J Mol Med (Berl) March 2017 PMID 27847966

Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation.

Ming-Jer Hsieh, Hsien-Ta Liu, Chao-Nin Wang, Hsiu-Yun Huang, Yuling Lin, Yu-Shien Ko, Jong-Shyan Wang, Vincent Hung-Shu Chang, Jong-Hwei S Pang

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Mentions

65
Peak: 15 in Dec 2021
across 4 sources since Dec 2021

Extended reach

1,502,475
potential audience

Total likes

10,710

Video views

939,506

Mentions per month

Dec 2021 – Jul 2025

Where it's discussed

  • News32 articles
  • X / Twitter29 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reflect a cautious optimism about BPC-157's healing abilities, with posts mentioning its potential to accelerate recovery from vascular damage and improve blood vessel function, exemplified by phrases like 'tons of healing potential' and suggestions for further research, which show a blend of personal interest and scientific curiosity.

AgreementModerate agreement

Most discussions support the positive potential of BPC-157 in healing and vascular repair, indicating general agreement with the publication's findings.

InterestModerate interest

Participants are moderately interested, with many comments contemplating applications for health conditions and calling for further research.

EngagementModerate engagement

Comments go beyond surface-level remarks, referencing mechanisms, anecdotal experiences, and suggestions for future studies.

ImpactModerate impact

There is a recognition that BPC-157 could influence healing therapies, especially for vascular and connective tissue conditions, suggesting a moderate perceived impact.

Abstract in brief

  • BPC 157 is a pentadecapeptide that has shown potential in promoting angiogenesis, which is the formation of new blood vessels, through various assays and experiments.
  • The study demonstrated that BPC 157 increases blood vessel density and accelerates blood flow recovery in ischemic conditions in rat hind limbs while enhancing the expression and activity of vascular endothelial growth factor receptor 2 (VEGFR2).
  • The therapeutic effects of BPC 157 are linked to its ability to promote VEGFR2 internalization and activate the VEGFR2-Akt-eNOS signaling pathway, leading to improved angiogenesis.

Top posts

Most liked on X and Bluesky
Jeffrey Lubell (EDS, ME/CFS, LongCOVID Research)
@JeffLubell_C19 · X

Among other research, I would like to see research on whether BPC-157 and other healing peptides can accelerate the healing of endothelial damage. https://t.co/10bxmp1Kx8 21/

Dec 18, 2021 · 62 likes · 8 shares · 3,596 followers View post →
Jeffrey Lubell (EDS, ME/CFS, LongCOVID Research)
@JeffLubell_C19 · X

One possibility that merits further research is that that peptide BPC-157 helps accelerate healing of endothelial damage. This could be one mechanism through which this peptide helps people with #MECFS. https://t.co/10bxmp1Kx8

Dec 16, 2021 · 15 likes · 3 shares · 3,596 followers View post →
BowTiedNeuron | Neuroscientist
@BowTiedNeuron · X

Citations: 1. https://t.co/GT5L69DX96 2. https://t.co/Rs2lldbpgJ 3. https://t.co/5ZoFrnYddU 4. https://t.co/A17cViDA4G 5. https://t.co/oj9zQdg6dp 6. https://t.co/GqMJx3Y8ei 7. https://t.co/ENEBrlYzWA 8. https://t.co/ceinA2HmlR 9. https://t.co/GjCN8hyvW0 10.

Oct 6, 2024 · 8 likes · 3 shares · 12,855 followers View post →
John Goldman ☀️
@johngoldman_ · X

BPC 157 has a ton of healing potential. It's helped me a lot! Here are a few highlights. Thread: 1) BPC 157 increase angiogenesis, or the formation of new blood vessels and accelerates blow flow recovery, which in turn promotes healing. https://t.co/gxrHf4sdnA.

Aug 17, 2023 · 7 likes · 3 shares · 120,165 followers View post →
Jeffrey Lubell (EDS, ME/CFS, LongCOVID Research)
@JeffLubell_C19 · X

@ahandvanish @ElianaUku @ar_pnw I would suggest looking at BPC-157 as a mechanism for accelerating recovery from vascular damage, which I believe is central to certain phenotypes of #MECFS and #LongCovid. https://t.co/10bxmp1Kx8

Apr 7, 2023 · 5 likes · 3,596 followers View post →
Jeffrey Lubell (EDS, ME/CFS, LongCOVID Research)
@JeffLubell_C19 · X

@VioletaQSmith There are anecdotal reports that people with ME/CFS benefit from BPC-157. BPC-157 has been shown to promote endothelial tube formation. And leakage from blood vessels appears central to lipedema. I need to study this more. https://t.co/tUiG3RO5Y6.

Dec 5, 2021 · 2 likes · 3,596 followers View post →

All mentions

Richard
@PGC1a_RB · X

RT @BowTiedNeuron: Citations: 1. https://t.co/GT5L69DX96 2. https://t.co/Rs2lldbpgJ 3. https://t.co/5ZoFrnYddU 4. https://t.co/A17cViDA4G 5…

Oct 6, 2024 · 3 shares · 14,855 followers View post →
Robert Sapolsky's Burner
@sapolskysburner · X

RT @BowTiedNeuron: Citations: 1. https://t.co/GT5L69DX96 2. https://t.co/Rs2lldbpgJ 3. https://t.co/5ZoFrnYddU 4. https://t.co/A17cViDA4G 5…

Oct 6, 2024 · 3 shares · 901 followers View post →
BowTiedNeuron | Neuroscientist
@BowTiedNeuron · X

Citations: 1. https://t.co/GT5L69DX96 2. https://t.co/Rs2lldbpgJ 3. https://t.co/5ZoFrnYddU 4. https://t.co/A17cViDA4G 5. https://t.co/oj9zQdg6dp 6. https://t.co/GqMJx3Y8ei 7. https://t.co/ENEBrlYzWA 8. https://t.co/ceinA2HmlR 9. https://t.co/GjCN8hyvW0 10.

Oct 6, 2024 · 8 likes · 3 shares · 12,855 followers View post →
Robert Sapolsky's Burner
@sapolskysburner · X

RT @IchorGrad: 1) https://t.co/dcXtYkAnVD 2) https://t.co/0hG2bBXEJM

Aug 15, 2024 · 1 share · 901 followers View post →
Ichor Grad Student
@IchorGrad · X

1) https://t.co/dcXtYkAnVD 2) https://t.co/0hG2bBXEJM

Jan 16, 2024 · 2 likes · 1 share · 2,732 followers View post →
Garrett Smith
@xkit · X

https://t.co/BLYEYstemi https://t.co/aRE4sXOi60 The lyophilized (freeze dried) products last for months. Source: @PeptideScience https://t.co/r6t5uiWypc

Nov 8, 2023 · 1,859 followers View post →
John Goldman ☀️
@johngoldman_ · X

Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation https://t.co/PoAoaimz0z

Sep 20, 2023 · 120,165 followers View post →
maximum_Q™
@maximum_Q · X

RT @jackmurphylive: BPC 157 has a ton of healing potential. It's helped me a lot! Here are a few highlights. Thread: 1) BPC 157 increase…

Aug 30, 2023 · 3 shares · 24,698 followers View post →
John Goldman ☀️
@johngoldman_ · X

RT @jackmurphylive: BPC 157 has a ton of healing potential. It's helped me a lot! Here are a few highlights. Thread: 1) BPC 157 increase…

Aug 30, 2023 · 3 shares · 120,165 followers View post →
Richard
@PGC1a_RB · X

RT @jackmurphylive: BPC 157 has a ton of healing potential. It's helped me a lot! Here are a few highlights. Thread: 1) BPC 157 increase…

Aug 17, 2023 · 3 shares · 14,855 followers View post →
John Goldman ☀️
@johngoldman_ · X

BPC 157 has a ton of healing potential. It's helped me a lot! Here are a few highlights. Thread: 1) BPC 157 increase angiogenesis, or the formation of new blood vessels and accelerates blow flow recovery, which in turn promotes healing. https://t.co/gxrHf4sdnA.

Aug 17, 2023 · 7 likes · 3 shares · 120,165 followers View post →
Jeffrey Lubell (EDS, ME/CFS, LongCOVID Research)
@JeffLubell_C19 · X

@ahandvanish @ElianaUku @ar_pnw I would suggest looking at BPC-157 as a mechanism for accelerating recovery from vascular damage, which I believe is central to certain phenotypes of #MECFS and #LongCovid. https://t.co/10bxmp1Kx8

Apr 7, 2023 · 5 likes · 3,596 followers View post →
Sneaky Peeks
@PeeksSneaky · X

RT @JeffLubell_C19: Among other research, I would like to see research on whether BPC-157 and other healing peptides can accelerate the hea…

Dec 12, 2022 · 8 shares · 478 followers View post →
Jeffrey Lubell (EDS, ME/CFS, LongCOVID Research)
@JeffLubell_C19 · X

@ItsAngInLA More research is needed into whether peptides like BPC-157 can help with vascular healing. It seems to have helped my daughter. https://t.co/10bxmp1Kx8

Jan 25, 2022 · 1 like · 3,596 followers View post →
Juan Penaloza
@J_P_28 · X

RT @JeffLubell_C19: Among other research, I would like to see research on whether BPC-157 and other healing peptides can accelerate the hea…

Dec 19, 2021 · 8 shares · 1,744 followers View post →
theNabster #Doom #Gloom
@meNabster · X

RT @JeffLubell_C19: Among other research, I would like to see research on whether BPC-157 and other healing peptides can accelerate the hea…

Dec 19, 2021 · 8 shares · 29,154 followers View post →
Nabil H The Peacemaker ⚛️☮️
@inabster · X

RT @JeffLubell_C19: Among other research, I would like to see research on whether BPC-157 and other healing peptides can accelerate the hea…

Dec 19, 2021 · 8 shares · 37,968 followers View post →
Dame Sa
@LongCovidHell · X

RT @JeffLubell_C19: Among other research, I would like to see research on whether BPC-157 and other healing peptides can accelerate the hea…

Dec 18, 2021 · 8 shares · 10,278 followers View post →
franmurrell @franmurrell@franmurrell@toad.social
@franmurrell1 · X

RT @JeffLubell_C19: Among other research, I would like to see research on whether BPC-157 and other healing peptides can accelerate the hea…

Dec 18, 2021 · 8 shares · 1,175 followers View post →
monique d'hooghe ♿ (they, she)
@moniquedhooghe · X

RT @JeffLubell_C19: Among other research, I would like to see research on whether BPC-157 and other healing peptides can accelerate the hea…

Dec 18, 2021 · 8 shares · 3,498 followers View post →
Frank T. Lofaro Jr.
@queensnycfrank · X

RT @JeffLubell_C19: Among other research, I would like to see research on whether BPC-157 and other healing peptides can accelerate the hea…

Dec 18, 2021 · 8 shares · 1,191 followers View post →
Jeffrey Lubell (EDS, ME/CFS, LongCOVID Research)
@JeffLubell_C19 · X

Among other research, I would like to see research on whether BPC-157 and other healing peptides can accelerate the healing of endothelial damage. https://t.co/10bxmp1Kx8 21/

Dec 18, 2021 · 62 likes · 8 shares · 3,596 followers View post →
Dr Melanie
@MelanieWeckert · X

RT @JeffLubell_C19: @exceedhergrasp1 @Dakota_150 We need research on how to accelerate healing of endothelial damage to reduce leakages fro…

Dec 18, 2021 · 1 share · 11,268 followers View post →
Jeffrey Lubell (EDS, ME/CFS, LongCOVID Research)
@JeffLubell_C19 · X

@exceedhergrasp1 @Dakota_150 We need research on how to accelerate healing of endothelial damage to reduce leakages from microangiopathic blood vessels and improve lymphatic system function. I wonder if this is the mechanism through which BPC-157 and others healing peptides help #pwME https://t.co/10bxmp1Kx8

Dec 17, 2021 · 2 likes · 1 share · 3,596 followers View post →
Dr Alison Twycross RN
@alitwy · X

RT @JeffLubell_C19: One possibility that merits further research is that that peptide BPC-157 helps accelerate healing of endothelial damag…

Dec 17, 2021 · 3 shares · 5,697 followers View post →
TiredTara
@EndemicPrepared · X

RT @JeffLubell_C19: One possibility that merits further research is that that peptide BPC-157 helps accelerate healing of endothelial damag…

Dec 17, 2021 · 3 shares · 3,856 followers View post →
extrem sommerzeit fan
@darkspookers · X

RT @JeffLubell_C19: One possibility that merits further research is that that peptide BPC-157 helps accelerate healing of endothelial damag…

Dec 16, 2021 · 3 shares · 718 followers View post →
Jeffrey Lubell (EDS, ME/CFS, LongCOVID Research)
@JeffLubell_C19 · X

One possibility that merits further research is that that peptide BPC-157 helps accelerate healing of endothelial damage. This could be one mechanism through which this peptide helps people with #MECFS. https://t.co/10bxmp1Kx8

Dec 16, 2021 · 15 likes · 3 shares · 3,596 followers View post →
Jeffrey Lubell (EDS, ME/CFS, LongCOVID Research)
@JeffLubell_C19 · X

@VioletaQSmith There are anecdotal reports that people with ME/CFS benefit from BPC-157. BPC-157 has been shown to promote endothelial tube formation. And leakage from blood vessels appears central to lipedema. I need to study this more. https://t.co/tUiG3RO5Y6.

Dec 5, 2021 · 2 likes · 3,596 followers View post →