Cochrane Database Syst Rev January 2017 PMID 28093732

Long-term hormone therapy for perimenopausal and postmenopausal women.

Jane Marjoribanks, Cindy Farquhar, Helen Roberts, Anne Lethaby, Jasmine Lee

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Mentions

27
Peak: 7 in Aug 2025
across 5 sources since Aug 2022

Extended reach

69,123
potential audience

Total likes

214

Video views

5,169

Mentions per month

Aug 2022 – Aug 2025

Where it's discussed

  • Facebook10 posts
  • X / Twitter9 posts
  • News4 articles
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reflect skepticism and concern, with some posts accusing officials of misrepresenting evidence, such as calling hormone therapy 'harmful' despite claims of benefits, which indicates a polarized or cautious attitude rather than strong support or engagement with the research findings.

AgreementLow agreement

Most comments question or oppose the publication, highlighting skepticism about its findings and criticizing authorities for potentially misleading information.

InterestLow interest

Discussions show a low level of curiosity, with many comments dismissive or peripheral rather than exploring the research in depth.

EngagementNeutral engagement

Comments are varied but tend to be superficial, with some sharing links or opinions rather than detailed analysis or active debate.

ImpactNeutral impact

The overall influence of these discussions appears limited, with no strong indication of changing opinions or widespread concern.

Abstract in brief

  • Hormone therapy (HT) is commonly used to manage menopausal symptoms and may also help prevent conditions like cardiovascular disease, osteoporosis, and dementia in older women.
  • The review analyzed 22 studies involving over 43,000 women to evaluate the long-term effects of HT (at least 1 year), focusing on outcomes such as mortality, cardiovascular health, cancer, gallbladder disease, fractures, and cognition.
  • Most data come from studies on postmenopausal women with some health issues, mainly over age 60, and there is limited information on the effects of HT in perimenopausal women or healthier younger postmenopausal women.

Top posts

Most liked on X and Bluesky
Prof. Peter C Gøtzsche
@PGtzsche1 · X

FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (see https://t.co/Ak0fkIp0Pj)? https://t.co/PDBQuRD2aF. @SecKennedy, @DrJBhattacharya, @MartyMakary, @cdcgov, @WHO, @NIH.

Aug 2, 2025 · 34 likes · 15 shares · 36,842 followers View post →
Paulo Farber, MD, PhD.
@paulofarber · X

Marjoribanks J et al. Long-term hormone therapy for perimenopausal and postmenopausal women. Cochrane Database Syst Rev. 2017 Jan 17;1(1):CD004143. https://t.co/WFpa85vtV5 +

Jul 15, 2023 · 1 like · 333 followers View post →
sashalatypova.substack.com "Due Diligence and Art"
@sasha_latypova · X

RT @PGtzsche1: FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (s…

Aug 2, 2025 · 15 shares · 24,129 followers View post →
Hanna_PSSD
@hanna_pssd · X

RT @PGtzsche1: FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (s…

Aug 2, 2025 · 15 shares · 1,143 followers View post →
It was never ‘bout a virus
@donotcomply70 · X

RT @PGtzsche1: FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (s…

Aug 2, 2025 · 15 shares · 1,071 followers View post →
David Earl
@RlDwd39968 · X

RT @PGtzsche1: FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (s…

Aug 2, 2025 · 15 shares · 108 followers View post →

All mentions

Gma2349
@gma2349 · X

RT @PGtzsche1: FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (s…

Aug 2, 2025 · 15 shares · 58 followers View post →
sashalatypova.substack.com "Due Diligence and Art"
@sasha_latypova · X

RT @PGtzsche1: FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (s…

Aug 2, 2025 · 15 shares · 24,129 followers View post →
Darek Bo
@DarekBo1 · X

RT @PGtzsche1: FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (s…

Aug 2, 2025 · 15 shares · 27 followers View post →
Hanna_PSSD
@hanna_pssd · X

RT @PGtzsche1: FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (s…

Aug 2, 2025 · 15 shares · 1,143 followers View post →
It was never ‘bout a virus
@donotcomply70 · X

RT @PGtzsche1: FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (s…

Aug 2, 2025 · 15 shares · 1,071 followers View post →
David Earl
@RlDwd39968 · X

RT @PGtzsche1: FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (s…

Aug 2, 2025 · 15 shares · 108 followers View post →
Prof. Peter C Gøtzsche
@PGtzsche1 · X

FDA’s commissioner @MartyMakary has become a drug rep saying hormone replacement therapy is beneficial when it is harmful (see https://t.co/Ak0fkIp0Pj)? https://t.co/PDBQuRD2aF. @SecKennedy, @DrJBhattacharya, @MartyMakary, @cdcgov, @WHO, @NIH.

Aug 2, 2025 · 34 likes · 15 shares · 36,842 followers View post →
Paulo Farber, MD, PhD.
@paulofarber · X

Marjoribanks J et al. Long-term hormone therapy for perimenopausal and postmenopausal women. Cochrane Database Syst Rev. 2017 Jan 17;1(1):CD004143. https://t.co/WFpa85vtV5 +

Jul 15, 2023 · 1 like · 333 followers View post →
Doeintheheadlights
@Angrymum22Anne · X

@pash22 @BarneyCalman @PharmRJ @KarenMagraith https://t.co/mhjPahTO3c this is more relevant to the discussion.

Aug 27, 2022 · 33 followers View post →