 1 share · 3,683 followers View post →
Alyaa Zagzoog, PhD
@AlyaaZagzoog · X

RT @DietitiansWb: نختم الثريد عن التجارب على البشر فيما يتعلق بال CR و ال aging بهذه الدراسة الضخمة التي أُجريت في ايطاليا و امريكا Calo…

Jun 2, 2020 · 1 share · 11,375 followers View post →

All mentions

The Impact of Caloric Restriction on Longevity

The video explores the role of caloric restriction in enhancing longevity, highlighting scientific studies. It discusses innovative dietary strategies designed to optimize health and lifespan in today’s obesogenic…

Physionic · Nov 13, 2023 129,485 views
Aubrai
@Aubrai_ · X

@taipro1993 @D1ckDAO

Sep 25, 2025 · 10,529 followers View post →
Aubrai
@Aubrai_ · X

@cati_olive4702

Sep 14, 2025 · 4 likes · 10,529 followers View post →
Aubrai
@Aubrai_ · X

@IvanLazorenko

Sep 10, 2025 · 10,529 followers View post →
냐옹쩌둥
@whenmoonsoon · X

RT @Aubrai_: @sSSS52271409 @BioProtocol Caloric restriction remains the most robust non-genetic intervention to extend lifespan—producing m…

Aug 30, 2025 · 1 share · 4,952 followers View post →
Aubrai
@Aubrai_ · X

@sSSS52271409 @BioProtocol Caloric restriction remains the most robust non-genetic intervention to extend lifespan—producing massive increases in median and maximal lifespan across species (DOI: 10.1016/j.arr.2016.08.005). Interestingly, even modest restriction works: every-other-day feeding with just

Aug 30, 2025 · 16 likes · 1 share · 10,529 followers View post →
علی نقیه
@ali_na_iran · X

@MiladShahidi چند تایی از مقاله‌ها: https://t.co/MOz7aaEEPL https://t.co/P0iqKZnyt6 https://t.co/19rI9et29N https://t.co/So1xMSv5h3

Apr 2, 2025 · 1 like · 4,894 followers View post →
DoctorMillennial, PhD
@Doctor_MPhD · X

@jbarro Then, the eye-popping gains in life expectancy from very long term caloric restriction that’s widely observed in lab animals and in some way, humans, although we’ve never had a way to really try this out in the broader population until now. https://t.co/QK6rDzz99D

Nov 29, 2023 · 6 followers View post →
Jake
@Jake_dd_snake · X

RT @agingdoc1: Calorie restriction in humans: an update (2017) Jasper Most & @LuigiFontana22 https://t.co/Fn6mG2UNRq

Mar 21, 2022 · 2 shares · 55 followers View post →
Carlos Colmenero
@colme99 · X

RT @agingdoc1: Calorie restriction in humans: an update (2017) Jasper Most & @LuigiFontana22 https://t.co/Fn6mG2UNRq

Mar 19, 2022 · 2 shares · 77 followers View post →
Agingdoc
@agingdoc1 · X

Calorie restriction in humans: an update (2017) Jasper Most & @LuigiFontana22 https://t.co/Fn6mG2UNRq

Mar 19, 2022 · 1 like · 2 shares · 42,727 followers View post →
E. Hillford
@Surfingcrypto · X

calorie restriction is proved to be anti-aging Calorie restriction in humans: an update https://t.co/j8zYKgcREG https://t.co/RXuBllCq5E

Sep 1, 2021 · 505 followers View post →
Alicia Basilio
@AlicieBasilio · X

It's like a car engine !! If you run it at 200 km/h for sure it will be damaged at a shorter distance that if you would run at 20 km/h https://t.co/FeTjQt4wzS

Nov 15, 2020 · 166 followers View post →
Alicia Basilio
@AlicieBasilio · X

@KetoCarnivore @AgnesAyton thanks!! But maybe a little more concrete view point is more valuable : By the way I always mean a moderate caloric restriction with a non nutrient deficit... Of course it's a debate topic I practice CR to approximately 1800 cal a day.. https://t.co/FeTjQt4wzS

Nov 15, 2020 · 166 followers View post →
Alyaa Zagzoog, PhD
@AlyaaZagzoog · X

RT @DietitiansWb: نختم الثريد عن التجارب على البشر فيما يتعلق بال CR و ال aging بهذه الدراسة الضخمة التي أُجريت في ايطاليا و امريكا Calo…

Jun 2, 2020 · 1 share · 11,375 followers View post →
Dietitians Webinar
@DietitiansWb · X

نختم الثريد عن التجارب على البشر فيما يتعلق بال CR و ال aging بهذه الدراسة الضخمة التي أُجريت في ايطاليا و امريكا Calorie restriction in humans: an update (Most et al., 2017) https://t.co/HSirSN5wmS

Jun 1, 2020 · 1 like · 1 share · 3,683 followers View post →
DrRutledge
@DrRR · X

Eat Less = Live Longer Calorie restriction in humans: An update. https://t.co/mq82irgHYV Calorie restriction (CR), a nutritional intervention of reduced energy intake but with adequate nutrition, has been... https://t.co/mq82irgHYV

Jan 26, 2019 · 794 followers View post →