Syst Rev September 2016 PMID 27589952

A systematic review of St. John's wort for major depressive disorder.

Eric A Apaydin, Alicia R Maher, Roberta Shanman, Marika S Booth, Jeremy N V Miles, Melony E Sorbero, Susanne Hempel

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Mentions

Peak: 3 in Jun 2022

across 5 sources since Mar 2019

Extended reach

325,332

potential audience

Total likes

5,493

Video views

217,407

Mentions per month

Mar 2019 – Jan 2025

Where it's discussed

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AI synopsis

What people are saying

The group shows a balanced interest in SJW's therapeutic potential, with posts referencing studies and debate-like comments on its effectiveness and safety. Words like 'maravilla' (wonder) and phrases such as 'less side effects' illustrate positive perceptions, while others call the review a 'systematic study,' reflecting engagement with the research. Overall, discussions acknowledge the review's contribution but also note the need for further research, indicating moderate impact.

AgreementModerate agreement

Most discussions acknowledge the findings of the review supporting SJW's effectiveness with some reservations about variability in results.

InterestModerate interest

Posts show moderate interest, with some emphasizing the potential of SJW as an alternative treatment while others simply share the information.

EngagementModerate engagement

Comments include references to studies, mentions of side effects, and debates over the herb's efficacy, indicating a moderate level of engagement.

ImpactModerate impact

Many contributors recognize the significance of the review in highlighting SJW's role in depression treatment, suggesting a moderate impact on perceptions and discussions.

Abstract in brief

This systematic review analyzed studies on Saint John’s Wort (SJW) to determine its effectiveness and safety for treating Major Depressive Disorder (MDD), comparing it to placebo and antidepressants, and considering how severity affects outcomes.
The review included 35 randomized controlled trials with around 6,993 patients, finding that SJW was more effective than placebo in helping depression and had fewer side effects than antidepressants, especially for mild to moderate depression.
Overall, the evidence suggests SJW could be a good alternative to antidepressants for some people, but the studies showed some variability in results, so more research is needed to confirm these findings.]

Read the full abstract

All mentions

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Efficacy and Safety of St John's Wort for Major Depressive Disorder

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Evaluating St John's Wort Effectiveness for Major Depressive Disorder

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Medwiki Bengali · Sep 2, 2024 56 views

Nathalia Le Hen

@NathaliaLeHen · X

@knowmedge ✅St. John's Wort

Jan 19, 2025 · 1 like · 2,785 followers View post →

Bannside Pharmacy

@BannsidePharmcy · X

@DrMcFillin https://t.co/so7pjQxX0g

Apr 19, 2023 · 511 followers View post →

Satisfactory Dave

@docdave53 · X

@andrea_weymouth https://t.co/ubSFXcdjIs

Feb 9, 2023 · 1,642 followers View post →

Stefan Linnow / Van de FX / Tripp a FX

@TrippaFx · X

Johanniskraut - Psychoaktive Heilpflanze gegen Depressionen? Standort, M... https://t.co/izqgmXU5TC via @YouTube

Oct 6, 2022 · 317 followers View post →

Nutrem

@MxNutrem · X

@Natchlev El hiperico es una maravilla para depresión por ejemplo y con menores side effects que los antidepresivos normales. https://t.co/uiLs029GYM https://t.co/cGOS0r7iCq

Aug 13, 2022 · 1 like · 257 followers View post →

Dida

@Dida_ti · X

RT @FranciscusScho3: Johanniskraut - Heilpflanze gegen Depressionen? https://t.co/lKmrzOG0VZ via @YouTube

Jul 6, 2022 · 2 shares · 54,339 followers View post →

La familia humana está por la paz.

@herooftheair · X

RT @FranciscusScho3: Johanniskraut - Heilpflanze gegen Depressionen? https://t.co/lKmrzOG0VZ via @YouTube

Jul 6, 2022 · 2 shares · 1,933 followers View post →

Franciscus Scholtheis

@FranciscusScho3 · X

Johanniskraut - Heilpflanze gegen Depressionen? https://t.co/lKmrzOG0VZ via @YouTube

Jul 6, 2022 · 3 likes · 2 shares · 1,213 followers View post →

Michael Beckert

@MichaelBeckert2 · X

RT @MichaelBeckert2: Johanniskraut - Magische Blüten gegen Depressionen? https://t.co/NYZslS8uSA via @YouTube

Jun 24, 2022 · 1 share · 530 followers View post →

Michael Beckert

@MichaelBeckert2 · X

Johanniskraut - Magische Blüten gegen Depressionen? https://t.co/NYZslS8uSA via @YouTube

Jun 24, 2022 · 1 like · 1 share · 530 followers View post →

Diane Proulx

@dianedany · X

@YvanDutil @LP_LaPresse Mais si vous préférez NCBI pubmed, une révision de 35 études sur le millepertuis (plus récente, 2016) https://t.co/g5M1ts5lVQ

Apr 28, 2021 · 98 followers View post →

SystematicReviewBot

@EvidenceRobot · X

RT @briandavidearp: A systematic review of St. John’s wort for major depressive disorder https://t.co/8WFx9cO1HZ

Mar 19, 2020 · 1 share · 6,711 followers View post →

Brian D. Earp, Ph.D.

@briandavidearp · X

A systematic review of St. John’s wort for major depressive disorder https://t.co/8WFx9cO1HZ

Mar 19, 2020 · 4 likes · 1 share · 26,093 followers View post →

The Skeptical Clinician ⚕

@TheScepticalDoc · X

@compandalt A systematic review of St. John’s wort for major depressive disorder https://t.co/gTG34Vx3sw

Oct 1, 2019 · 1 like · 280 followers View post →

SystematicReviewBot

@EvidenceRobot · X

RT @muttslikeme: SJW #PiDay & A systematic review of St. John’s wort for major depressive disorder Eric A. Apaydin, Alicia R. Maher, [..…

Mar 14, 2019 · 1 share · 6,711 followers View post →

muttslikeme

@muttslikeme · X

SJW #PiDay & A systematic review of St. John’s wort for major depressive disorder Eric A. Apaydin, Alicia R. Maher, [...], and Susanne Hempel https://t.co/hesxkE0GyT https://t.co/Pp61kH5KdV

Mar 14, 2019 · 1 share · 3,952 followers View post →