Publications by authors named "Irving Kirsch"

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What are the treatment remission, response and extent of improvement rates after up to four trials of antidepressant therapies in real-world depressed patients? A reanalysis of the STAR*D study's patient-level data with fidelity to the original research protocol.
H Edmund Pigott, Thomas Kim, Colin Xu, Irving Kirsch, Jay Amsterdam

BMJ Open· July 2023

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Placebo Effect in the Treatment of Depression and Anxiety.
Irving Kirsch

June 2019

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Altered placebo and drug labeling changes the outcome of episodic migraine attacks.
Slavenka Kam-Hansen, Moshe Jakubowski, John M Kelley, Irving Kirsch, David C Hoaglin, Ted J Kaptchuk, Rami Burstein

Sci Transl Med· January 2014

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Active albuterol or placebo, sham acupuncture, or no intervention in asthma.
Michael E Wechsler, John M Kelley, Ingrid O E Boyd, Stefanie Dutile, Gautham Marigowda, Irving Kirsch, Elliot Israel, Ted J Kaptchuk

N Engl J Med· July 2011

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Placebos without deception: a randomized controlled trial in irritable bowel syndrome.
Ted J Kaptchuk, Elizabeth Friedlander, John M Kelley, M Norma Sanchez, Efi Kokkotou, Joyce P Singer, Magda Kowalczykowski, Franklin G Miller, Irving Kirsch, Anthony J Lembo

December 2010

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Initial severity and antidepressant benefits: a meta-analysis of data submitted to the Food and Drug Administration.
Irving Kirsch, Brett J Deacon, Tania B Huedo-Medina, Alan Scoboria, Thomas J Moore, Blair T Johnson

February 2008

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Large responses to antidepressants or methodological artifacts? A secondary analysis of STAR∗D, a single-arm, open-label, nonindustry antidepressant trial.
Colin Xu, Florian Naudet, Thomas T Kim, Michael P Hengartner, Mark A Horowitz, Irving Kirsch

J Clin Epidemiol· November 2025

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Restoring STAR*D: A RIAT Reanalysis of Medication Augmentation Therapy After Failed SSRI Treatment Using Patient-Level Data with Fidelity to the Original Research Protocol.
Colin Xu, Thomas T Kim, Martin Plöderl, Kevin P Kennedy, Irving Kirsch

medRxiv· October 2025

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Efficacy of open-label placebos for premenstrual syndrome: a randomised controlled trial.
Antje Frey Nascimento, Jens Gaab, Bojana Degen, Mareike Rytz, Anja Holder, Irving Kirsch

BMJ Evid Based Med· March 2025

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Restoring STAR*D: A Reanalysis of Drug-Switch Therapy After Failed SSRI Treatment Using Patient-Level Data with Fidelity to the Original STAR*D Research Protocol.
Colin Xu, Thomas T Kim, Irving Kirsch, Martin Plöderl, Jay D Amsterdam

medRxiv· February 2025

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The risks of adverse events with mirtazapine for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis.
Caroline Barkholt Kamp, Johanne Juul Petersen, Pascal Faltermeier, Sophie Juul, Christina Dam Bjerregaard Sillassen, Irving Kirsch

BMC Psychiatry· January 2025

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Reciprocal relationships between positive expectancies and positive emotions during the COVID-19 pandemic: a cross-lagged panel study.
Petronela Predatu, Daniel David, Irving Kirsch, Stelian Florean, Răzvan Predatu

Psychol Health· December 2024

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A randomized trial investigating the impact of response expectancy on the counting blessings intervention: the role of optimism as a moderator.
Petronela Predatu, Daniel David, Irving Kirsch, Ionuț Stelian Florean, Răzvan Predatu

Front Psychol· December 2024

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Conclusions Regarding the Role of Expectations in Placebo Analgesia Studies May Depend on How We Investigate It: A Meta-Analysis, Systematic Review, and Proposal for Methodological Discussions.
Sigrid Juhl Lunde, Sophie Rosenkjær, Susan Tomczak Matthiesen, Irving Kirsch, Lene Vase

Psychosom Med· September 2024

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Re-thinking the treatment of depression: have we been misinformed about antidepressants? A webinar discussion with Irving Kirsch, Ph.D. and Michael D. Yapko, Ph.D.
Irving Kirsch, Michael D Yapko

Am J Clin Hypn· June 2024

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The relationship between transliminality, hypnotic and imaginative suggestibility, and other personality traits.
Abbie J Irving, Niia Nikolova, Susan Robinson, Iris Ionita, Steve W Kelly, Irving Kirsch

Acta Psychol (Amst)· March 2024

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Beneficial and harmful effects of tricyclic antidepressants for adults with major depressive disorder: a systematic review with meta-analysis and trial sequential analysis.
Caroline Barkholt Kamp, Johanne Juul Petersen, Pascal Faltermeier, Sophie Juul, Faiza Siddiqui, Irving Kirsch

BMJ Ment Health· January 2024

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Placebos in pediatrics: A cross-sectional survey investigating physicians' perspectives.
Vanda Faria, Cameron Talbert, Nathan Goturi, David Borsook, Alyssa Lebel, Irving Kirsch

J Psychosom Res· September 2023

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A qualitative study of imaginary pills and open-label placebos in test anxiety.
Sarah Buergler, Dilan Sezer, Alexander Busch, Marlon Enzmann, Berfin Bakis, Irving Kirsch

PLoS One· September 2023

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Brain-to-brain mechanisms underlying pain empathy and social modulation of pain in the patient-clinician interaction.
Dan-Mikael Ellingsen, Kylie Isenburg, Changjin Jung, Jeungchan Lee, Jessica Gerber, Irving Kirsch

Proc Natl Acad Sci U S A· June 2023

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The risks of adverse events with venlafaxine and mirtazapine versus 'active placebo', placebo, or no intervention for adults with major depressive disorder: a protocol for two separate systematic reviews with meta-analysis and Trial Sequential Analysis.
Caroline Kamp Jørgensen, Sophie Juul, Faiza Siddiqui, Mark Abie Horowitz, Joanna Moncrieff, Irving Kirsch

Syst Rev· March 2023

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Imaginary pills and open-label placebos can reduce test anxiety by means of placebo mechanisms.
Sarah Buergler, Dilan Sezer, Niels Bagge, Irving Kirsch, Cosima Locher

Sci Rep· February 2023

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Clinical hypnosis as a nondeceptive placebo: empirically derived techniques.
Irving Kirsch

Am J Clin Hypn· January 2023

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Remotely Provided Open-Label Placebo Reduces Frequency of and Impairment by Allergic Symptoms.
Tobias Kube, Irving Kirsch, Julia A Glombiewski, Michael Witthöft, Anne-Kathrin Bräscher

Psychosom Med· November 2022

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Can placebos reduce intrusive memories?
Tobias Kube, Irving Kirsch, Julia A Glombiewski, Philipp Herzog

Behav Res Ther· November 2022

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Expectations: How and when do they contribute to placebo analgesia?
Sophie Rosenkjær, Sigrid Juhl Lunde, Irving Kirsch, Lene Vase

Front Psychiatry· September 2022

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The Proposed Task Force Hypnosis Efficacy Guidelines: The Role of Moderation and Mediation in Efficacy Trials.
Guy H Montgomery, Irving Kirsch

Int J Clin Exp Hypn· August 2022

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Response to acute monotherapy for major depressive disorder in randomized, placebo controlled trials submitted to the US Food and Drug Administration: individual participant data analysis.
Marc B Stone, Zimri S Yaseen, Brian J Miller, Kyle Richardville, Shamir N Kalaria, Irving Kirsch

BMJ· August 2022

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Psychological Predictors of Response to Open-Label Versus Double-Blind Placebo in a Randomized Controlled Trial in Irritable Bowel Syndrome.
Sarah Ballou, Julia W Haas, Johanna Iturrino, Judy Nee, Irving Kirsch

Psychosom Med· July 2022

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Music-Induced Analgesia in Healthy Participants Is Associated With Expected Pain Levels but Not Opioid or Dopamine-Dependent Mechanisms.
Sigrid Juhl Lunde, Peter Vuust, Eduardo A Garza-Villarreal, Irving Kirsch, Arne Møller

Front Pain Res (Lausanne)· April 2022

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