Trials May 2017 PMID 28545508

Open-label versus double-blind placebo treatment in irritable bowel syndrome: study protocol for a randomized controlled trial.

Sarah Ballou, Ted J Kaptchuk, William Hirsch, Judy Nee, Johanna Iturrino, Kathryn T Hall, John M Kelley, Vivian Cheng, Irving Kirsch, Eric Jacobson, Lisa Conboy, Anthony Lembo, Roger B Davis

Mentions

6
Peak: 1 in Feb 2019
across 2 sources since Feb 2019

Extended reach

90,286
potential audience

Total likes

1,310

Video views

47,718

Mentions per month

Feb 2019 – Jun 2024

Where it's discussed

  • X / Twitter4 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions reflect curiosity and support for the study, with remarks such as the 2008 placebo research and its relevance to mainstream treatment, and emphasizing the potential for significant practice changes. The tone suggests engagement with the scientific implications, especially considering the surprising effectiveness of open-label placebos and their broader applications.

AgreementModerate agreement

Most discussions recognize the significance of the study, with some referencing prior research and its implications, indicating general support.

InterestHigh interest

Participants show high curiosity about the study, referencing past studies and considering broader applications.

EngagementModerate engagement

Comments discuss specifics like the effectiveness of open-label placebos and implications for different fields, demonstrating active involvement.

ImpactModerate impact

The discussions highlight the potential influence of the findings on medical and veterinary practices, indicating a moderate perceived impact.

Abstract in brief

  • The study compares open-label placebo (OLP), where patients know they're getting a placebo, with double-blind placebo (DBP), where neither patients nor researchers know who is getting the placebo, in treating irritable bowel syndrome (IBS).
  • Recent research shows that even when patients know they're taking a placebo (OLP), they can still experience symptom relief, challenging traditional beliefs about placebo effects.
  • The study also aims to identify genetic and psychological factors that predict OLP responses and explores patients' personal experiences through interviews, potentially reshaping how healthcare providers use placebo effects ethically to improve symptom management.]

Top posts

Most liked on X and Bluesky
Naomi Harvey PhD #WearAMask
@Naomi_D_Harvey · X

Very interesting study here on the placebo effect, showing that it can still have an impact even when participants are told they're being given the placebo! Important implications for veterinary research where placebo's or controls are lacking https://t.co/8bvHhIc5Pa

Mar 26, 2020 · 2 likes · 16,732 followers View post →
jaynemesis
@jaynemesis · X

@Spongecoinbob There was a study in 2008 on placebo treatments for IBS and it was SO effective that there was a follow-up study on using open-label placebos as a mainstream treatment (literally telling people it's a placebo). https://t.co/HNDDwj6ZGD You have done zero research, clearly.

May 15, 2021 · 16,731 followers View post →
青島周一
@syuichiao89 · X

Open-label versus double-blind placebo treatment in irritable bowel syndrome: study protocol for a randomized controlled trial. - PubMed - NCBI https://t.co/91uLPJDTZk

Feb 6, 2019 · 8,603 followers View post →
QBott
@bott_q · X

@ashtroid22 You have probably already read this, still pretty good. @r_bsal, do you have any thoughts on this? https://t.co/LNRUDomBKn

Sep 7, 2021 · 503 followers View post →

All mentions

QBott
@bott_q · X

@ashtroid22 You have probably already read this, still pretty good. @r_bsal, do you have any thoughts on this? https://t.co/LNRUDomBKn

Sep 7, 2021 · 503 followers View post →
jaynemesis
@jaynemesis · X

@Spongecoinbob There was a study in 2008 on placebo treatments for IBS and it was SO effective that there was a follow-up study on using open-label placebos as a mainstream treatment (literally telling people it's a placebo). https://t.co/HNDDwj6ZGD You have done zero research, clearly.

May 15, 2021 · 16,731 followers View post →
Naomi Harvey PhD #WearAMask
@Naomi_D_Harvey · X

Very interesting study here on the placebo effect, showing that it can still have an impact even when participants are told they're being given the placebo! Important implications for veterinary research where placebo's or controls are lacking https://t.co/8bvHhIc5Pa

Mar 26, 2020 · 2 likes · 16,732 followers View post →
青島周一
@syuichiao89 · X

Open-label versus double-blind placebo treatment in irritable bowel syndrome: study protocol for a randomized controlled trial. - PubMed - NCBI https://t.co/91uLPJDTZk

Feb 6, 2019 · 8,603 followers View post →