Curr Top Med Chem July 2017 PMID 28049395

Type 3 Diabetes Mellitus: A Novel Implication of Alzheimers Disease.

Jerzy Leszek, Elzbieta Trypka, Vadim V Tarasov, Ghulam Md Ashraf, Gjumrakch Aliev

Full text PDF Download social card

Mentions

Peak: 3 in Feb 2022

across 2 sources since Feb 2022

Extended reach

286

potential audience

Total likes

Video views

Mentions per month

Feb 2022 – Nov 2024

Where it's discussed

YouTube3 videos
X / Twitter2 posts

AI synopsis

What people are saying

The discussions reflect a basic interest in the connection between insulin resistance and brain health, as exemplified by comments emphasizing factors like overeating and insulin's effects on brain cells. The tone is somewhat confrontational, with references like 'educate yourself' suggesting disagreements and a desire for clarification, which limits the depth of engagement and perceived impact.

AgreementModerate agreement

There is a mild overall agreement with the idea that insulin resistance relates to brain health, as seen in the supportive tone of the comments that link metabolic health to neurodegenerative processes.

InterestModerate interest

The discussions show moderate interest, with participants engaging on the topic of insulin resistance and its role in brain functions, though not deeply exploring the specifics of the publication.

EngagementModerate engagement

Participants exhibit some engagement by referencing related concepts like diet, insulin, and brain health, but the exchange remains relatively superficial and focused on clarifying assertions.

ImpactNeutral impact

The overall impact appears limited; while the discussion touches on relevant medical concepts, it does not seem to influence broader perceptions or demonstrate significant change in understanding.

Abstract in brief

The text describes how Alzheimer's disease (AD) is linked to decreased insulin and insulin receptor expression in the brain, leading to disrupted insulin signaling, brain metabolism issues, and cognitive decline, which resembles type 2 diabetes.
Researchers suggest that AD might actually be a form of neuroendocrine disorder similar to diabetes, leading to the term "Type 3 diabetes mellitus" (T3DM) or "brain diabetes."
The review emphasizes the complexity of this relationship, involving other factors like low-density lipoprotein receptors and advanced glycation end products, and explains why AD is increasingly being called T3DM.]

Read the full abstract