PubHawk
February 2017 PMID 28137860

Creatine maintains intestinal homeostasis and protects against colitis.

Emre Turer, William McAlpine, Kuan-Wen Wang, Tianshi Lu, Xiaohong Li, Miao Tang, Xiaoming Zhan, Tao Wang, Xiaowei Zhan, Chun-Hui Bu, Anne R Murray, Bruce Beutler

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Mentions

22
Peak: 4 in Mar 2022
across 5 sources since Oct 2019

Extended reach

32,735
potential audience

Total likes

204

Video views

24,702

Mentions per month

Oct 2019 – Oct 2025

Where it's discussed

  • Facebook8 posts
  • Reddit6 posts
  • X / Twitter4 posts
  • YouTube3 videos
  • News1 articles

AI synopsis

What people are saying

The discussions primarily involve sharing and endorsing the publication's main conclusion, evident in phrases like 'Creatine maintains intestinal homeostasis and protects against colitis,' which show support and recognition. The tone is straightforward and factual, emphasizing the importance of creatine in gut health, though without detailed analysis or critique, leading to moderate scores in interest and engagement.

AgreementStrong agreement

Both posts reinforce the publication's central finding that creatine is beneficial for intestinal health, showing strong agreement.

InterestModerate interest

There is moderate interest demonstrated by acknowledgment of the study's implications, though it remains somewhat cursory.

EngagementModerate engagement

The discussion reflects basic engagement, simply echoing the findings without deep exploration or critique.

ImpactModerate impact

The posts suggest the research is noteworthy but do not indicate widespread or profound influence beyond basic recognition.

Abstract in brief

  • This study investigates how creatine, a molecule involved in energy production, helps maintain intestinal health by supporting cell energy levels, especially during inflammation like colitis.
  • Researchers identified a specific genetic mutation in mice that increased susceptibility to colitis and found that giving these mice creatine improved their condition, highlighting creatine's protective role.
  • The findings suggest that in cases of intestinal injury, rapid energy replenishment in epithelial cells— facilitated by creatine— is essential for maintaining the gut's mucosal barrier and preventing severe inflammation.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Simone
@SimonePands1111 · X

@ChrisAlvino Creatine maintains intestinal homeostasis and protects against colitis https://t.co/CvlQbok7j0 https://t.co/VlQoOE4GoB

Jun 17, 2025 · 17 likes · 2 shares · 2,729 followers View post →
Create Wellness
@trycreate_co · X

https://t.co/h095fFOa6Q

Apr 5, 2024 · 1 like · 2,417 followers View post →
Simone
@SimonePands1111 · X

RT @SimonePands1111: @ChrisAlvino Creatine maintains intestinal homeostasis and protects against colitis https://t.co/CvlQbok7j0 https://t…

Jun 17, 2025 · 2 shares · 2,729 followers View post →
PRIMESUPPS
@PRIMESUPPSLLC · X

Oct 14, 2025 · 1 followers View post →

All mentions

PRIMESUPPS
@PRIMESUPPSLLC · X

Oct 14, 2025 · 1 followers View post →
Simone
@SimonePands1111 · X

RT @SimonePands1111: @ChrisAlvino Creatine maintains intestinal homeostasis and protects against colitis https://t.co/CvlQbok7j0 https://t…

Jun 17, 2025 · 2 shares · 2,729 followers View post →
Simone
@SimonePands1111 · X

@ChrisAlvino Creatine maintains intestinal homeostasis and protects against colitis https://t.co/CvlQbok7j0 https://t.co/VlQoOE4GoB

Jun 17, 2025 · 17 likes · 2 shares · 2,729 followers View post →
Create Wellness
@trycreate_co · X

https://t.co/h095fFOa6Q

Apr 5, 2024 · 1 like · 2,417 followers View post →
Creatine and mitochondria: Creatine isn't just a muscle supplement ...
Facebook

doi: 10.1073/pnas. 1621400114. [PMID:28137860] · BiKona Ghosh and 22 others. 23 reactions ·. 1 comment. ·. 10 shares. Kristen Lena Pate ...

Oct 9, 2025 View →
Rinse aid in dishwashers linked to epithelial inflammation
Facebook

PNAS.ORG. TET3-mediated DNA oxidation is essential for intestinal ... doi: 10.1073/pnas.1621400114. [PMID:28137860]. BiKona Ghosh and 22 ...

Nov 12, 2024 View →
Does creatine have anti-inflammatory effects?
Facebook

doi: 10.1073/pnas. 1621400114. [PMID:28137860] · BiKona Ghosh and 22 others. 23 reactions ·. 1 comment. ·. 10 shares. En Matal Tee ▻ Health ...

Oct 15, 2024 View →
IBS-D as hyperacidity of the lower GI tract : r/ibs
Reddit

Creatine monohydrate 3 grams daily to provide energy to gut epithelial cells - https://www.pnas.org/doi/10.1073/pnas.1621400114. Taking ...

Mar 19, 2023 View →
Any experience with alternative medicine. : r/UlcerativeColitis
Reddit

... pnas.org/doi/abs/10.1073/pnas.1621400114. There's a few other studies and case reports out there if you search. Honestly though, the evidence ...

Nov 29, 2022 View →
Supplemental creatine is great for your gut : r/SIBO
Reddit

[deleted]. • 4y ago. Comment removed by moderator. virgojeep. OP • 4y ago · https://www.pnas.org/doi/10.1073/pnas.1621400114 · calicobrak. • 3y ...

Mar 14, 2022 View →
La creatina supplementare è ottima per l'intestino. : r/SIBO
Reddit

• 4 anni fa. Commento rimosso da un moderatore. virgojeep. OP • 4 anni fa · https://www.pnas.org/doi/10.1073/pnas.1621400114 · calicobrak. • 3 ...

Mar 14, 2022 View →
补充肌酸对你的肠道有好处: r/SIBO
Reddit

... 外，我在谷歌上找不到什么东西。 virgojeep. 原始发帖人 • 4年前 · https://www.pnas.org/doi/10.1073/pnas.1621400114 · Doct0rStabby. • 4年前.

Mar 14, 2022 View →
Ergänzendes Kreatin ist großartig für Ihren Darm : r/SIBO
Reddit

... Moderator*in entfernt. virgojeep. Poster*in • vor 4 Jahren · https://www.pnas.org/doi/10.1073/pnas.1621400114 · calicobrak. • vor 3 Jahren.

Mar 14, 2022 View →
Nutrients: Creatine in Health and Clinical Disease - Article #12 An ...
Facebook

Proc Natl Acad Sci U S A. 2017 Jan 30. pii: 201621400. doi: 10.1073/pnas.1621400114. [PMID:28137860] · BiKona Ghosh and 22 others ·

Apr 9, 2021 View →
An important source of energy for colonocytes, particularly in the ...
Facebook

doi: 10.1073/pnas. 1621400114. [PMID:28137860] · BiKona Ghosh and 22 others. 23 reactions ·. 1 comment. ·. 10 shares. Rishi Joshi ▻ NEET ...

Aug 18, 2020 View →
Another potential benefit of creatine; essential energy for antitumor ...
Facebook

doi: 10.1073/pnas. 1621400114. [PMID:28137860] · BiKona Ghosh and 22 others. 23 reactions ·. 1 comment. ·. 10 shares.

Oct 19, 2019 View →
Gene that protects against inflammatory bowel disease identified ...
News

Proceedings of the National Academy of Sciences, 2017; 201621400 DOI: 10.1073/pnas.1621400114. Cite This Page: MLA; APA; Chicago. UT ...

Feb 1, 2017 View →
An interesting basic science paper. "A Creatine-Driven Substrate ...
Facebook

doi: 10.1073/pnas. 1621400114. [PMID:28137860] · BiKona Ghosh and 22 others. 23 reactions ·. 1 comment. ·. 10 shares. Douglas Kalman ...

Nov 12, 2015 View →
Can creatine worsen colitis symptoms?
Facebook

doi: 10.1073/pnas. 1621400114. [PMID:28137860] · BiKona Ghosh and 22 others. 23 reactions ·. 1 comment. ·. 10 shares. Profile photo of Rick.

Jul 8, 2015 View →