Adv Exp Med Biol September 2017 PMID 28585204

Insulin Resistance, Obesity and Lipotoxicity.

Dilek Yazıcı, Havva Sezer

Mentions

7
Peak: 1 in Oct 2022
across 4 sources since Oct 2022

Extended reach

341,226
potential audience

Total likes

6,970

Video views

336,783

Mentions per month

Oct 2022 – Dec 2024

Where it's discussed

  • News3 articles
  • YouTube2 videos
  • X / Twitter1 posts
  • Facebook1 posts

AI synopsis

What people are saying

The group agrees that lipotoxicity contributes to insulin resistance and pancreatic issues, referencing specific processes like lipid signaling and fatty acid utilization. Their tone emphasizes understanding rather than critique, with mentions of 'metabolic alterations' indicating interest in mechanistic details, but overall engagement remains moderate despite acknowledging the importance of these pathways.

AgreementStrong agreement

The discussion clearly aligns with the publication, recognizing the roles of lipotoxicity in insulin resistance and pancreatic dysfunction.

InterestModerate interest

The discussion demonstrates moderate interest by mentioning specific mechanisms like lipid signaling and fatty acid utilization.

EngagementModerate engagement

The responses show some depth by citing mechanisms and associations, but lack extensive analysis or critique.

ImpactModerate impact

The focus on biological pathways suggests recognition of some importance, though the discussion remains at a relatively general level.

Abstract in brief

  • Lipotoxicity refers to the damaging effects of excess fat accumulation on various organs, contributing to insulin resistance and pancreatic beta cell dysfunction, especially in organs like the liver, heart, and muscle.
  • Mechanisms involved include abnormal lipid signaling, mitochondrial dysfunction, and endoplasmic reticulum stress, which impair normal metabolic processes and promote insulin resistance.
  • Increased visceral fat and insulin resistance elevate cardiometabolic risk, with lipotoxicity playing a key role in these interconnected health issues.]

Top posts

Most liked on X and Bluesky
Cankay Koryak
@CankayKoryak · X

Lipotoxicity has roles in insulin resistance and pancreatic disfunction.Increased circulating levels of lipids and the metabolic alterations in fatty acid utilization and intracellular signaling, have been related to insulin resistance in muscle and liver.https://t.co/MzZUYP3V3V.

Jan 11, 2024 · 4,404 followers View post →

All mentions

Cankay Koryak
@CankayKoryak · X

Lipotoxicity has roles in insulin resistance and pancreatic disfunction.Increased circulating levels of lipids and the metabolic alterations in fatty acid utilization and intracellular signaling, have been related to insulin resistance in muscle and liver.https://t.co/MzZUYP3V3V.

Jan 11, 2024 · 4,404 followers View post →
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Dec 25, 2025 View →
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Facebook

... así prevenir esta enfermedad. ✋ DOI 10.1007/978-3-319-48382-5_12 #nutriologanazajur ·

Dec 10, 2024 View →