August 2016 PMID 27557301

A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor.

W Jeffrey Elias, Nir Lipsman, William G Ondo, Pejman Ghanouni, Young G Kim, Wonhee Lee, Michael Schwartz, Kullervo Hynynen, Andres M Lozano, Binit B Shah, Diane Huss, Robert F Dallapiazza, Ryder Gwinn, Jennifer Witt, Susie Ro

Mentions

94
Peak: 4 in Nov 2021
across 6 sources since Aug 2019

Extended reach

28,008
potential audience

Total likes

118

Video views

1,794

Mentions per month

Aug 2019 – Apr 2025

Where it's discussed

  • News58 articles
  • X / Twitter16 posts
  • Facebook12 posts
  • Blogs4 articles
  • YouTube2 videos
  • Reddit2 posts

AI synopsis

What people are saying

The collective discussions highlight the promising results of the ultrasound thalamotomy, with examples mentioning its effectiveness in reducing tremors and the treatment's potential to change clinical practices. The tone varies from technical descriptions to perspectives on innovation, emphasizing both scientific curiosity and potential societal impact.

AgreementModerate agreement

Most discussions acknowledge the significance of the study, indicating general support for the findings on focused ultrasound as an effective treatment.

InterestHigh interest

Posts demonstrate high curiosity about the procedure, trial design, and clinical implications, reflecting strong interest in the research.

EngagementModerate engagement

Some posts delve into detailed aspects like trial methods, neural targets, and the novelty of the technology, showing moderate but meaningful engagement.

ImpactModerate impact

Comments suggest that these studies could influence clinical practice and insurance policies, indicating a recognition of potential high-impact outcomes.

Abstract in brief

  • The study evaluated the effectiveness of focused ultrasound thalamotomy, guided by MRI, for treating moderate to severe essential tremor in patients unresponsive to medication, and found that the treatment significantly reduced tremor severity compared to a sham procedure.
  • Patients who received the actual treatment showed sustained improvement in tremor and quality of life measures that lasted at least 12 months, with the most notable benefits observed at 3 months.
  • However, there were notable side effects such as gait disturbance and numbness or paresthesias, which persisted in some patients up to 12 months after treatment.]

Top posts

Most liked on X and Bluesky
Dr. Nina Niu Sanford
@NiuSanford · X

Need more RCTs of RT in benign conditions like tremor, osteoarthritis Otherwise won't gain traction w anecdotes b/c of negative RT connotations Here is a sham controlled RCT of ultrasound for tremor. Need similar for RT (better yet compare ultrasound) https://t.co/6IhzCeeO7p https://t.co/hczkTCjAVy

Jun 15, 2023 · 30 likes · 9,670 followers View post →
Taylor Lawrence
@TaylorLUNHM · X

https://t.co/X5zuRGq8EK is the article I read relating to my topic of essential tremor. The main takeaway from this would be that a non invasive treatment focused ultrasound thalamotomy successfully can reduce the shaking in an ET patient's hands. #prescottgenomics

Feb 27, 2022 · 7 likes · 7 followers View post →
さすらい脳外科医
@sasuraiNS · X

本態性振戦に対するFUS(MRIガイド下集束超音波治療)のdouble blind trial 視床腹側中核核(Vim核)の熱凝固は振戦を有意に減らすが、歩行障害などの合併症例報告もあり  本邦では2020年より保険適応 #脳外科 https://t.co/UnSVe4v2nu

Nov 15, 2021 · 3 likes · 4 shares · 870 followers View post →
Precious
@precious_Ebii · X

Review of A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor Treatment: Determining the history, trial design, evidence, treatment and challenges https://t.co/aqGjN9aCtx

Nov 29, 2022 · 3 likes · 2 shares · 400 followers View post →
Ayaka Kato
@kayautoka · X

ここ数年で臨床的にもかなり普及してきていてNEJMにも複数論文が出てるみたい。例えば↓ https://t.co/yMIikBTC4h

Feb 19, 2020 · 2 likes · 6,089 followers View post →
Samurai-NeuroSurgeon
@sasurai_NS · X

A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor It targets the nucleus ventral is intermedius of the thalamus This therapy is applicable to insurance in Japan from 2020 #neurosurgery https://t.co/GWQVhkGH9s

Nov 15, 2021 · 1 like · 1 share · 19 followers View post →

All mentions

Dr. Nina Niu Sanford
@NiuSanford · X

Need more RCTs of RT in benign conditions like tremor, osteoarthritis Otherwise won't gain traction w anecdotes b/c of negative RT connotations Here is a sham controlled RCT of ultrasound for tremor. Need similar for RT (better yet compare ultrasound) https://t.co/6IhzCeeO7p https://t.co/hczkTCjAVy

Jun 15, 2023 · 30 likes · 9,670 followers View post →
De Machine Learning Hub
@MLhub_ · X

RT @precious_Ebii: Review of A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor Treatment: Determining the history,…

Nov 29, 2022 · 2 shares · 13 followers View post →
Precious
@precious_Ebii · X

RT @precious_Ebii: Review of A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor Treatment: Determining the history,…

Nov 29, 2022 · 2 shares · 400 followers View post →
Precious
@precious_Ebii · X

Review of A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor Treatment: Determining the history, trial design, evidence, treatment and challenges https://t.co/aqGjN9aCtx

Nov 29, 2022 · 3 likes · 2 shares · 400 followers View post →
QxMD | Your Personalized Medical Journal
@QxMD · X

A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor: https://t.co/h4mJMFjhze Dr @carolinejust addresses the questions behind these remarkable results and reveals the impact on clinical practice. All the essentials ... essentially! #Tremor #NeuroTwitter https://t.co/wYHXUxH6Pb

Jul 20, 2022 · 5,548 followers View post →
キリコ
@KirikoGT97 · X

RT @sasuraiNS: 本態性振戦に対するFUS(MRIガイド下集束超音波治療)のdouble blind trial 視床腹側中核核(Vim核)の熱凝固は振戦を有意に減らすが、歩行障害などの合併症例報告もあり  本邦では2020年より保険適応 #脳外科 htt…

Jun 26, 2022 · 4 shares · 24 followers View post →
Mohamed Khattab, MD
@MKhattabMD · X

@EMiddlebrooksMD @MichaelOkun @KDFooteMD @DrAlfonsoFasano @andreashorn_ https://t.co/Io4nXDzrZ0

May 18, 2022 · 378 followers View post →
八田理絵(HattaRie)│言語聴覚士(ST)│
@RieHatta · X

RT @sasuraiNS: 本態性振戦に対するFUS(MRIガイド下集束超音波治療)のdouble blind trial 視床腹側中核核(Vim核)の熱凝固は振戦を有意に減らすが、歩行障害などの合併症例報告もあり  本邦では2020年より保険適応 #脳外科 htt…

Mar 12, 2022 · 4 shares · 358 followers View post →
Taylor Lawrence
@TaylorLUNHM · X

https://t.co/X5zuRGq8EK is the article I read relating to my topic of essential tremor. The main takeaway from this would be that a non invasive treatment focused ultrasound thalamotomy successfully can reduce the shaking in an ET patient's hands. #prescottgenomics

Feb 27, 2022 · 7 likes · 7 followers View post →
林田とし枝
@Z5Tvn · X

RT @sasuraiNS: 本態性振戦に対するFUS(MRIガイド下集束超音波治療)のdouble blind trial 視床腹側中核核(Vim核)の熱凝固は振戦を有意に減らすが、歩行障害などの合併症例報告もあり  本邦では2020年より保険適応 #脳外科 htt…

Jan 8, 2022 · 4 shares · 1 followers View post →
FUS後で震え止まった@本態性振戦の40代で職人
@stopmytremors · X

RT @sasuraiNS: 本態性振戦に対するFUS(MRIガイド下集束超音波治療)のdouble blind trial 視床腹側中核核(Vim核)の熱凝固は振戦を有意に減らすが、歩行障害などの合併症例報告もあり  本邦では2020年より保険適応 #脳外科 htt…

Nov 17, 2021 · 4 shares · 14 followers View post →
NeurosurgeryBot
@NeurosurgeryBot · X

RT @sasurai_NS: A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor It targets the nucleus ventral is intermedius of…

Nov 15, 2021 · 1 share · 1,915 followers View post →
Samurai-NeuroSurgeon
@sasurai_NS · X

A Randomized Trial of Focused Ultrasound Thalamotomy for Essential Tremor It targets the nucleus ventral is intermedius of the thalamus This therapy is applicable to insurance in Japan from 2020 #neurosurgery https://t.co/GWQVhkGH9s

Nov 15, 2021 · 1 like · 1 share · 19 followers View post →
さすらい脳外科医
@sasuraiNS · X

本態性振戦に対するFUS(MRIガイド下集束超音波治療)のdouble blind trial 視床腹側中核核(Vim核)の熱凝固は振戦を有意に減らすが、歩行障害などの合併症例報告もあり  本邦では2020年より保険適応 #脳外科 https://t.co/UnSVe4v2nu

Nov 15, 2021 · 3 likes · 4 shares · 870 followers View post →
Ayaka Kato
@kayautoka · X

ここ数年で臨床的にもかなり普及してきていてNEJMにも複数論文が出てるみたい。例えば↓ https://t.co/yMIikBTC4h

Feb 19, 2020 · 2 likes · 6,089 followers View post →
iExpiredAccount
@iExpiredAccount · X

1. Focused us/s is relatively new and only 1 functional neurosurgeon conducts it in BWH 2. The rarity of conducting a double blinded RCT in neurosugery! #functionalneurosurgery #neurosurgery https://t.co/4rcOW91omU

Aug 18, 2019 · 453 followers View post →