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J Physiol January 2017 PMID 27641441

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration.

Timothy G Dinan, John F Cryan

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Mentions

48
Peak: 5 in Feb 2023
across 6 sources since Jan 2019

Extended reach

92,198
potential audience

Total likes

1,884

Video views

21,333

Mentions per month

Jan 2019 – Feb 2025

Where it's discussed

  • X / Twitter17 posts
  • Facebook14 posts
  • YouTube6 videos
  • News5 articles
  • Reddit3 posts
  • Blogs3 articles

AI synopsis

What people are saying

The collective discussions reveal a strong interest in the microbiota's role in brain development and aging, exemplified by posts emphasizing therapeutic potentials like probiotics and microbiota transplants, and commentary on the microbiome's influence on diseases. The tone and choice of words like 'awesome review' and references to interdisciplinary research indicate a high level of engagement and perceived importance.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, with many referencing the importance of microbiota in brain health and aging.

InterestHigh interest

Posts display high curiosity, especially when highlighting new therapies or connections to diseases like Alzheimer's and Parkinson's.

EngagementHigh engagement

Comments show deep involvement through sharing additional research, mentioning specific mechanisms like microglia regulation, and discussing practical implications.

ImpactModerate impact

The discussions suggest that the publication could influence future research directions and treatment approaches, though some posts remain speculative.

Abstract in brief

  • The gut-brain axis involves communication between the microbiota and the brain through pathways like nerve signals, hormones, immune responses, and microbial metabolites, which influence brain development, aging, and neurodegenerative diseases.
  • Early life factors such as antibiotics, lack of breastfeeding, stress, and delivery mode can disrupt microbiota composition, potentially affecting long-term health, behavior, and susceptibility to disorders.
  • Changes in gut microbiota are linked to various neurological and psychiatric conditions like depression, autism, and Parkinson's disease, and future treatments may include microbiota-targeted therapies like probiotics, antibiotics, or microbiota transplants.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Luana Chagas
@luanachagas_phd · X

Really awesome review from @jfcryan group, specially for those working with development like #labplas. https://t.co/JfVM43Ozsj

Feb 8, 2023 · 13 likes · 5 shares · 413 followers View post →
Carolyn
@Carolyn53613826 · X

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration. https://t.co/X2YceIZhre

Dec 15, 2021 · 2 likes · 1 followers View post →
Meri Perkins
@mlperk1 · X

https://t.co/1ucvTyI59t

Jan 31, 2025 · 1 like · 1,300 followers View post →
Kenda Rigdon, Ph.D.
@KendaRigdon · X

@follo_India @Mari_Byndloss @vanhatilator @Psychobiotic This is the review from 2017 that I saved on the topic: DOI: 10.1113/JP273106 Looks like gut diversity and Bifido both decrease as we age.

Jan 25, 2019 · 1 like · 722 followers View post →
John F. Cryan
@jfcryan · X

RT @luanachagas_phd: Really awesome review from @jfcryan group, specially for those working with development like #labplas. https://t.co/Jf…

Feb 8, 2023 · 5 shares · 22,441 followers View post →
Sento Segarra
@SentoSegarra · X

¿Por Qué hay tanto REVUELO con los PROBIÓTICOS? 3 Poderosos BENEFICIOS https://t.co/50QW3O0k6L #salud #youtube #sentosegarra

Oct 4, 2024 · 13,787 followers View post →

All mentions

Meri Perkins
@mlperk1 · X

@SabinehazanMD I thought this paper was interesting: https://t.co/mw8VFqA329 started here: any good ? https://t.co/1ucvTyI59t

Jan 31, 2025 · 1,300 followers View post →
Meri Perkins
@mlperk1 · X

https://t.co/1ucvTyI59t

Jan 31, 2025 · 1 like · 1,300 followers View post →
Sento Segarra
@SentoSegarra · X

¿Por Qué hay tanto REVUELO con los PROBIÓTICOS? 3 Poderosos BENEFICIOS https://t.co/50QW3O0k6L #salud #youtube #sentosegarra

Oct 4, 2024 · 13,787 followers View post →
Javi Ciborro
@papayaykware · X

https://t.co/01HmvGIUIY Instintos intestinales: la microbiota como regulador clave del desarrollo cerebral, el envejecimiento y la neurodegeneración

Nov 19, 2023 · 8,041 followers View post →
Iona
@Iona__K4213 · X

RT @luanachagas_phd: Really awesome review from @jfcryan group, specially for those working with development like #labplas. https://t.co/Jf…

Sep 3, 2023 · 5 shares · 30 followers View post →
Dr. Nauf AlBendar | #DOHaD
@thewombeffect · X

RT @luanachagas_phd: Really awesome review from @jfcryan group, specially for those working with development like #labplas. https://t.co/Jf…

Feb 9, 2023 · 5 shares · 617 followers View post →
Armando Ribeiro
@Armando_Ribeiro · X

RT @luanachagas_phd: Really awesome review from @jfcryan group, specially for those working with development like #labplas. https://t.co/Jf…

Feb 8, 2023 · 5 shares · 5,053 followers View post →
Pedgastro
@Isa_CasasG · X

RT @luanachagas_phd: Really awesome review from @jfcryan group, specially for those working with development like #labplas. https://t.co/Jf…

Feb 8, 2023 · 5 shares · 2,432 followers View post →
John F. Cryan
@jfcryan · X

RT @luanachagas_phd: Really awesome review from @jfcryan group, specially for those working with development like #labplas. https://t.co/Jf…

Feb 8, 2023 · 5 shares · 22,441 followers View post →
Luana Chagas
@luanachagas_phd · X

Really awesome review from @jfcryan group, specially for those working with development like #labplas. https://t.co/JfVM43Ozsj

Feb 8, 2023 · 13 likes · 5 shares · 413 followers View post →
Dr P C Dubey
@pcdubey2007 · X

https://t.co/ViTlBDyiRg

Jan 5, 2023 · 671 followers View post →
Carolyn
@Carolyn53613826 · X

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration. https://t.co/X2YceIZhre

Dec 15, 2021 · 2 likes · 1 followers View post →
For health-promoting environments
@SilkeLeFay · X

#Alzheimers #Parkinsons #dementia #neuroscience #publichealth #microbiome #inflammation #COVID19 #longCOVID #agedcare #nutrition #mentalhealth #microglia #amyloid #carehomes #homecare #primarycare #nursing #stress #NCDs #vagus #HRV #smartwatch #health https://t.co/hznJCLT3ay https://t.co/lDPkpNgeKE

Mar 29, 2021 · 4,600 followers View post →
For health-promoting environments
@SilkeLeFay · X

@medical_xpress @NatureComms . Microglia activation is under constant regulation by the gut microbiome. The patient needs a biodynamic fresh vegetable diet, probiotics, movement and slow wave sleep that improve glymphatic/lymphatic drainage, removing toxic waste products. https://t.co/F4KT9r68DR https://t.co/qD87KlG9J8

Aug 21, 2019 · 4,600 followers View post →
For health-promoting environments
@SilkeLeFay · X

. #dementia #Alzheimers #Parkinsons Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration https://t.co/F4KT9r68DR - chronic stress, trauma - healthy fats (nuts, olive oil, some coconut oil) - Pesticides, antibiotics, NSAIDs, diet . https://t.co/XuRNcnYtDa

Aug 15, 2019 · 4,600 followers View post →
lishan
@DrLSChiu · X

motor neuron disease (https://t.co/HHkuTEnGoV), and a whole heap of other neuro- things (https://t.co/zJMSAfweZd, https://t.co/PqGE6rur8q, https://t.co/raxWy4e9O7). It's all pretty crazy, but also opens up a whole other avenue of interdisciplinary investigation. (hello, me)

Mar 17, 2019 · 199 followers View post →
Kenda Rigdon, Ph.D.
@KendaRigdon · X

@follo_India @Mari_Byndloss @vanhatilator @Psychobiotic This is the review from 2017 that I saved on the topic: DOI: 10.1113/JP273106 Looks like gut diversity and Bifido both decrease as we age.

Jan 25, 2019 · 1 like · 722 followers View post →