Effects of Once-Weekly
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.
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Jun 2019 – Oct 2025Where it's discussed
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AI synopsis
What people are saying
Discussions consistently praise the robust evidence from trials like SUSTAIN-6 and Pioneer 6, exemplified by statements such as 'semaglutide reduces CV events by 20%' and 'shows real positive benefits.' The use of technical terms and references to specific studies demonstrates deep engagement and underscores the high impact of the findings on medical practice.
Most discussions highlight the positive cardiovascular outcomes associated with semaglutide, showing strong support for its benefits.
The discussions demonstrate high interest through mention of detailed study results, side effects, and potential implications for treatment.
Many posters reference specific trials, statistics, and mechanisms, indicating deep engagement with the research.
The overall tone emphasizes semaglutide’s significant potential to influence treatment guidelines and improve patient outcomes.
Abstract in brief
- The study assessed the cardiovascular safety of semaglutide, a diabetes treatment, in type 2 diabetes patients over a 104-week period.
- Among the 3297 participants, semaglutide users had a lower incidence of cardiovascular events compared to the placebo group, indicating potential cardiovascular benefits.
- However, while semaglutide showed lower rates of kidney issues, it was associated with higher rates of retinopathy complications, highlighting a need for careful monitoring.
Top posts
Most liked on X and Bluesky#VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.co/vfSvtmms4a
* CORRECTION 6-20 bpm⬆️is for dual agonists, not semgalutide 1mg semaglutide⬆️heart rate 2.47 bpm above that of the placebo group's https://t.co/TAgV1dYiJp (Table S10) 0.5mg semaglutide⬆️2 BPM, so 2.5mg semaglutide may⬆️> 4-5 bpm "resting heart rate is a predictor of
Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. Context: This is the third RCT to show CV event reduction with sema. https://t.co/1gvqimJ3Hm https://t.co/oTQfAhNe79 https://t.co/dLsjoqY7Ns
Como sempre, os leigos falam do que não entendem e comparam ozempic com anabolizantes. Semaglutida reduz em 20% o risco cardiovascular em não-diabéticos (https://t.co/LLXCjvBjC7) e 26% em diabéticos (https://t.co/JaZf1zneSW) https://t.co/TxPQqef8UV
@Abo_Yasser1993 تفضل المصادر https://t.co/LntZ4TNeoy https://t.co/RmphgdzT1M https://t.co/taxi9jL0En https://t.co/7zFn1W6jCz https://t.co/uDzI9HjNLc
All mentions
Understanding GLP-1 Medications for Type 2 Diabetes
Ever wonder about medications like Trulicity, Ozempic, or Victoza? This video discusses the role of GLP-1 in managing blood glucose levels, how these medications function, their benefits, and potential side effects…
Ozempic causes weight loss. Does it cause hair loss?
Impact of Ozempic, Wegovy, and Mounjaro on Body Composition
This video analyzes the impact of Ozempic, Wegovy, and Mounjaro on body composition. These GLP-1 receptor agonists have shown impressive efficacy in weight loss and altering body composition in individuals with type 2…
Quantos quilos se perde com o Ozempic?
Current Advances in Atrial Fibrillation Treatment and Endurance Athlete Cardiac Risks
This week in cardiology discusses the VENTOUX study on endurance athletes and arrhythmias, the ongoing debate between rate and rhythm control in atrial fibrillation, and the role of GLP1 drugs. The importance of…
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This week’s podcast reviews significant trials including NOAH-AFNET 6 and ARTESiA that highlight the role of direct oral anticoagulants (DOACs) in preventing ischemic stroke among patients with device-detected atrial…
Ozempic and Semaglutide: Effects, Risks, and Future of Weight Loss
In this video, I break down what Ozempic semaglutide really does and its impact on health, including antiaging and fat-burning effects. We explore side effects like pancreatitis and retinopathy, plus future treatments…
Semaglutide's Cardiovascular Safety and Effects in Type 2 Diabetes
This week in cardiology, we discuss coronary CTA, semaglutide for type 2 diabetes, and upcoming cardiology events. Semaglutide showed cardiovascular benefits in a recent study, but requires monitoring for retinopathy…
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
RT @edgarvlermamd: Effects of Once-Weekly
Effects of Once-Weekly
Effects of Once-Weekly Semaglutide #Nephpearls #Cardiorenal #NephSky
Effects of Once-Weekly Semaglutide #Nephpearls #Cardiorenal #VisualAbstract by @AnjanaGopal9 @kidney_boy @brian_rifkin FLOW
Marso SP, Bain SC, et al. “Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes“. N Engl J Med. 2016;375(19):1834-1844. - https://t.co/dygefqG1rI
RETINOPATÍA DIABÉTICA (1/2) ❌ - La noticia la menciona como complicación, pero el prospecto habla de EMPEORAMIENTO si RD previa + insulina - Hallazgo en ensayo de no-inferioridad de resultados
@tehseenp Yes there are side effects and needs to be monitored closely. https://t.co/n1I3JXUtWs https://t.co/r508EbK1xT https://t.co/ickuubZa43
PIONEER 6 Investigators. Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. N Engl J Med. 2019 Aug 29;381(9):841-851. doi: 10.1056/NEJMoa1901118. Epub 2019 Jun 11. PMID: 31185157. https://t.co/DcznGmn23E
NEJM Group’s Dr. Lauren Westafer talks with Dr. Darren McGuire about his group’s trial on oral semaglutide and cardiovascular outcomes in patients with type 2 diabetes who have increased cardiovascular risk. https://t.co/c5nEtE3bfG #ACC25 @LWestafer https://t.co/GsIavbfNYG
@MaelstromCap @kevinnbass "Rates of retinopathy complications (vitreous hemorrhage, blindness, or conditions requiring treatment with an intravitreal agent or photocoagulation) were significantly higher (hazard ratio, 1.76)... " What a great drug. You read your study yeah? https://t.co/bjviNF0SiT
@jsjr0313 @mqyxf @memeticsisyphus semaglutide* is a GLP1 analogue, “semaglutides” are not a thing. It has been proven by clinical studies to improve cardiovascular outcomes. Not saying you shouldn’t exercise if you use it of course. But you’re not right. https://t.co/ehIOfGujxv
@UrgentKarr @jackmurphylive @FitFounder How about you read the cardiovascular outcomes studies in actual humans (non-diabetics and diabetics)? https://t.co/2QfrIf22at https://t.co/34DfC0vd8h
@FitFounder Link to actual human studies: In diabetics: https://t.co/34DfC0vd8h In non-diabetics: https://t.co/2QfrIf22at
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
@fivehundredpou1 @MdBreathe Lots that needs to change. Concerned with emphasis on pharmacological solutions only. Need longer study of GLP-1s. The reductions (.3/100 for stroke, for ex) don't justify the massive push. Cardiovascular: https://t.co/8tk1ghNpxa Stroke: https://t.co/jkCXDO6v6u https://t.co/lUOh5XMfCf
Links Included in Briefing: Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes: https://t.co/rqX4giyteM Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: https://t.co/6mmrAYKPp7
Once weekly semaglutide and cardiovascular outcomes in patients with type 2 diabetes and heart failure with reduced left ventricular ejection fraction #REC https://t.co/nTQB1Hg3c2
https://t.co/iKUZXlq85n SUSTAIN6 での解析でも 腎症の新規発症率、悪化率はセマグルチド群で有意に低いのに、網膜症に関連した合併症の発生率は、セマグルチド群で有意に多く認めらた(3.0% vs. 1.8%, ハザード比:1.76, 95%CI : 1.11~2.78、P=0.02) これに関しては別試験で検証中とは思われる https://t.co/rTkczzXcPU
RT @joaumdoistres: Como sempre, os leigos falam do que não entendem e comparam ozempic com anabolizantes. Semaglutida reduz em 20% o risco…
Como sempre, os leigos falam do que não entendem e comparam ozempic com anabolizantes. Semaglutida reduz em 20% o risco cardiovascular em não-diabéticos (https://t.co/LLXCjvBjC7) e 26% em diabéticos (https://t.co/JaZf1zneSW) https://t.co/TxPQqef8UV
@hankgreen the articles that these graphs are from, for reference: https://t.co/IYDA1Vl2U9 https://t.co/7tCNxdabSR
RT @RevEspCardiol: Once weekly semaglutide and cardiovascular outcomes in patients with type 2 diabetes and heart failure with reduced left…
Once weekly semaglutide and cardiovascular outcomes in patients with type 2 diabetes and heart failure with reduced left ventricular ejection fraction #REC #AOP @belmonte_dr @InfoUMA @_ibima @HRegionalMalaga @CIBER_CV @RGomezHuelgas @MRBernalLopez https://t.co/5CPksDZu7y
@zfawx0 @QuisitiveInvest https://t.co/Lj7ekVtKyb
SEMAGLUTIDE AND CARDIOVASCULAR OUTCOMES IN PATIENTS WITH TYPE 2 DIABETES (SUSTAIN-6 TRIAL) https://t.co/XfJZ9lq6a5
@a_h_ghoneem (Background: #Ozempic ❤️ protection driven by nonfatal stroke, https://t.co/JBa1526kWi whereas liraglutide's was driven by fatal MI, https://t.co/1IWK2n9HHX ) 6/ https://t.co/XDOlj5m20y
SUSTAIN-6でセマグルチド群で網膜症増加したことを受けてのメタ解析。 https://t.co/aSTsMP9lwv https://t.co/1ZgBrfdrCN https://t.co/G13jDz2Dav
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 DM | NEJM The rate of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke was significantly lower among patients receiving #semaglutide https://t.co/z9ikways5K https://t.co/fZDuM3kWqh
RT @kidney_boy: Here are the adverse events from SUSTAIN-6. Balanced SAEs and no signal for pancreatitis. https://t.co/4lX3PyIqO5 https://…
RT @kidney_boy: Here are the adverse events from SUSTAIN-6. Balanced SAEs and no signal for pancreatitis. https://t.co/4lX3PyIqO5 https://…
Here are the adverse events from SUSTAIN-6. Balanced SAEs and no signal for pancreatitis. https://www.nejm.org/doi/10.1056/NEJMoa1607141
Here are the adverse events from SUSTAIN-6. Balanced SAEs and no signal for pancreatitis. https://t.co/4lX3PyIqO5 https://t.co/wUFB2GziHR
This randomized, double-blind, placebo controlled study was published in New England Journal of Medicine in 2016. 3/3 original article: https://t.co/v0bev3g5Yn
@DanielJDrucker @CaloriesProper @jerryteixeira @sguyenet @gerdosi @garytaubes @DrEades @davidludwigmd The long form of the study. https://t.co/2Ur41odcp4
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
@KaladinFree Ozempic is good for the heart. Maybe trump should be considering. https://t.co/P9rSgxo3nA
RT @DrKarlNadolsky: @ZaherToumi C/w the trials! https://t.co/2VbOrrthMQ https://t.co/caxaVY7wny
@ZaherToumi C/w the trials! https://t.co/2VbOrrthMQ https://t.co/caxaVY7wny
@MichaelAlbertMD @DrNadolsky From cvot & meta-analyses this is pretty consistent https://t.co/caxaVY7wny https://t.co/2VbOrrthMQ
セマグルチドのエビデンス調べてるんですが、ちょっとよくわかんなくて困ってます。 セマグルチドが0.5mgでも1mgでもどっちでもいいのか知りたいんですが、本文中は0.5mg+1mgではPrimary outcomesは有意差あるけど、Appendixでは0.5mgも1mgも有意差ないんですがなぜですか? https://t.co/u1XzHtoWik https://t.co/w1j8E52flf
In a recent meta-analysis there was a 17% reduction in fatal and non-fatal stroke #Semaglutide leads the pack with 35% reduced stroke risk in the SUSTAIN-6 trial مراجع الدراسات: https://t.co/7zFn1W6jCz https://t.co/18vqYp03EK https://t.co/B6a04XEJBc
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
RT @sguyenet: Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. C…
Novo Nordisk reports that semaglutide 2.4 mg reduced cardiovascular events by 20% in ppl with obesity in the SELECT trial. Context: This is the third RCT to show CV event reduction with sema. https://t.co/1gvqimJ3Hm https://t.co/oTQfAhNe79 https://t.co/dLsjoqY7Ns
Should have included reference to both Sustain-6 https://t.co/Ims4Mg8ukC and LEADER: https://t.co/7TgR0eLuLu
@matthewherper It is really that surprising based on these results? https://t.co/7TgR0eLuLu https://t.co/Ims4Mg8ukC
RT @CMichaelGibson: These data in non-diabetics, builds upon previously published data in diabetics showing a 26% reduction in cardiovascul…
... typ 2-diabetes som är en rejäl riskfaktor, om än att de var större (96,7 kg i snittingångsvikt mot 92,1 kg i Sustain-6) och fick en högre dos semaglutid. Läs mer om Sustain-6 här: https://t.co/iXXzc721dX
@ThierryBorgeat Die Daten sind wissenschaftlich nix neues. Die relative Risikoreduktion für vaskuläre Ereignisse unter Semaglutid liegt bei 20-30%. Der Effekt ist nicht dosisabhängig (schon 2016: https://t.co/zkc95epc7o). Neue Indikation führt aber zu neuem Patentschutz im jeweiligen Bereich.
These data in non-diabetics, builds upon previously published data in diabetics showing a 26% reduction in cardiovascular outcomes https://t.co/WIQ8vsok1B https://t.co/CmjwKWh8O8
@DrRyanPDaly @MichaelAlbertMD There's already evidence that semaglutide reduces cardiovascular events comparably to statins in people with T2DM. https://t.co/oTQfAhNe79 https://t.co/dLsjoqY7Ns
@b01dface https://t.co/elfdtzn88p
@guy84179559 @Citrini7 @KlendathuCap It would seem not. https://t.co/IPxACNu8Jd
RT @raphaels7: * CORRECTION 6-20 bpm⬆️is for dual agonists, not semgalutide 1mg semaglutide⬆️heart rate 2.47 bpm above that of the placeb…
RT @raphaels7: * CORRECTION 6-20 bpm⬆️is for dual agonists, not semgalutide 1mg semaglutide⬆️heart rate 2.47 bpm above that of the placeb…
RT @raphaels7: * CORRECTION 6-20 bpm⬆️is for dual agonists, not semgalutide 1mg semaglutide⬆️heart rate 2.47 bpm above that of the placeb…
RT @raphaels7: * CORRECTION 6-20 bpm⬆️is for dual agonists, not semgalutide 1mg semaglutide⬆️heart rate 2.47 bpm above that of the placeb…
RT @raphaels7: * CORRECTION 6-20 bpm⬆️is for dual agonists, not semgalutide 1mg semaglutide⬆️heart rate 2.47 bpm above that of the placeb…
RT @raphaels7: * CORRECTION 6-20 bpm⬆️is for dual agonists, not semgalutide 1mg semaglutide⬆️heart rate 2.47 bpm above that of the placeb…
* CORRECTION 6-20 bpm⬆️is for dual agonists, not semgalutide 1mg semaglutide⬆️heart rate 2.47 bpm above that of the placebo group's https://t.co/TAgV1dYiJp (Table S10) 0.5mg semaglutide⬆️2 BPM, so 2.5mg semaglutide may⬆️> 4-5 bpm "resting heart rate is a predictor of
RT @Dr_Lama_Amer: @Abo_Yasser1993 تفضل المصادر https://t.co/LntZ4TNeoy https://t.co/RmphgdzT1M https://t.co/taxi9jL0En https://t.co/7z…
@Abo_Yasser1993 تفضل المصادر https://t.co/LntZ4TNeoy https://t.co/RmphgdzT1M https://t.co/taxi9jL0En https://t.co/7zFn1W6jCz https://t.co/uDzI9HjNLc
And we have the SUSTAIN-6 CVOT for semaglutide 1.0 (Ozempic) but not sema 2.4 (Wegovy), which showed #CVD benefit driven by a ↓ in stroke https://t.co/Ipe1CLssj1 3/
RT @drjoharji1: @TaibMoh12386758 دواء اوزمبيك في دراسة sustain 6 استطاع تقليل فرص حصول جلطات دماغية بنسبة ٣٩٪ مقارنة بالبلاسيبو https://t.c…
@TaibMoh12386758 دواء اوزمبيك في دراسة sustain 6 استطاع تقليل فرص حصول جلطات دماغية بنسبة ٣٩٪ مقارنة بالبلاسيبو https://t.co/prt53Lkwmu + جرعة واحدة في الاسبوع + لايوجد خطورة هبوط في السكر + تحكم ممتاز في السكر
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @JhannaCueto: Se han publicados diferentes estudios mostrando la seguridad cardiovascular y prevención de eventos en población de riesgo…
RT @JhannaCueto: Se han publicados diferentes estudios mostrando la seguridad cardiovascular y prevención de eventos en población de riesgo…
RT @JhannaCueto: Se han publicados diferentes estudios mostrando la seguridad cardiovascular y prevención de eventos en población de riesgo…
Se han publicados diferentes estudios mostrando la seguridad cardiovascular y prevención de eventos en población de riesgo
RT @drscottyk: Another reason to prescribe GLP1’s: Sustain6 CV trial showed semaglutide (0.5 or 1 mg) reduced CV death, MI or stroke vs pl…
RT @drscottyk: Another reason to prescribe GLP1’s: Sustain6 CV trial showed semaglutide (0.5 or 1 mg) reduced CV death, MI or stroke vs pl…
RT @drscottyk: Another reason to prescribe GLP1’s: Sustain6 CV trial showed semaglutide (0.5 or 1 mg) reduced CV death, MI or stroke vs pl…
RT @drscottyk: Another reason to prescribe GLP1’s: Sustain6 CV trial showed semaglutide (0.5 or 1 mg) reduced CV death, MI or stroke vs pl…
RT @drscottyk: Another reason to prescribe GLP1’s: Sustain6 CV trial showed semaglutide (0.5 or 1 mg) reduced CV death, MI or stroke vs pl…
Another reason to prescribe GLP1’s: Sustain6 CV trial showed semaglutide (0.5 or 1 mg) reduced CV death, MI or stroke vs placebo (2.3% ARR, RR 26%, NNT 43) at 2 years in high risk patients with diabetes. https://t.co/mJH0ILTKh1
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @drscottyk: GLP1’s are incredible! The Sustain 6CV trial showed semaglutide (0.5 or 1 mg)⬇️CV death, MI or stroke vs placebo (2.3% ARR,…
RT @drscottyk: GLP1’s are incredible! The Sustain 6CV trial showed semaglutide (0.5 or 1 mg)⬇️CV death, MI or stroke vs placebo (2.3% ARR,…
RT @drscottyk: GLP1’s are incredible! The Sustain 6CV trial showed semaglutide (0.5 or 1 mg)⬇️CV death, MI or stroke vs placebo (2.3% ARR,…
RT @drscottyk: GLP1’s are incredible! The Sustain 6CV trial showed semaglutide (0.5 or 1 mg)⬇️CV death, MI or stroke vs placebo (2.3% ARR,…
GLP1’s are incredible! The Sustain 6CV trial showed semaglutide (0.5 or 1 mg)⬇️CV death, MI or stroke vs placebo (2.3% ARR, RR 26%, NNT 43) at 2yrs in ⬆️risk patients with DM. Looking forward to SELECT trial results (sema 2.4 mg CV outcome trial in⬆️BMI) https://t.co/mJH0ILTKh1
24c)
Husain M et al. Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. @NEJM 2019. View the summary here: https://t.co/JCHWGlF9IM
It is still 2016 Less than 4 months after LEADER, SUSTAIN-6 comes. Semaglutide, another GLP-1 receptor agonist, shows to ⬇️ the composite outcome of stroke/myocardial infarction/cardiovascular death pts with T2D and⬆️ CV risk! SUSTAIN-6 https://t.co/J1YrLm0tb7 (8/13)
@MichaelAlbertMD
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes | NEJM https://t.co/lXeazVTECi
In many other studies, drugs proved to have the same impressive and unexpected benefits. https://t.co/TqtU2tjpJX https://t.co/Ff9utEIhxR
Lots of people especially in the fitness industry up in arms, that medication isn’t the answer etc... However, semaglutide is showing real positive benefits around appetite suppression and its effects as a whole on CVD risk. https://t.co/iogIEvsHCS
With me so far? Proper management of blood sugar—coupled with hunger suppression—is likely responsible for Semaglutide’s lowering of metabolic & heart risk factors (eg, blood pressure, HbA1c, cholesterol, triglycerides) + *secondary* weight loss effect. 7️⃣ https://t.co/DniDqLAFEy
@Plasmacellguy @Ultracardiodoc @skathire Well this is a good Rex for diabetes that reduces CV events, so I’m not sure what you are worried about. https://t.co/eWnxUG5vYr
@KCKlatt @Hogwood_AC @ProfBatterhamMD @BrownAdey @KevinH_PhD @BioLayne Lower dose but CVD event benefit https://t.co/biZMQfFHrR
Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes Facebook:https://t.co/HMxlBrjB97 Youtube :https://t.co/SyUqiPCRv8
https://t.co/AhWtOdVpnY
Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/GSD9U1Z0uq
Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes , LINK VIDEO: https://t.co/1O9ekwufqw
https://t.co/YkPGSAzrF1
GLP-1受容体作動薬の心血管エビデンス一覧2 ・リキセナチド(商品名リキスミア) ELIXA https://t.co/xuafQgvrFE ・セマグルチド(商品名オゼンピック) SUSTAIN 6 https://t.co/GbRauHohsf PIONEER 6(経口) https://t.co/DcznGmE55E ・アルビグルチド(日本非発売) HARMONY OUTCOMES
@FrogHarmless Always possible. But to date, the most notable health-related side effect is a substantial reduction in cardiovascular event risk in people with T2DM. https://t.co/bJgJqI9ABh
9/ Weight loss was also prominent with semaglutide (as high as 6kg or 13lbs). Maximal effect on glycemia is reached ~10-16wks after starting treatment. Weight loss plateau is reached after ~10wks. N Engl J Med 2016; 375:1834-1844 DOI:10.1056/NEJMoa1607141 ⬇️ https://t.co/N66BMBNlJA
Para hoy jueves refrescamos este artículo del mes pasado de @NEJM Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes Disponible en: https://t.co/g3CYDkWxeb
SUSTAIN6 CVOT https://t.co/HmqdU9w1ir
RT @FarmaMadridAP: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes via @NEJM https://t.co/mjG7ikfb7r
RT @FarmaMadridAP: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes via @NEJM https://t.co/mjG7ikfb7r
RT @FarmaMadridAP: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes via @NEJM https://t.co/mjG7ikfb7r
Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes via @NEJM https://t.co/mjG7ikfb7r
PIONEER 6 Trial Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/jLHVJMtbYb https://t.co/Zf65V5o7o8
@JuanPeirano Los GLP1-RA tienen efecto demostrado de la disminución de MACE https://t.co/lNPaeOF8iT https://t.co/Mt9yLDpQlX
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
2型糖尿病患者における経口セマグルチドと心血管転帰 Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes. M. Husain and Others. N Engl J Med 2019; 381:841-851. https://t.co/B8EiDYWyTd
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
Oral #Semaglutide and #Cardiovascular Outcomes in Patients with Type 2 #Diabetes | #NEJM https://t.co/5EyJmwKrxu
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes | NEJM https://t.co/bQuSFrPUy0
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
RT @NEJM: #VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.…
#VisualAbstract: Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes https://t.co/FuAPUe1QVJ https://t.co/vfSvtmms4a
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
@AnilMakam @VPrasadMDMPH Yet Anil we have many DM2 meds , but we have NO other diabetes medications that can, with behavioural support, generate a mean weight loss of 18+ percent at one year. And also with + Cardiovascular safety https://t.co/kBG0tLXkfo in non-inferiority study https://t.co/nQ9Sb4YgqL
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @skathire: An oral drug which: 1. leads to meaningful weight loss 2. lowers all-cause mortality ~50% 3. lowers CV mortality 4. lowers hg…
RT @RpratleyMD: Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes | NEJM https://t.co/YKHeUdNFIT #ADA2019
Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes | NEJM https://t.co/WTmOOp1kms
RT @RpratleyMD: Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes | NEJM https://t.co/YKHeUdNFIT #ADA2019
RT @RpratleyMD: Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes | NEJM https://t.co/YKHeUdNFIT #ADA2019
RT @RpratleyMD: Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes | NEJM https://t.co/YKHeUdNFIT #ADA2019
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