Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lower genetic risk and unhealthy lifestyle. https://t.co/WIdl429WTu
Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease.
Mentions
Extended reach
Total likes
Video views
Mentions per month
Jan 2019 – Jun 2025Where it's discussed
-
News185 articles
-
Facebook134 posts
-
X / Twitter81 posts
-
Blogs22 articles
-
YouTube2 videos
-
Reddit2 posts
-
Bluesky1 posts
AI synopsis
What people are saying
The collective discussions emphasize the significant role of lifestyle factors in mitigating genetic risk for coronary disease, with phrases like 'reduces almost 50%' and 'genetics matter but lifestyle is key' conveying both agreement and impact. The tone ranges from analytical to motivational, highlighting how this research influences clinical practice, public health, and individual choices.
Most discussions strongly support the findings that a healthy lifestyle can significantly reduce coronary disease risk, even for those with high genetic predisposition.
Several posts highlight personal and professional interest, emphasizing the importance of lifestyle in cardiovascular health and referencing studies, which demonstrates high curiosity and engagement.
Many discussions involve analyzing data, sharing examples, and reflecting on clinical practice, indicating moderate to deep engagement with the research implications.
The consensus is that this research has major implications for public health and clinical strategies, as illustrated by comments about reducing risk by up to 50% and references to its potential to change practices.
Abstract in brief
- Both genetic and lifestyle factors influence the risk of developing coronary artery disease (CAD), and this study aimed to assess how a healthy lifestyle can mitigate genetic risk.
- Researchers analyzed data from large cohorts to create a genetic risk profile using a polygenic score and evaluated lifestyle adherence based on factors like smoking, obesity, exercise, and diet.
- Findings revealed that individuals at high genetic risk for CAD can reduce their event risk significantly (by 46%) through a healthy lifestyle, demonstrating that lifestyle choices play a crucial role in preventing coronary events, even for those with a genetic predisposition.
Top posts
Most liked on X and BlueskyIf you have bad genetics, is it even worth trying???
Yesterday, during my Friday afternoon lifestyle discussion with patients, someone said.....doc, the disease runs in my family. I had to open a separate slide deck and show this.@dramitkhera @pnatarajanmd https://t.co/ZkhqvzzVRa https://t.co/Xn0IWqrfPN
remarkable visual illustrating the effect of lifestyle choices (tobacco/BMI/exercise/diet) is at least as impactful as genetics from https://t.co/l0UqUx4cDi https://t.co/wsDJwPnCMK
Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease | NEJM - Among participants at high genetic risk, a favorable lifestyle was associated with a nearly 50% lower relative risk of coronary artery disease than was an unfavorable lifestyle. https://t.co/a5Hd2qRg5r
@DrAnkitKPatel @ShariqShamimMD @doconmoney @AnkurKalraMD @DrMarthaGulati @iamritu @purviparwani @JayMathewsMD @RealKushAgrawal @Uqayyum123 Even if it is genetics, we now have convincing data, that healthy lifestyle will lower CV risk significantly. Hence my saying - If our CV fate is written in our DNA, it for the most part is written in pencil. https://t.co/ZifrzPq6re
All mentions
Iron Deficiency: Vegan vs Meat-Based Diets Explained
Iron deficiency can be influenced by diet. This video examines whether eating meat is necessary for adequate iron intake or if vegan diets can meet those needs effectively.
Healthy Lifestyle Habits Can Extend Life by 7 to 15 Years.
Adopting a healthy lifestyle can add between 7 and 15 years to your lifespan, with factors like strong social relations, not smoking, regular physical activity, balanced diet, healthy weight, and moderate alcohol intake…
Doença cardiovascular: Mesmo quem está no topo do risco genético reduz quase 50% a chance de doença coronária ao manter 3 de 4 hábitos: – não fumar – peso saudável – exercício regular – dieta equilibrada (doi: 10.1056/NEJMoa1605086)
Doença cardiovascular: Mesmo quem está no topo do risco genético reduz quase 50% a chance de doença coronária ao manter 3 de 4 hábitos: – não fumar – peso saudável – exercício regular – dieta equilibrada (doi: 10.1056/NEJMoa1605086)
@BeckerQuintana What about this one? It's from this paper that I think set the stage for this kind of analyses: https://t.co/rWPQCkF1Gs https://t.co/DgoOzfDHEi
@raphaels7 From memory, This study from 8 years ago is as close as we get to understanding genetics vs lifestyle but in mainly caucasian population... https://t.co/LgpAKcOs4O
RT @MAIDEN_MAFLD: https://t.co/5zOXQfGQps
https://t.co/5zOXQfGQps
@ACLifeMed This graph! If healthy lifestyle can do this among individuals with high genetic risk, the possibility of what it can accomplish at a general population level, is what motivated me to make Lifestyle Medicine the core foundation of my practice! https://t.co/ZifrzPq6re https://t.co/IzggWD94jJ
@MossoSanch https://t.co/EYuSDpN57b.)
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
aspetti SOCIALI, SANITARI ed ECONOMICI. Siete obbligati a tenerne contro altrimenti l'onda travolgerà anche le vostre carriere politiche. https://t.co/xiFHDs3ZzJ
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
RT @MichaelAlbertMD: Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lowe…
Individuals with a high genetic risk but a healthy lifestyle are at lower risk of heart disease than those with a lower genetic risk and unhealthy lifestyle. https://t.co/WIdl429WTu
Even if you have a family history of disease, adopting at least 3 out of 4 key lifestyle habits (healthy weight, exercise, no smoking, healthy diet) has been associated with a 50% lower risk of developing #heart disease https://t.co/UXz1sct746
@drjamesdinic For heart disease it seems closer to 50%. Do you have any reference for your statement? https://t.co/3Zpfk2sdpN
"If you change to a healthy lifestyle you can decrease your cardiovascular risk by 50%." @DrOstfeld Check out this article: https://t.co/GDcrUbvQpc
High risk of cardiac disease if it is in your genes. You can reduce the risk by choosing a healthy lifestyle. Link - https://t.co/ZisBnwo2g0 #research #health #cardiac #heart #healthy https://t.co/dUFcPAgjof
RT @davykevinp: I don't if anyone might want to have read but I like this paper Genetic Risk, Adherence to a Healthy Lifestyle, and Corona…
I don't if anyone might want to have read but I like this paper Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease | NEJM https://t.co/yFFwp3FgO9
@Chandle74418127 @tomp729 exactly plenty of work showing 'bad' genetics warrant even more attention to modifiable RFs collect fam history as part of clinical info but don't let it discourage you from lifestyle optimization https://t.co/l0UqUx4cDi
Researchers did an analysis to determine if a healthy lifestyle is associated with a reduced risk of coronary artery disease among people with a high genetic risk. https://t.co/NMM5NNdrqy https://t.co/Gpip769vYD
ทีนี้ก็ลองพิจารณาดูครับ ว่าเราจะโบ้ยให้ Genetic แม่งไปเลย ขี้เกียจคิดขี้เกียจทำอะไรปวดกระบาล หรือจะปรับรูปแบบการใช้ชีวิตของเราเอง ไม่ใช่แค่เรื่องสุขภาพหรอก เรื่องอื่นๆก็เหมือนกัน Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease https://t.co/YdWmwvqmpX
RT @NutritionMadeS3: If you have bad genetics, is it even worth trying???
RT @NutritionMadeS3: If you have bad genetics, is it even worth trying???
If you have bad genetics, is it even worth trying???
@TheBhupiThakur @drmaggarwal https://t.co/ZifrzPHHiM
RT @koro485: Psychiatryではないけれど、これとか。geneを見ていること以外は特に真新しさないし、むしろ身体活動の効果推定は普通の疫学研究より弱めな印象うけるけど。NEJMか。。。 https://t.co/EgiKRhwmeK
@AleksiReito @JusiMD @EevaNyberg @JuhaniKnuuti @KariTikkinen @DuodecimFi @oys2030 @markkumyllykan2 @NevalainenOlli @DrLeinonen @Laakarilehti @Duodecimlehti @yletiede @Kaleva_fi Tässä on minusta hyvä "klassikko", josta elintapojen ja genetiikan "interplay" tulee selkeästi esiin: https://t.co/eddReu0Cds Eli vahvasti yleistäen (jutun fokus on coronary artery disease), olivatpa geenit mitä hyvänsä - terveet elintavat ovat hyvästä
@bnikhil @khurramn1 @amitvkhera @AniruddhPatelMD @AmiBhattMD @AmericanHeartMA @skathire @MGHHeartHealth @broadinstitute @AHAMeetings @dramitkhera @ASPCardio @MedGenomeLabs @miguelcainzos23 @MichaelJBlaha @RonBlankstein @DrMichaelShapir @kershawpatel @DrPJoshi @alka_kanaya @MBittencourtMD @pnatarajanmd @NEJM A Classic by @amitvkhera and colleagues. https://t.co/ZifrzPHHiM
Ever heard of a SNP? Single Nucleotide Polymorphisms
RT @KoushikReddyMD: @DrAnkitKPatel @ShariqShamimMD @doconmoney @AnkurKalraMD @DrMarthaGulati @iamritu @purviparwani @JayMathewsMD @RealKush…
@DrAnkitKPatel @ShariqShamimMD @doconmoney @AnkurKalraMD @DrMarthaGulati @iamritu @purviparwani @JayMathewsMD @RealKushAgrawal @Uqayyum123 Even if it is genetics, we now have convincing data, that healthy lifestyle will lower CV risk significantly. Hence my saying - If our CV fate is written in our DNA, it for the most part is written in pencil. https://t.co/ZifrzPq6re
RT @KoushikReddyMD: @DrMichaelShapir @DrMarthaGulati If our fate is written in our genes, I believe that it's written in pencil! Zip Code>>…
RT @KoushikReddyMD: @DrMichaelShapir @DrMarthaGulati If our fate is written in our genes, I believe that it's written in pencil! Zip Code>>…
@DrMichaelShapir @DrMarthaGulati If our fate is written in our genes, I believe that it's written in pencil! Zip Code>>>Genetic Code! https://t.co/ZifrzPq6re
RT @antonia_winne: Adherence to a healthy lifestyle was associated with a substantially reduced risk of coronary artery disease within each…
Adherence to a healthy lifestyle was associated with a substantially reduced risk of coronary artery disease within each category of genetic risk | NEJM #PRS #medicine https://t.co/Qo4ODF3CQ3
@yourheartdoc1 @mividovich @WSJ Even in the setting of high genetic risk.......https://t.co/ZkhqvzzVRa https://t.co/2r9LLhOpXe
RT @JNovickRD: Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease | NEJM - Among participants at high genetic risk, a fav…
RT @JNovickRD: Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease | NEJM - Among participants at high genetic risk, a fav…
Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease | NEJM - Among participants at high genetic risk, a favorable lifestyle was associated with a nearly 50% lower relative risk of coronary artery disease than was an unfavorable lifestyle. https://t.co/a5Hd2qRg5r
remarkable visual illustrating the effect of lifestyle choices (tobacco/BMI/exercise/diet) is at least as impactful as genetics from https://t.co/l0UqUx4cDi https://t.co/wsDJwPnCMK
RT @KoushikReddyMD: Yesterday, during my Friday afternoon lifestyle discussion with patients, someone said.....doc, the disease runs in my…
RT @KoushikReddyMD: Yesterday, during my Friday afternoon lifestyle discussion with patients, someone said.....doc, the disease runs in my…
RT @KoushikReddyMD: Yesterday, during my Friday afternoon lifestyle discussion with patients, someone said.....doc, the disease runs in my…
RT @KoushikReddyMD: Yesterday, during my Friday afternoon lifestyle discussion with patients, someone said.....doc, the disease runs in my…
RT @KoushikReddyMD: Yesterday, during my Friday afternoon lifestyle discussion with patients, someone said.....doc, the disease runs in my…
RT @KoushikReddyMD: Yesterday, during my Friday afternoon lifestyle discussion with patients, someone said.....doc, the disease runs in my…
RT @KoushikReddyMD: Yesterday, during my Friday afternoon lifestyle discussion with patients, someone said.....doc, the disease runs in my…
@topologic_apple @OZmandia @NathanEqualsOne @nickandre @JTMarlin77 @DaveKeto @KoushikReddyMD @hjluks @EAllen0417 @Common_SenseCO @siobhan_huggins Genetics matter. https://t.co/0olDgmRiRK
Yesterday, during my Friday afternoon lifestyle discussion with patients, someone said.....doc, the disease runs in my family. I had to open a separate slide deck and show this.@dramitkhera @pnatarajanmd https://t.co/ZkhqvzzVRa https://t.co/Xn0IWqrfPN
@DrNadolsky And just like the sail, with effort, we can navigate even through an ocean of high genetic risk and come out as a winner!! https://t.co/ZkhqvzzVRa https://t.co/AWBGbqpLfd
RT @jsenior64: En el día mundial del corazón recuerden esto: tu carga genética define tu riesgo cardiovascular, pero está en tus manos camb…
RT @jsenior64: En el día mundial del corazón recuerden esto: tu carga genética define tu riesgo cardiovascular, pero está en tus manos camb…
RT @jsenior64: En el día mundial del corazón recuerden esto: tu carga genética define tu riesgo cardiovascular, pero está en tus manos camb…
RT @jsenior64: En el día mundial del corazón recuerden esto: tu carga genética define tu riesgo cardiovascular, pero está en tus manos camb…
RT @jsenior64: En el día mundial del corazón recuerden esto: tu carga genética define tu riesgo cardiovascular, pero está en tus manos camb…
RT @jsenior64: En el día mundial del corazón recuerden esto: tu carga genética define tu riesgo cardiovascular, pero está en tus manos camb…
RT @jsenior64: En el día mundial del corazón recuerden esto: tu carga genética define tu riesgo cardiovascular, pero está en tus manos camb…
RT @jsenior64: En el día mundial del corazón recuerden esto: tu carga genética define tu riesgo cardiovascular, pero está en tus manos camb…
RT @JulioBasulto_DN: Buen estilo de vida➜50% ↓ riesgo de enf. coronaria en pers. con alto riesgo genético. N Engl J Med. Khera AV et al. ht…
RT @JulioBasulto_DN: Buen estilo de vida➜50% ↓ riesgo de enf. coronaria en pers. con alto riesgo genético. N Engl J Med. Khera AV et al. ht…
RT @DrMichaelMol: Even if you have a family history of disease, adopting at least 3 out of 4 key lifestyle habits (healthy weight, exercise…
Even if you have a family history of disease, adopting at least 3 out of 4 key lifestyle habits (healthy weight, exercise, no smoking, healthy diet) has been associated with a 50% lower risk of developing #heart disease https://t.co/UXz1sct746
@ElizaWallace27 @Mirage5 @haiderwarraich Even in the setting of high genetic risk, healthy lifestyle can significantly lower the risk of cardiovascular events! As it’s often said, “it’s dinner, not DNA.” :) https://t.co/ZkhqvzzVRa
@markmccarthyoxf @manuelrivascruz Abstract looks familiar
@SGuptaMD @ShariqShamimMD @ethanjweiss @ChristianAssad @bschermd @ErinMichos @venkmurthy @TheVeggieMD Even in the setting on family history and genetic risk, healthy lifestyle has the potential to lower the event rate significantly. https://t.co/ZkhqvzzVRa https://t.co/NgtsNWsOeS
RT @EAllen0417: Almost 20 years since the genome was decoded and not a single genetic treatment is used to treat any common disease. This s…
RT @EAllen0417: Almost 20 years since the genome was decoded and not a single genetic treatment is used to treat any common disease. This s…
Almost 20 years since the genome was decoded and not a single genetic treatment is used to treat any common disease. This suggests that gene are not individually causative in most common disease states. They may create slight increases in risk. https://t.co/TyukUAgK5k https://t.co/L3aJeZ7h0D
@OZmandia @FatEmperor "The trend to value diet, exercise and lifestyle change as superior to medicine only risks providing useless information." You know who they are attacking. "a favorable lifestyle was associated with a nearly 50% lower relative risk" https://t.co/dxvnjX45Ue
RT @JulioBasulto_DN: Buen estilo de vida➜50% ↓ riesgo de enf. coronaria en pers. con alto riesgo genético. N Engl J Med. Khera AV et al. ht…
RT @JulioBasulto_DN: Buen estilo de vida➜50% ↓ riesgo de enf. coronaria en pers. con alto riesgo genético. N Engl J Med. Khera AV et al. ht…
@drjohnm @skathire @venkmurthy @cecilejanssens Even in the setting of high genetic risk, favorable lifestyle can lower CV event rates by 50-60% https://t.co/ZkhqvzzVRa https://t.co/1Ai7866Tyi
MM
GP
KL
JN
DD
MG
DM
RL
M
JS
D
AG
EM
MC
MJ
MT
SD
LY
LZ
DW
DP
EA
DM
C
SS
AC
JB
KD
UR
FF
ᴰ
HC
PK
AF
TM
DP
DG
LM
AW
LG
C
EP
AM
JD
HN
DS
JV
TG
AT
EH
HP
DC
AP
OS
CM
SD
CA
JD
TK
SM
GD
M
DR
YT