J Alzheimers Dis May 2018 PMID 28527218

The Mechanisms of Action of Curcumin in Alzheimer's Disease.

Mengxi Tang, Changiz Taghibiglou

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Mentions

Peak: 2 in Sep 2020

across 4 sources since May 2020

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162,624

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2,322

Mentions per month

May 2020 – May 2023

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AI synopsis

What people are saying

The overall tone shows enthusiasm about curcumin's potential, with comments like 'fundamentally important' and calls to 'support further research,' demonstrating recognition of the article's scientific significance. The use of technical terms, such as 'bioavailability' and 'metals like copper,' indicates engagement with the article's detailed mechanisms, while expressions of skepticism and calls for evidence suggest a moderate impact of the publication within the discussion community.

AgreementModerate agreement

Most discussions recognize the potential benefits of curcumin in Alzheimer's treatment, supporting its mechanisms highlighted in the publication.

InterestHigh interest

The discussions reflect high interest, with participants showing curiosity about the therapeutic aspects and limitations of curcumin.

EngagementModerate engagement

Comments include references to scientific concepts like amyloid plaques and bioavailability, indicating a moderate level of engagement and understanding.

ImpactModerate impact

Participants seem to acknowledge the publication’s importance in advancing AD research, although some call for further evidence or clarification.

Abstract in brief

This review explores how curcumin, a compound from turmeric, may help treat Alzheimer's disease (AD) by targeting various aspects of the disease's pathology, such as reducing amyloid plaques, preventing tau hyperphosphorylation, and promoting clearance of harmful proteins.
Curcumin also interacts with metals like copper, lowers cholesterol, influences immune cells in the brain, inhibits enzymes like acetylcholinesterase, and acts as an antioxidant, all of which could slow or modify disease progression.
Despite its promising effects, curcumin's therapeutic potential is limited by its low bioavailability, but overcoming this obstacle could lead to new, effective treatments for AD in the future.

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endocrinorosero

@endocrinorosero · X

@marce_marce2021 @jsenior64 Puedes leer un poco: Tang M, Taghibiglou C. The Mechanisms of Action of Curcumin in Alzheimer's Disease. J Alzheimers Dis. 2017;58(4):1003-1016. doi:10.3233/JAD-170188

May 17, 2023 · 160,180 followers View post →

Santino

@alexandermestri · X

@sp5xx @participedoclub https://t.co/OPfPZmDhaO https://t.co/6iPOUrw2qi https://t.co/AfGzENwJeB https://t.co/lKEuoxYdz9 https://t.co/qDrGwHREBt https://t.co/mA0iJEz2Pf https://t.co/QPwLLGJM1u Antes de afirmar algo, fundamente.

Mar 15, 2023 · 60 followers View post →

kobi Diets

@kobi28531389 · X

Sep 18, 2020 · 2 likes · 62 followers View post →