Publications by authors named "Brian A Ference"

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The LDL cumulative exposure hypothesis: evidence and practical applications.
Brian A Ference, Eugene Braunwald, Alberico L Catapano

Nat Rev Cardiol· October 2024

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Frequent questions and responses on the 2022 lipoprotein(a) consensus statement of the European Atherosclerosis Society.
Florian Kronenberg, Samia Mora, Erik S G Stroes, Brian A Ference, Benoit J Arsenault, Lars Berglund, Marc R Dweck, Marlys L Koschinsky, Gilles Lambert, François Mach

June 2023

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Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.
Tom G Richardson, Eleanor Sanderson, Tom M Palmer, Mika Ala-Korpela, Brian A Ference, George Davey Smith, Michael V Holmes

PLoS Med· March 2020

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Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review.
Allan D Sniderman, George Thanassoulis, Tamara Glavinovic, Ann Marie Navar, Michael Pencina, Alberico Catapano, Brian A Ference

December 2019

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Association Between Triglyceride Lowering and Reduction of Cardiovascular Risk Across Multiple Lipid-Lowering Therapeutic Classes: A Systematic Review and Meta-Regression Analysis of Randomized Controlled Trials.
Nicholas A Marston, Robert P Giugliano, KyungAh Im, Michael G Silverman, Michelle L O'Donoghue, Stephen D Wiviott, Brian A Ference, Marc S Sabatine

October 2019

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Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease.
Brian A Ference, John J P Kastelein, Kausik K Ray, Henry N Ginsberg, M John Chapman, Chris J Packard, Ulrich Laufs, Clare Oliver-Williams, Angela M Wood, Adam S Butterworth

JAMA· January 2019

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Impact of Lipids on Cardiovascular Health: JACC Health Promotion Series.
Brian A Ference, Ian Graham, Lale Tokgozoglu, Alberico L Catapano

J Am Coll Cardiol· September 2018

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Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes.
Brian A Ference, Jennifer G Robinson, Robert D Brook, Alberico L Catapano, M John Chapman, David R Neff, Szilard Voros, Robert P Giugliano, George Davey Smith, Sergio Fazio

December 2016

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Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: a Mendelian randomization analysis.
Brian A Ference, Wonsuk Yoo, Issa Alesh, Nitin Mahajan, Karolina K Mirowska, Abhishek Mewada, Joel Kahn, Luis Afonso, Kim Allan Williams, John M Flack

J Am Coll Cardiol· December 2012

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2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias.
François Mach, Konstantinos C Koskinas, Jeanine E Roeters van Lennep, Lale Tokgözoğlu, Lina Badimon, Brian A Ference

Eur Heart J· November 2025

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[2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias].
François Mach, Konstantinos C Koskinas, Jeanine E Roeters van Lennep, Lale Tokgözoğlu, Lina Badimon, Brian A Ference

G Ital Cardiol (Rome)· November 2025

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2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias.
François Mach, Konstantinos C Koskinas, Jeanine E Roeters van Lennep, Lale Tokgözoğlu, Lina Badimon, Brian A Ference

Atherosclerosis· October 2025

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Safety and Efficacy of Obicetrapib in Patients at High Cardiovascular Risk.
Stephen J Nicholls, Adam J Nelson, Marc Ditmarsch, John J P Kastelein, Christie M Ballantyne, Brian A Ference

N Engl J Med· July 2025

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Obicetrapib on top of maximally tolerated lipid-modifying therapies in participants with or at high risk for atherosclerotic cardiovascular disease: rationale and designs of BROADWAY and BROOKLYN.
Stephen J Nicholls, Adam J Nelson, Marc Ditmarsch, John J P Kastelein, Christie M Ballantyne, Brian A Ference

Am Heart J· August 2024

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Exploring apolipoprotein C-III: pathophysiological and pharmacological relevance.
Chris J Packard, Angela Pirillo, Sotirios Tsimikas, Brian A Ference, Alberico L Catapano

Cardiovasc Res· February 2024

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Integrating the Biology of Cardiovascular Disease into the Epidemiology of Economic Decision Modelling via Mendelian Randomisation.
Zanfina Ademi, Jedidiah I Morton, Danny Liew, Stephen J Nicholls, Sophia Zoungas, Brian A Ference

Pharmacoeconomics· November 2022

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Genetic proxies for PCSK9 inhibition associate with lipoprotein(a): Effects on coronary artery disease and ischemic stroke.
Gian Marco De Marchis, Tolga D Dittrich, Rainer Malik, Annaelle V Zietz, Lilian F Kriemler, Brian A Ference

Atherosclerosis· November 2022

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World Heart Federation Cholesterol Roadmap 2022.
Kausik K Ray, Brian A Ference, Tania Séverin, Dirk Blom, Stephen J Nicholls

Glob Heart· November 2022

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Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement.
Florian Kronenberg, Samia Mora, Erik S G Stroes, Brian A Ference, Benoit J Arsenault

Eur Heart J· October 2022

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Population genomic screening of young adults for familial hypercholesterolaemia: a cost-effectiveness analysis.
Clara Marquina, Paul Lacaze, Jane Tiller, Moeen Riaz, Amy C Sturm, Brian A Ference

Eur Heart J· September 2022

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The time is now: Achieving FH paediatric screening across Europe - The Prague Declaration.
Nicole Bedlington, Marianne Abifadel, Birgit Beger, Mafalda Bourbon, Héctor Bueno, Brian A Ference

GMS Health Innov Technol· September 2022

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Interpreting the Clinical Implications of Drug-Target Mendelian Randomization Studies.
Brian A Ference

J Am Coll Cardiol· August 2022

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The Potential Clinical Benefit of Lowering Lipoprotein(a).
Brian A Ference

JAMA· May 2022

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Is the SMART risk prediction model ready for real-world implementation? A validation study in a routine care setting of approximately 380 000 individuals.
Ailsa J McKay, Laura H Gunn, Brian A Ference, Jannick A N Dorresteijn, Gijs F N Berkelmans

Eur J Prev Cardiol· March 2022

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Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society.
Henry N Ginsberg, Chris J Packard, M John Chapman, Jan Borén, Carlos A Aguilar-Salinas, Brian A Ference

Eur Heart J· December 2021

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Using Mendelian Randomization to Improve the Design of Randomized Trials.
Brian A Ference, Michael V Holmes, George Davey Smith

Cold Spring Harb Perspect Med· July 2021

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Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development.
Michael V Holmes, Tom G Richardson, Brian A Ference, Neil M Davies, George Davey Smith

Nat Rev Cardiol· June 2021

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Systematic Coronary Risk Evaluation (SCORE): JACC Focus Seminar 4/8.
Ian M Graham, Emanuele Di Angelantonio, Frank Visseren, Dirk De Bacquer, Brian A Ference

J Am Coll Cardiol· June 2021

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LDL-cholesterol lowering and clinical outcomes in hypercholesterolemic subjects with and without a familial hypercholesterolemia phenotype: Analysis from the secondary prevention 4S trial.
Antonio J Vallejo-Vaz, Chris J Packard, Brian A Ference, Raul D Santos, John J P Kastelein

Atherosclerosis· March 2021

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Asian Pacific Society of Cardiology Consensus Recommendations on Dyslipidaemia.
Natalie Koh, Brian A Ference, Stephen J Nicholls, Ann Marie Navar, Derek P Chew

Eur Cardiol· February 2021

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Update on Lipids and Lipoproteins-Reply.
Brian A Ference, John J P Kastelein, Alberico L Catapano

JAMA· January 2021

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Mendelian Randomization Study of ACLY and Cardiovascular Disease. Reply.
Brian A Ference, Kausik K Ray, Stephen J Nicholls

N Engl J Med· August 2020

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