PubHawk
Pharm Res May 2017 PMID 28155076

Non-destructive Determination of Disintegration Time and Dissolution in Immediate Release Tablets by Terahertz Transmission Measurements.

Daniel Markl, Johanna Sauerwein, Daniel J Goodwin, Sander van den Ban, J Axel Zeitler

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Mentions

12
Peak: 9 in Nov 2019
across 3 sources since Nov 2019

Extended reach

10,141
potential audience

Total likes

57

Video views

3,386

Mentions per month

Nov 2019 – Mar 2021

Where it's discussed

  • X / Twitter8 posts
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The discussions include examples like praise for researchers working on terahertz spectroscopy and mentions of efforts to develop real-time, non-destructive dissolution assays, revealing enthusiasm and recognition of the research’s potential. The tone and choice of words such as ‘developing,’ ‘fast,’ and ‘promising’ emphasize a forward-looking perspective and perceived importance of the findings.

AgreementModerate agreement

Most discussions reflected positive recognition of the research's significance, highlighting breakthroughs in non-destructive testing for tablets and emphasizing its potential benefits.

InterestHigh interest

The conversations demonstrate high interest, with multiple mentions of the technology's applications and praise for the researchers' achievements, indicating active engagement with the material.

EngagementModerate engagement

Participants reference specific methods, institutions, and future applications, showing moderate to deep engagement which indicates they are reflecting on its implications beyond surface-level appreciation.

ImpactModerate impact

The enthusiasm for the technology and its potential to transform pharmaceutical manufacturing suggest that the discussions view this research as having a meaningful impact on the industry.

Abstract in brief

  • This study demonstrates that terahertz (THz) transmission measurements can be used nondestructively to predict disintegration time and active ingredient dissolution in commercial tablets, specifically after 15, 20, and 25 minutes.
  • By analyzing 18 batches of tablets produced through various process conditions, researchers found a strong linear correlation between the effective refractive index (n) measured by THz and both disintegration time and dissolution after 15 minutes, outperforming traditional hardness tests.
  • The findings suggest that THz measurements, due to their high penetration power and contactless nature, are promising tools for monitoring key quality attributes during tablet manufacturing without the need for sample destruction.]
Read the full abstract

Top posts

Most liked on X and Bluesky
The PSSRC
@PSSRCNews · X

#PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets During Manufacture @AAPSComms @TeraView @SIPBS_Strath @EPSRC_CMAC @GSK @innovateuk @cebcambridge #pat #qbd #dissolution #terahertz https://t.co/3iUHYXB2jY

Nov 2, 2019 · 12 likes · 9 shares · 514 followers View post →
Terahertz Cambridge
@THzCambridge · X

@Quantumbutadyne presenting latest work on developing #sensor for real time #nondestructive #dissolution assay for #pharmaceutical industry at #PharmSci360 this week - M1330-06-40 Monday 1.30 pm. Link to the #abstract in video description #thzdoesitbetter https://t.co/jGdjRXWvg2

Nov 3, 2019 · 5 likes · 517 followers View post →
StrathPharm&Bio
@SIPBS_Strath · X

RT @PSSRCNews: #PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets…

Nov 2, 2019 · 9 shares · 2,515 followers View post →
Dr Maggie Cunningham
@MagRoseCun · X

RT @PSSRCNews: #PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets…

Nov 3, 2019 · 9 shares · 1,712 followers View post →
Terahertz Cambridge
@THzCambridge · X

RT @PSSRCNews: #PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets…

Nov 2, 2019 · 9 shares · 517 followers View post →
TeraView
@TeraView · X

RT @PSSRCNews: #PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets…

Nov 2, 2019 · 9 shares · 466 followers View post →

All mentions

Najnin Sharmin
@SharminNajnin · X

Great to see one of our senior from @UniEastFinland working at @Cambridge_Uni on Terahertz Spectroscopy Great job @PrinceBawuah...keep it up Non-destructive Porosity Testing Method for Pharmaceutical Tablets Based... https://t.co/PSVd9KZXZc via @YouTube

Nov 4, 2019 · 57 followers View post →
Dr Maggie Cunningham
@MagRoseCun · X

RT @PSSRCNews: #PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets…

Nov 3, 2019 · 9 shares · 1,712 followers View post →
Terahertz Cambridge
@THzCambridge · X

@Quantumbutadyne presenting latest work on developing #sensor for real time #nondestructive #dissolution assay for #pharmaceutical industry at #PharmSci360 this week - M1330-06-40 Monday 1.30 pm. Link to the #abstract in video description #thzdoesitbetter https://t.co/jGdjRXWvg2

Nov 3, 2019 · 5 likes · 517 followers View post →
TeraView
@TeraView · X

RT @PSSRCNews: #PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets…

Nov 2, 2019 · 9 shares · 466 followers View post →
StrathPharm&Bio
@SIPBS_Strath · X

RT @PSSRCNews: #PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets…

Nov 2, 2019 · 9 shares · 2,515 followers View post →
Terahertz Cambridge
@THzCambridge · X

RT @PSSRCNews: #PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets…

Nov 2, 2019 · 9 shares · 517 followers View post →
Daniel Markl
@DanielMarkl · X

RT @PSSRCNews: #PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets…

Nov 2, 2019 · 9 shares · 350 followers View post →
The PSSRC
@PSSRCNews · X

#PharmSci360 Poster M1330-06-40 on Monday, 4 Nov: Developing a Fast, Non-Destructive Terahertz Dissolution Assay of Tablets During Manufacture @AAPSComms @TeraView @SIPBS_Strath @EPSRC_CMAC @GSK @innovateuk @cebcambridge #pat #qbd #dissolution #terahertz https://t.co/3iUHYXB2jY

Nov 2, 2019 · 12 likes · 9 shares · 514 followers View post →