Defibrillator Implantation in Patients with Nonischemic Systolic Heart Failure.
Lars Køber, Jens J Thune, Jens C Nielsen, Jens Haarbo, Lars Videbæk, Eva Korup, Gunnar Jensen, Per Hildebrandt, Flemming H Steffensen, Niels E Bruun, Hans Eiskjær, Axel Brandes, Anna M Thøgersen, Finn Gustafsson, Kenneth Egstrup
September 2016 N Engl J MedSynopsis of Social media discussions
The analysis reflects a nuanced view of the article, with some posts referencing the DANISH trial's findings that ICDs do not significantly lower overall mortality in non-ischemic cases, while others detail factors like age and new medications that influence outcomes. The tone combines technical language with critical perspective, emphasizing the complexity of applying trial data to clinical decisions.
Agreement
Neither agree nor disagreePosts show mixed opinions; some agree with the study's findings while others point out limitations or contextual nuances.
Interest
Moderate level of interestDiscussions demonstrate moderate interest, with people engaging in technical details and referencing previous studies.
Engagement
Moderate level of engagementPosts delve into detailed analysis of the trial data, subgroup differences, and implications, indicating active engagement.
Impact
Neutral impactThe discussions highlight ongoing debates and the relevance of the study results but do not suggest widespread immediate change in practice.
Social Mentions
YouTube
6 Videos
21 Posts
19 Posts
Blogs
6 Articles
News
17 Articles
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1,734
Total Likes
78
Extended Reach
203,934
Social Features
69
Timeline: Posts about article
Top Social Media Posts
Benedikt Schrage
Furthermore, DANISH has shown that ICDs are not associated with lower mortality in patients with non-ischemic HFrEF, although this trial is not free of skepticism (lots of CRT, statistical power potentially too low). https://t.co/yVTxu9G2QH 6/x
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Prof Chris P Gale
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Casey McQuade, MD, MS Ed.
DANISH study, 2016 @NEJM:
For patients with HFrEF with NICM, ICD compared with usual care resulted in no change in all-cause mortality and a small decrease in sudden cardiac death.
https://t.co/MD9zm9KUHs
view full post
John Mandrola, MD
@f2harrell @venkmurthy @ProfHayward @JeremySussman Dear Professors. Could you comment on DANISH? Overall results -> non-sig, but age seemed to modify ICD benefit — both in terms of ARR (see event rates in subgroup) and in RRR (displayed) https://t.co/GtxDocveuE https://t.co/Bqup1r92rq
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Yogesh Reddy
@djc795 @GreggWStone @wordfinga @ovidiogarciav @RMSSAA @VictorDayan1 @rafasadaba @pomyers @FaisalBakaeen @JoeSabik @Migas2001 Hence DANISH results https://t.co/a11H1MkrnF.
Which are already outdated since new meds ARNIs and SGLT2i decrease sudden death risk in addition. Its impossible for trials to be up to date so extrapolating changing risks of therapy over time is the best we can do until new trials
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Assessing ICD Use in Nonischemic Systolic Heart Failure Patients
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心臓デバイス入門 ウェビナーシリーズ ICD編 以下、研究報告についての文献です
view full postSeptember 6, 2024
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Ronnie DePesa
@ronniedepesa (Twitter)Mar 22 2024 This Week in Cardiology https://t.co/6Gy3WnE1Ba via @YouTube
view full postMarch 22, 2024
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Søren Zöga Diederichsen
@SZDiederichsen (Twitter)@TorBiering @drjohnm @kaulcsmc Of course subgroups etc shouldn't be part of the abstract in NEJM. But I think nuance is good though. Think about in DANISH, negative trial but everybody talks about the interaction with age https://t.co/DXu91ajKtn
view full postAugust 30, 2022
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Linda
@wordfinga (Twitter)RT @yreddyhf: @djc795 @GreggWStone @wordfinga @ovidiogarciav @RMSSAA @VictorDayan1 @rafasadaba @pomyers @FaisalBakaeen @JoeSabik @Migas2001…
view full postJuly 26, 2022
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Yogesh Reddy
@yreddyhf (Twitter)@djc795 @GreggWStone @wordfinga @ovidiogarciav @RMSSAA @VictorDayan1 @rafasadaba @pomyers @FaisalBakaeen @JoeSabik @Migas2001 Hence DANISH results https://t.co/a11H1MkrnF. Which are already outdated since new meds ARNIs and SGLT2i decrease sudden death risk in addition. Its impossible for trials to be up to date so extrapolating changing risks of therapy over time is the best we can do until new trials
view full postJuly 26, 2022
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Linda
@wordfinga (Twitter)RT @BenediktSchrage: Furthermore, DANISH has shown that ICDs are not associated with lower mortality in patients with non-ischemic HFrEF, a…
view full postJune 22, 2022
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Andrew J Sauer MD
@AndrewJSauer (Twitter)RT @BenediktSchrage: Furthermore, DANISH has shown that ICDs are not associated with lower mortality in patients with non-ischemic HFrEF, a…
view full postJune 20, 2022
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Benedikt Schrage
@BenediktSchrage (Twitter)Furthermore, DANISH has shown that ICDs are not associated with lower mortality in patients with non-ischemic HFrEF, although this trial is not free of skepticism (lots of CRT, statistical power potentially too low). https://t.co/yVTxu9G2QH 6/x
view full postJune 19, 2022
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Prof Chris P Gale
@cpgale3 (Twitter)January 18, 2022
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Pablo Richly
@PabloRichly (Twitter)@drdiegocosta @norabar Por lo que veo no tuvo efecto en mortalidad global o cardiovascular, pero si en muerte súbita (similar a la que pasa con la mamografia). https://t.co/xayM75fOpM ¿No debería repetirse con una mejor muestra?
view full postJanuary 18, 2021
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John Mandrola, MD
@drjohnm (Twitter)@ESMDcan123 @kaulcsmc @venkmurthy @brophyj @f2harrell @ADAlthousePhD Yes, https://t.co/WutoHpInZ3. This is why Danish was null https://t.co/GtxDocveuE
view full postDecember 17, 2020
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Bao Tran, MD
@BaoGTran (Twitter)@AdityaMandawat For anyone over 60 I usually do some sort of anatomic testing either CTA or cath. Was SPECT done with CT attenuation? Can look and see estimate of coronary calcium burden. Also, if nonischemic why AICD? https://t.co/6I2i8T9dtd
view full postMay 5, 2020
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Malvinder Parmar
@wittykidney (Twitter)@DavidLBrownMD @VictorDayan1 If this person’s reduced LV function is from underlying CM - i.e., non-ischemic, then prophylactic ICD, may have similar outcome https://t.co/hmx3fhuPAw
view full postNovember 15, 2019
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Cardiology
@PracUpCardio (Twitter)Duration of Heart Failure and Effect of Defibrillator Implantation in Patients With Nonischemic Systolic #HeartFailure - https://t.co/Dk0935M8RX #cardiology
view full postOctober 8, 2019
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Chile717
@Chile7171 (Twitter)RT @FormigaFrancesc: Duration of Heart Failure and Effect of Defibrillator Implantation in Patients With Nonischemic Systolic Heart Failure…
view full postSeptember 11, 2019
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Francesc Formiga
@FormigaFrancesc (Twitter)Duration of Heart Failure and Effect of Defibrillator Implantation in Patients With Nonischemic Systolic Heart Failure | Circulation: Heart Failure https://t.co/c1NeSvpky0
view full postSeptember 11, 2019
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Christine Chapman
@cchapman1957 (Twitter)RT @CaseMcQuade: DANISH study, 2016 @NEJM: For patients with HFrEF with NICM, ICD compared with usual care resulted in no change in all-c…
view full postMay 12, 2019
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Casey McQuade, MD, MS Ed.
@CaseyMcQuadeMD (Twitter)DANISH study, 2016 @NEJM: For patients with HFrEF with NICM, ICD compared with usual care resulted in no change in all-cause mortality and a small decrease in sudden cardiac death. https://t.co/MD9zm9KUHs
view full postMay 12, 2019
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John Mandrola, MD
@drjohnm (Twitter)@f2harrell @venkmurthy @ProfHayward @JeremySussman Dear Professors. Could you comment on DANISH? Overall results -> non-sig, but age seemed to modify ICD benefit — both in terms of ARR (see event rates in subgroup) and in RRR (displayed) https://t.co/GtxDocveuE https://t.co/Bqup1r92rq
view full postMarch 5, 2019
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Abstract Synopsis
- The study investigated the impact of implantable cardioverter-defibrillators (ICDs) on patients with symptomatic systolic heart failure not caused by coronary artery disease, comparing ICD treatment with usual clinical care.
- A total of 1,116 patients were enrolled, and after 67.6 months, it was found that ICDs did not significantly lower overall mortality rates compared to the control group, although they did reduce instances of sudden cardiac death.
- The findings suggest that while ICDs may have benefits for sudden cardiac death prevention, they do not significantly improve long-term survival rates in this specific patient population.
Dr.トモ＠心電図オタク
@ecgotaku (Twitter)