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Discussions reveal a focus on the significant protective effects of PCSK9 and HMGCR genetic variants, with posts referencing the reduction in cardiovascular events and the role of LDL levels, while also noting the nuance of increased diabetes risk in some individuals. The tone combines scientific detail with acknowledgment of the research's potential impact, illustrating both curiosity and cautious optimism about these genetic findings.
Most discussions reflect a consensus on the protective effects of genetic variants in PCSK9 and HMGCR on cardiovascular risk, though some mention potential limitations, such as the increased diabetes risk.
Posts show moderate interest, highlighting key findings like LDL reduction and cardiovascular benefits but also noting the nuanced increase in diabetes risk, indicating engagement with the topic's complexity.
Participants reference specific mechanisms, genetics, and research findings, demonstrating a considered engagement with the scientific details rather than superficial discussion.
The dialogues suggest recognition of significant implications for personalized medicine and therapeutics, reinforcing the importance of these genetic insights on disease risk management.
Genetic variants in PCSK9 and HMGCR were associated with nearly identical protective effects on the risk of CV events: each independently produced 19% lower odds for CV events per 10 mg/dL ⬇️in LDL-C level. https://t.co/YngmSMPzpl
@cremieuxrecueil "The lower your LDL for longer, the better your health." Except for more diabetes. https://t.co/AYRggIUxNJ
@BigDDaddyCali @MasalaFry69 @squirrelpalooza @Rizabellepow @ErinGoBragh360 Incorrect. Here is a Mendelain randomization study regarding genetic LDL irrelevant to diet- though accounted for in p value calculations: https://t.co/jIXEiQNWgV And of course the medication trials and studies with mechanisms solely on LDL reduction: https://t.co/XQVaTEa8I9
@MEATritionCom @NutritionMadeS3 https://t.co/k4zbpHi5zu
Bibliografia 43 https://t.co/V2CWAjGQmv Ference, Fazio y Sabatine conocelos aqui: https://t.co/1uz4Aecc0O Similar al 31 Ggenes que bajan LDL via PCSK9 y HMGCR , mejoran eventos y son aditivos Lo que refuerza la hipótesis... Olvidaron mencionar un detalle...
RT @drscottyk: Genetic variants in PCSK9 and HMGCR were associated with nearly identical protective effects on the risk of CV events: each…
In this video, Dr. Sten Ekberg's cholesterol claims are critically analyzed against scientific evidence. Bempedoic acid, an ATP citrate lyase inhibitor, effectively reduces LDL cholesterol with fewer side effects…
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This week's cardiology update covers statins and diabetes, antiarrhythmic drugs in serious heart disease, and latest research on PVC suppression in patients with NICM and ICDs.
@BigDDaddyCali @MasalaFry69 @squirrelpalooza @Rizabellepow @ErinGoBragh360 Incorrect. Here is a Mendelain randomization study regarding genetic LDL irrelevant to diet- though accounted for in p value calculations: https://t.co/jIXEiQNWgV And of course the medication trials and studies with mechanisms solely on LDL reduction: https://t.co/XQVaTEa8I9
@cremieuxrecueil "The lower your LDL for longer, the better your health." Except for more diabetes. https://t.co/AYRggIUxNJ
@MEATritionCom @NutritionMadeS3 https://t.co/k4zbpHi5zu
RT @drscottyk: Genetic variants in PCSK9 and HMGCR were associated with nearly identical protective effects on the risk of CV events: each…
RT @drscottyk: Genetic variants in PCSK9 and HMGCR were associated with nearly identical protective effects on the risk of CV events: each…
Genetic variants in PCSK9 and HMGCR were associated with nearly identical protective effects on the risk of CV events: each independently produced 19% lower odds for CV events per 10 mg/dL ⬇️in LDL-C level. https://t.co/YngmSMPzpl
Making the protection against ascvd even more impressive. (The increased risk of diabetes only appears to be in a subset of individuals, btw) https://t.co/UepnuDBPJg https://t.co/VHLNuiuN6I
Bibliografia 43 https://t.co/V2CWAjGQmv Ference, Fazio y Sabatine conocelos aqui: https://t.co/1uz4Aecc0O Similar al 31 Ggenes que bajan LDL via PCSK9 y HMGCR , mejoran eventos y son aditivos Lo que refuerza la hipótesis... Olvidaron mencionar un detalle...