https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https://t.co/2gtbBds0IL
Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena.
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Mar 2019 – Oct 2025Where it's discussed
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X / Twitter123 posts
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AI synopsis
What people are saying
The overall tone indicates engagement with the article's nuanced explanation of how exercise can both increase and decrease pain through central nervous system mechanisms, as seen in references to recent reviews, research articles, and clinical implications. Words like 'good read', 'great review', and mentions of CNS mechanisms reflect a moderate interest level and recognition of the article's importance in advancing understanding of pain modulation.
Most discussions acknowledge the complexity of exercise's effects on pain, with some emphasizing its dual role in increasing and decreasing pain, aligning with the article's balanced view.
The discussions demonstrate moderate interest, with some posts sharing recent research articles and insights into central mechanisms, but lacking deep technical engagement.
Several posts reference research findings and emphasize the importance of understanding CNS mechanisms, indicating active engagement, but there’s little detailed analysis or debate.
The posts suggest that the publication influences clinical perspectives and research priorities, highlighting its significance in informing pain management practices.
Abstract in brief
- Exercise is widely used to help manage chronic musculoskeletal pain conditions like fibromyalgia and low back pain, and research supports its effectiveness.
- However, exercise can also sometimes increase pain, which can make sticking to rehab programs difficult; animal studies suggest this may be due to central nervous system changes, such as increased activity of NMDA receptors.
- The body's response to exercise involves both pain-increasing mechanisms and pain-relieving pathways, including central inhibitory systems mediated by opioids, serotonin, and NMDA receptors in areas like the rostral ventromedial medulla.]
Top posts
Most liked on X and BlueskyOur recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is on the cover showing the cerebellum - Purkinje. Free access at link below. https://t.co/RTQd4SF4zj #painscience @Exerciseworks @UIowaPTRS https://t.co/d7iygxCITg
Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We propose there is a balance between inhibition & excitation in the central nervous system that determines whether exercise will promote analgesia or promote pain https://t.co/2DE4c1NkCV
✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
@JeremyLewisPT @Retlouping @marklaslett_NZ As you well know Jeremy there is no evidence directly on FS as this is a woefully under research condition. But there is some research on exercises effects on chronic pain, such as this good read https://t.co/B9uoXJax95
Exercise and “top-down” control of pain. Great review of CNS mechanisms will help inform clinical decisions for better use of exercise for pain management. Lima - 2017 - The Journal of Physiology - Wiley Online Library https://t.co/Gl1QhcQWiO
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Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/ulMeA8BdKO
RT @CorKinetic: https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https…
RT @CorKinetic: https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https…
RT @CorKinetic: https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https…
RT @CorKinetic: https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https…
RT @CorKinetic: https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https…
RT @CorKinetic: https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https…
RT @CorKinetic: https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https…
RT @CorKinetic: https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https…
RT @CorKinetic: https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https…
https://t.co/MGLlOTlv7D "Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena" https://t.co/2gtbBds0IL
@ozecaeogui @reumalho hoje em dia temos uma base de literatura mostrando o potencial do exercício atuar nas vias de modulação de dor do SNC: https://t.co/XnDcCC89ee
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
RT @Retlouping: Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We pro…
Does exercise increase or decrease pain? Central mechanisms underlying these two phenomena https://t.co/BZ2WxPZ2uK We propose there is a balance between inhibition & excitation in the central nervous system that determines whether exercise will promote analgesia or promote pain https://t.co/2DE4c1NkCV
RT @DerekGriffin86: ✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
RT @DerekGriffin86: ✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
RT @DerekGriffin86: ✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
RT @DerekGriffin86: ✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
RT @DerekGriffin86: ✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
RT @DerekGriffin86: ✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
RT @DerekGriffin86: ✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
RT @DerekGriffin86: ✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
RT @DerekGriffin86: ✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
✅Keep it simple ✅Doesn't have to be fatiguing (not the aim) ✅Consistency & gradual progression more important
RT @AdamMeakins: @JeremyLewisPT @Retlouping @marklaslett_NZ As you well know Jeremy there is no evidence directly on FS as this is a woeful…
RT @AdamMeakins: @JeremyLewisPT @Retlouping @marklaslett_NZ As you well know Jeremy there is no evidence directly on FS as this is a woeful…
@JeremyLewisPT @Retlouping @marklaslett_NZ As you well know Jeremy there is no evidence directly on FS as this is a woefully under research condition. But there is some research on exercises effects on chronic pain, such as this good read https://t.co/B9uoXJax95
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @Judi_Hunter: Exercise and “top-down” control of pain. Great review of CNS mechanisms will help inform clinical decisions for better us…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
Exercise and “top-down” control of pain. Great review of CNS mechanisms will help inform clinical decisions for better use of exercise for pain management. Lima - 2017 - The Journal of Physiology - Wiley Online Library https://t.co/Gl1QhcQWiO
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
RT @ksluka0101: Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is…
Our recent review article on exercise-induced pain and analgesia published in @JPhysiol is a #Top20Article. My painting is on the cover showing the cerebellum - Purkinje. Free access at link below. https://t.co/RTQd4SF4zj #painscience @Exerciseworks @UIowaPTRS https://t.co/d7iygxCITg
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
RT @DerekGriffin86: An acute exacerbation of pain is a common response to exercise in people with persistent pain. It is important that pat…
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