The adverse effects of an excessive folic acid intake.

Abstract in brief

• Folic acid is essential for many bodily functions and helps prevent neural tube defects, leading some countries to fortify foods like grains, which often results in people consuming more than the recommended amount.
• While folate is generally considered safe, excessive intake of synthetic folic acid through supplements or fortification might cause adverse effects, but scientific studies on this topic have shown mixed results, creating uncertainty about the risks.
• This review aims to summarize current evidence on high folic acid consumption and its potential negative effects on specific population groups, highlighting the need for clearer guidelines and awareness about overconsumption.]