PubHawk
Physiol Rev July 2017 PMID 28539434

Estrogens in Male Physiology.

Paul S Cooke, Manjunatha K Nanjappa, CheMyong Ko, Gail S Prins, Rex A Hess

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Mentions

24
Peak: 2 in Jan 2023
across 5 sources since Jan 2021

Extended reach

89,586
potential audience

Total likes

431

Video views

28,436

Mentions per month

Jan 2021 – Jul 2025

Where it's discussed

  • X / Twitter14 posts
  • YouTube3 videos
  • News3 articles
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The discussions reflect strong interest and agreement with the idea that estrogen plays vital roles in male health, as shown by phrases like 'crucial roles in male physiology' and 'hormonal importance.' The tone varies from supportive to critical, with some posts emphasizing the scientific complexity, thus demonstrating engagement and potential influence on public understanding.

AgreementModerate agreement

Most discussions acknowledge the importance of hormones like estrogen in male physiology, supporting the article's premise.

InterestHigh interest

There is high curiosity about the role of estrogen in males, evidenced by mentions of controversy and scientific explanations.

EngagementModerate engagement

Participants reference specific mechanisms and implications, such as hormone functions and health impacts, indicating moderate to deep engagement.

ImpactModerate impact

The discussions highlight a broader understanding and reassessment of gender-related health knowledge, suggesting a moderate influence of the publication on perceptions.

Abstract in brief

  • Estrogens, historically linked to female reproduction, also play crucial roles in male physiology by regulating reproductive and nonreproductive organs through receptors like ESR1, ESR2, and GPER, with measurable levels of estradiol (E2) found in male blood and tissues.
  • Aromatase enzyme, present in Leydig cells and other male organs, converts androgens into estrogens, affecting functions such as ion transport, water reabsorption in the epididymis, and sperm development, with disruptions leading to reproductive issues.
  • Estrogen signaling impacts multiple tissues beyond reproduction, including the brain, bone, heart, and immune system, with receptors like ESR1 and GPER playing critical roles, suggesting that estrogen’s influence in males is broader than traditionally thought and warrants further research.]
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Top posts

Most liked on X and Bluesky
Sophie
@SocialistSauce · X

@Kean28484 @VelvetLandmine @coolaunt2021 @TheGoldenMask5 @LtCassiopeia @CloverSevenLeaf @JonniBoi1421 Oh bless your heart. https://t.co/oq3rDGj2Fw

May 20, 2025 · 6 likes · 2,100 followers View post →
Heretic
@slipkn0t8 · X

@secondchances09 @OsborneInk @KeithOlbermann @PaulStanleyLive Yes dear. You do realise that male testosterone levels are around 10x those found in female people, right? The reverse is also true by the way - males produce oestrogen too (but again in different concentrations to female people)? Right? https://t.co/A0q5mArV2R.

May 1, 2023 · 2 likes · 8,151 followers View post →
Njål Ulfredsson
@ToastLancerGJ · X

@LonesomeGusMc @gabby_lamb2069_ @ExptKnitter @AbortionChat Ok, you want to play silly games, Dr. Fuss? Win silly prizes! Your sperm couldn’t even *swim* without the estrogen your balls produce—without so much as a microgram of soy. https://t.co/XeuOXVGbOs

Dec 21, 2023 · 1 like · 1,342 followers View post →
Lexi
@kiff_gaekkul · X

@enzo_landgraf @ouidontcare @sht33v @anna__online https://t.co/5Dx09UNSRc https://t.co/ED62OqgUY5 https://t.co/vOh9ZVdRTx

Feb 3, 2021 · 1 like · 319 followers View post →
♀️Ana -XX
@ana_iamhuman · X

@RepNancyMace Gender medicine is criminal; it denies all the knowledge and progress made regarding the functioning of hormones, which is crucial and gender-differentiated for proper health, not for changing gender. That's impossible. Teenagers are being scammed.https://t.co/ZYH95eyuHN

Mar 14, 2025 · 43,429 followers View post →
Steve Terra Australis
@TheLamarckian · X

@BernardGaynor Both men and women produce hormones that are viewed as exclusive to the other sex. Women need testosterone otherwise they have brittle bones (osteoporosis). Men produce estrogen. Y chromo has a profound effect. #binary #viveladifférence https://t.co/TMWLmHxQAd

Apr 20, 2022 · 3,277 followers View post →

All mentions

Patriot Psychic
@PatriotPsychic · X

@jsalsman @kevluuk @grok @akaCurt @wrappedaroundme I could do this all day. https://t.co/aMNzIxOa0t. .

Jul 3, 2025 · 147 followers View post →
Sophie
@SocialistSauce · X

@Kean28484 @VelvetLandmine @coolaunt2021 @TheGoldenMask5 @LtCassiopeia @CloverSevenLeaf @JonniBoi1421 Oh bless your heart. https://t.co/oq3rDGj2Fw

May 20, 2025 · 6 likes · 2,100 followers View post →
Flenop
@Flenop · X

@CatherineC1995 @HuggableHedgie @mushycrouton https://t.co/asfyPE8Krq https://t.co/9ucbB405kp

Mar 22, 2025 · 22 followers View post →
♀️Ana -XX
@ana_iamhuman · X

@RepNancyMace Gender medicine is criminal; it denies all the knowledge and progress made regarding the functioning of hormones, which is crucial and gender-differentiated for proper health, not for changing gender. That's impossible. Teenagers are being scammed.https://t.co/ZYH95eyuHN

Mar 14, 2025 · 43,429 followers View post →
The Alberta Socialist
@VoxSocialism · X

@rosepoptosis Also: https://t.co/eBeoKUZcRj

May 28, 2024 · 232 followers View post →
Njål Ulfredsson
@ToastLancerGJ · X

@LonesomeGusMc @gabby_lamb2069_ @ExptKnitter @AbortionChat Ok, you want to play silly games, Dr. Fuss? Win silly prizes! Your sperm couldn’t even *swim* without the estrogen your balls produce—without so much as a microgram of soy. https://t.co/XeuOXVGbOs

Dec 21, 2023 · 1 like · 1,342 followers View post →
EliTheFrog.
@corpseintherain · X

@Absdotmot @BlytheGetsCross @PinkNews Estrogen exposure is a risk factor but it's not a cause there are plenty more risk factors than just that. The only known cause is rapid cell division. Gynecomastia is due to hormone imbalance. Estrogen isn't produced through their fat.https://t.co/UnnRvwZ9uX.

Jun 6, 2023 · 122 followers View post →
Levity
@pauladamkeegan · X

https://t.co/CyZseTksV7

Jun 2, 2023 · 1,425 followers View post →
Heretic
@slipkn0t8 · X

@secondchances09 @OsborneInk @KeithOlbermann @PaulStanleyLive Yes dear. You do realise that male testosterone levels are around 10x those found in female people, right? The reverse is also true by the way - males produce oestrogen too (but again in different concentrations to female people)? Right? https://t.co/A0q5mArV2R.

May 1, 2023 · 2 likes · 8,151 followers View post →
Casper Weiss Bang
@cabang_dk · X

@cprslagelse @StorgaardMikkel Det viser sig vidst at hvis du ikke har estrogen kan du ikke gøre nogen gravid, hvilket jeg troede var en traditionel maskulin karakteristika: source https://t.co/5SvKlCbo4Z https://t.co/ne8ip5QNM4

Apr 5, 2023 · 95 followers View post →
kika
@kikatwt · X

@lise05033604 @Fckurfeelurs @blancadiega5 @halomancer1 @Resistpcsjw @MattWalshBlog this is only a hypothesis, but likely it is because the male body also cyclically produces estrogen like the female body (at the same amounts even), but due to high T and the masking presence of high androgens it has minimal effects. https://t.co/zJ41bsotnh

Sep 10, 2022 · 96 followers View post →
Steve Terra Australis
@TheLamarckian · X

@BernardGaynor Both men and women produce hormones that are viewed as exclusive to the other sex. Women need testosterone otherwise they have brittle bones (osteoporosis). Men produce estrogen. Y chromo has a profound effect. #binary #viveladifférence https://t.co/TMWLmHxQAd

Apr 20, 2022 · 3,277 followers View post →
Cees Timmerman
@ctimmerman17 · X

@actuaLee @kurtistrippled @LoveStopsHatred @MercuryMarte @NaturalTop @Lungbarrow1 @gaytimes Not. I did misread, though. Estrogen is needed for healthy bones and naturally produced from testosterone. https://t.co/pCqSAQzbkF https://t.co/Y6Cs4Ncc4A So lifelong medication is a must for bone density, though perhaps xylitol and a diet help: https://t.co/EeGulc8IlA

Oct 22, 2021 · 394 followers View post →
Lexi
@kiff_gaekkul · X

@enzo_landgraf @ouidontcare @sht33v @anna__online https://t.co/5Dx09UNSRc https://t.co/ED62OqgUY5 https://t.co/vOh9ZVdRTx

Feb 3, 2021 · 1 like · 319 followers View post →