C R Biol February 2017 PMID 28089486

Molecular genetics of human obesity: A comprehensive review.

Rajan Kumar Singh, Permendra Kumar, Kulandaivelu Mahalingam

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Mentions

13
Peak: 2 in Oct 2025
across 3 sources since Apr 2020

Extended reach

148,656
potential audience

Total likes

3,842

Video views

31,380

Mentions per month

Apr 2020 – Oct 2025

Where it's discussed

  • X / Twitter9 posts
  • YouTube3 videos
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions demonstrate strong interest through mentions of pathways like the Melanocortin system and open access papers, with some posts critically engaging with scientific validity, such as emphasizing the need for proper studies. Words like 'comprehensive' and references to 'genetics' highlight the significance placed on this research, indicating an overall moderate impact on advancing understanding of obesity.

AgreementModerate agreement

Most discussions recognize the importance of genetics and scientific research, indicating general agreement on the article's validity.

InterestHigh interest

Posts reference detailed aspects like pathways and open access papers, showing a high level of curiosity and engagement with the topic.

EngagementModerate engagement

Many comments cite specific pathways (e.g., Melanocortin pathway), link studies, and discuss implications, reflecting active engagement.

ImpactModerate impact

The emphasis on genetics' role and references to comprehensive reviews suggest the discussion has moderate influence on understanding obesity's complexity.

Abstract in brief

  • Human obesity is a major health issue worldwide, influenced by genetic factors that affect energy balance and homeostasis through the hypothalamus and signaling molecules.
  • Recent research has identified specific genetic variants responsible for monogenic (single-gene) obesity, as well as additional variants found through genome-wide association studies (GWAS), highlighting the genetic component of obesity.
  • Besides genetics, environmental and epigenetic factors are increasingly recognized as key contributors to obesity, and future research merging clinical findings with molecular genetics is essential for discovering new obesity-related genes and improving interventions.]

Top posts

Most liked on X and Bluesky
Serhat Yildirim
@_SerhatYildirim · X

Los van de kwestie; uw stelling "obesitas is eigen verantwoordelijkheid" is gewoonweg onjuist @PhRoose. Zie: https://t.co/1bzAPmImDH "Genetic (!!!) factors play a crucial role in determining an individual's predisposition to the weight gain and being obese." https://t.co/i5UVv6jJPf

May 30, 2020 · 7 likes · 1,254 followers View post →
Fabián
@Biofab_ · X

Fin Espero que os haya gustado el hilo. Os dejo aquí las referencias https://t.co/q772u6vio0 https://t.co/sxec5961aY https://t.co/9BImxyqviO

Mar 4, 2021 · 5 likes · 831 followers View post →
Aditya Narayan
@DrAditya1996 · X

4️⃣ Molecular Genetics of obesity mainly involves the Melanocortin signalling pathway.

Apr 21, 2023 · 4 likes · 353 followers View post →
Saúl Sánchez
@SaulNutri · X

En primer lugar, la obesidad es un problema multifactorial. Existen condicionantes genéticos y también ambientales.

Jan 31, 2022 · 2 likes · 107,886 followers View post →
jkr PETASSE
@nova_moon_ · X

Oui oui allez, instruit toi donc avec de vraies études scientifiques plutôt que tes stats faites avec ton cul. https://t.co/wGFdmrdZaq https://t.co/JE1gYPDFsY https://t.co/pRpFLHxmBU

Sep 30, 2024 · 2 likes · 1,248 followers View post →
lisaporter2
@LisaPorter2 · X

@BlueObserverA @HeyNurseKat @DrKSouc @TravIsScience @GYamey Dr Soucie linked studies. Reviews are appropriate when there is a sufficient body of literature to summarize. https://t.co/cfPaHc2VFs https://t.co/evvECtgGm1 Also the point of the post was that it is known that body shaming does not help anyone no matter what the etiology.

May 21, 2023 · 1 like · 3,152 followers View post →

All mentions

Biss Lee
@biss.com.br · Bluesky

youtu.be/AFv1vwoaRqs?...

Oct 21, 2025 · 1 like View post →
Leave it to Beaver
@espacetimeNOT · X

(Molecular genetics of human obesity: A comprehensive review ) 2017. open for download

Jan 24, 2025 · 1,198 followers View post →
jkr PETASSE
@nova_moon_ · X

Oui oui allez, instruit toi donc avec de vraies études scientifiques plutôt que tes stats faites avec ton cul. https://t.co/wGFdmrdZaq https://t.co/JE1gYPDFsY https://t.co/pRpFLHxmBU

Sep 30, 2024 · 2 likes · 1,248 followers View post →
lisaporter2
@LisaPorter2 · X

@BlueObserverA @HeyNurseKat @DrKSouc @TravIsScience @GYamey Dr Soucie linked studies. Reviews are appropriate when there is a sufficient body of literature to summarize. https://t.co/cfPaHc2VFs https://t.co/evvECtgGm1 Also the point of the post was that it is known that body shaming does not help anyone no matter what the etiology.

May 21, 2023 · 1 like · 3,152 followers View post →
Aditya Narayan
@DrAditya1996 · X

4️⃣ Molecular Genetics of obesity mainly involves the Melanocortin signalling pathway.

Apr 21, 2023 · 4 likes · 353 followers View post →
Leave it to Beaver
@espacetimeNOT · X

@CJohnsonRx @DianaMIsaacs this looks like the most comprehensive online paper which is open access. https://t.co/25MopysAYJ

Jan 3, 2023 · 1,198 followers View post →
Saúl Sánchez
@SaulNutri · X

En primer lugar, la obesidad es un problema multifactorial. Existen condicionantes genéticos y también ambientales.

Jan 31, 2022 · 2 likes · 107,886 followers View post →
Fabián
@Biofab_ · X

Fin Espero que os haya gustado el hilo. Os dejo aquí las referencias https://t.co/q772u6vio0 https://t.co/sxec5961aY https://t.co/9BImxyqviO

Mar 4, 2021 · 5 likes · 831 followers View post →
Serhat Yildirim
@_SerhatYildirim · X

Los van de kwestie; uw stelling "obesitas is eigen verantwoordelijkheid" is gewoonweg onjuist @PhRoose. Zie: https://t.co/1bzAPmImDH "Genetic (!!!) factors play a crucial role in determining an individual's predisposition to the weight gain and being obese." https://t.co/i5UVv6jJPf

May 30, 2020 · 7 likes · 1,254 followers View post →
Scot B Kolsin M.D. ABOM, ABFM, F-OMA
@ScotKolsinMD · X

@AHealthBlog Here are some actual journal articles discussing the link between #genetics and #obesity. Genetics of Obesity: What have we Learned? https://t.co/nftn02YWJI Molecular genetics of human obesity: A comprehensive review https://t.co/2dUp73hDRj

Apr 2, 2020 · 157 followers View post →