August 2017 PMID 28605608

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes.

Bruce Neal, Vlado Perkovic, Kenneth W Mahaffey, Dick de Zeeuw, Greg Fulcher, Ngozi Erondu, Wayne Shaw, Gordon Law, Mehul Desai, David R Matthews

Mentions

96
Peak: 24 in Apr 2019
across 9 sources since Jun 2017

Extended reach

429,078
potential audience

Total likes

1,158

Video views

23,858

Mentions per month

Jun 2017 – Dec 2025

Where it's discussed

  • X / Twitter63 posts
  • News18 articles
  • Facebook5 posts
  • Bluesky3 posts
  • YouTube2 videos
  • Blogs2 articles
  • Instagram1 posts
  • LinkedIn1 posts
  • Reddit1 posts

AI synopsis

What people are saying

Overall, the discussions reflect a balanced curiosity and involvement, with examples such as references to study names like CANVAS and CREDENCE, and concerns about safety signals like amputations, which show both analytical interest and cautious engagement. The tone ranges from clinical updates to safety debates, emphasizing the article's relevance in ongoing medical conversations.

AgreementNeither agree nor disagree

The discussions show mixed opinions, with some recognizing the benefits of canagliflozin but also raising safety concerns like amputation risks.

InterestModerate interest

The posts demonstrate moderate curiosity about the study's findings and implications, often referencing specific trials like CANVAS and CREDENCE.

EngagementModerate engagement

Many posts include detailed references to trial results, safety considerations, and ongoing debates, indicating a higher level of engagement.

ImpactModerate impact

The discussions highlight that the article influences clinical considerations and safety debates, suggesting a noteworthy but not transformative impact.

Abstract in brief

  • Canagliflozin, a drug that lowers blood sugar, blood pressure, body weight, and albumin in people with type 2 diabetes, was shown to reduce the risk of serious cardiovascular events like heart attack and stroke in high-risk patients.
  • Although renal benefits were observed, such as slowing kidney disease progression, these were not definitively statistically significant.
  • The treatment was associated with an increased risk of amputation, especially at the toes or feet, which is an important safety consideration.

Top posts

Most liked on X and Bluesky
Edgar V. Lerma
@edgarvlermamd · X

CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWCN

Apr 14, 2019 · 18 likes · 13 shares · 33,994 followers View post →
Int Society of Nephrology
@ISNkidneycare · X

#ISNWebinar: Diabetes and its cardiac outcomes in people with and without kidney disease (CV outcome trials) Further reading: https://t.co/gZYEfZthJV https://t.co/pxg7VuTPmM https://t.co/TkL1bUZAzh https://t.co/jiReouHd2o https://t.co/afT6tGHSqa https://t.co/0aWpT6gJc6 https://t.co/KSEVGqkcZD

Feb 24, 2021 · 13 likes · 7 shares · 29,552 followers View post →
Edgar V. Lerma
@edgarvlermamd · X

CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephpearls #NephJC

Apr 23, 2019 · 12 likes · 8 shares · 33,994 followers View post →
SABOURETCardiologist
@SABOURETCardio · X

#Canagliflozin and Cardiovascular and Renal Events in #T2D Available in France but I’m convinced that most #HCP forgot #CREDENCE and #CANVAS studies … https://t.co/uhrDb9aOiM

Nov 13, 2025 · 12 likes · 2 shares · 31,605 followers View post →
Melissa Bregger, MD, FACP
@MelBreggs · X

1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a brief overview of CANVAS & CREDENCE Trials to review why an SGLT2i was started. CANVAS Trial: https://t.co/mfw2cI9buz CREDENCE Trial: https://t.co/2rGjYf92WQ

Feb 17, 2020 · 12 likes · 4 shares · 1,702 followers View post →
Edgar V. Lerma
@edgarvlermamd · X

Whether the increased risk of lower limb amputation in the CANVAS Program was due to differing trial populations or protocols, or to chance remains unclear #NKFClinicals

May 10, 2019 · 8 likes · 3 shares · 33,994 followers View post →

All mentions

sophia
@sophia8666ac · X

RT @SABOURETCardio: #Canagliflozin and Cardiovascular and Renal Events in #T2D Available in France but I’m convinced that most #HCP forgot…

Nov 25, 2025 · 2 shares · 500 followers View post →
Juan Carlos Obaya
@jcobaya69 · X

RT @SABOURETCardio: #Canagliflozin and Cardiovascular and Renal Events in #T2D Available in France but I’m convinced that most #HCP forgot…

Nov 13, 2025 · 2 shares · 858 followers View post →
SABOURETCardiologist
@SABOURETCardio · X

#Canagliflozin and Cardiovascular and Renal Events in #T2D Available in France but I’m convinced that most #HCP forgot #CREDENCE and #CANVAS studies … https://t.co/uhrDb9aOiM

Nov 13, 2025 · 12 likes · 2 shares · 31,605 followers View post →
まいち
@maiti_86 · X

@kksft @KobaKobauro @muscle_penguin_ SGLT2iは心臓病の患者に対してポジティブな効果があります。 SGLT2iはグルコースを尿から排出することでインスリンを下げケトン体を増やす作用があります。 腎臓疾患にも効果があります。 https://t.co/Jh5XhfMR7N https://t.co/nz6ZXSXZUz

Apr 21, 2024 · 2 likes · 11,070 followers View post →
ゆかこ☺︎
@yukaco_ph · X

#ゆかこメモ

Oct 22, 2023 · 8 likes · 869 followers View post →
Joel M. Topf, MD FACP
@kidney_boy · X

@Tacothenation1 No specific threshold. In CANVAS they had to have an A1c <10.5 https://t.co/3hXZUMARLB

Dec 8, 2022 · 2 likes · 63,835 followers View post →
Gregorio Romero-González
@Tubulocentric · X

@kidney_boy https://t.co/Dw1oq3Pjo6

Sep 25, 2022 · 2 likes · 3,007 followers View post →
cardio-met
@cardiomet_CE · X

24b) Other #DPP4i, #basal #insulin, and α-GI are neutral but and @GLP1 RAs have modest benefit from meta-analysis. #SGLT2i show consistent and robust benefits. Consider

May 11, 2022 · 3 likes · 4,210 followers View post →
NG20194
@NG20194 · X

@abledoc Why it would be increasing risk for amputation? Canagliflozin lowers risk of CVD, but increases risk of amputation https://t.co/f2DFRV7wbK

Jun 14, 2021 · 179 followers View post →
Yasser UMKCRCT
@ymhs92 · X

CANVAS: Among patients with T2D and high CV risk, canagliflozin was associated with lower CV and renal events but higher risk of amputation #UMKCRCT https://t.co/SxOGWqDwtj

Mar 20, 2021 · 9 followers View post →
EURORECKD
@euroreckd · X

RT @ISNkidneycare: #ISNWebinar: Diabetes and its cardiac outcomes in people with and without kidney disease (CV outcome trials) Further rea…

Feb 24, 2021 · 7 shares · 174 followers View post →
Dr. Carlos Orantes
@nefrorantes · X

RT @ISNkidneycare: #ISNWebinar: Diabetes and its cardiac outcomes in people with and without kidney disease (CV outcome trials) Further rea…

Feb 24, 2021 · 7 shares · 5,000 followers View post →
Rayhan
@Nephwizard · X

RT @ISNkidneycare: #ISNWebinar: Diabetes and its cardiac outcomes in people with and without kidney disease (CV outcome trials) Further rea…

Feb 24, 2021 · 7 shares · 170 followers View post →
Angel Cesar Ortiz
@AngelCesarOrtiz · X

RT @ISNkidneycare: #ISNWebinar: Diabetes and its cardiac outcomes in people with and without kidney disease (CV outcome trials) Further rea…

Feb 24, 2021 · 7 shares · 1,004 followers View post →
carmen torres
@tatatorres1515 · X

RT @ISNkidneycare: #ISNWebinar: Diabetes and its cardiac outcomes in people with and without kidney disease (CV outcome trials) Further rea…

Feb 24, 2021 · 7 shares · 606 followers View post →
Fundación Renal Española
@FundacionRenalE · X

RT @ISNkidneycare: #ISNWebinar: Diabetes and its cardiac outcomes in people with and without kidney disease (CV outcome trials) Further rea…

Feb 24, 2021 · 7 shares · 3,941 followers View post →
Int Society of Nephrology
@ISNkidneycare · X

#ISNWebinar: Diabetes and its cardiac outcomes in people with and without kidney disease (CV outcome trials) Further reading: https://t.co/gZYEfZthJV https://t.co/pxg7VuTPmM https://t.co/TkL1bUZAzh https://t.co/jiReouHd2o https://t.co/afT6tGHSqa https://t.co/0aWpT6gJc6 https://t.co/KSEVGqkcZD

Feb 24, 2021 · 13 likes · 7 shares · 29,552 followers View post →
Juan Senior
@jsenior64 · X

https://t.co/PraSDuCNkG

Jan 11, 2021 · 1 like · 11,090 followers View post →
パフェ
@rosye_shukuru · X

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes - PubMed https://t.co/JaZyj6KP3q

May 7, 2020 · 64 followers View post →
たけちゃん
@nitrotake · X

そういえば、読んだことなかった https://t.co/kuIn6pbC62

May 3, 2020 · 1 like · 1,440 followers View post →
Letaief
@hmidato · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephm…

Mar 13, 2020 · 3 shares · 368 followers View post →
RXKEVING
@KNRXRX · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephm…

Mar 13, 2020 · 3 shares · 354 followers View post →
Nouf Al Marshdi
@Noufmarshdi · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephm…

Mar 13, 2020 · 3 shares · 8,211 followers View post →
Edgar V. Lerma
@edgarvlermamd · X

CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephmadness 2️⃣

Mar 13, 2020 · 3 likes · 3 shares · 33,994 followers View post →
Doctor
@abmdoctor · X

RT @MelBreggs: 1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a bri…

Feb 21, 2020 · 4 shares · 649 followers View post →
Leesa Novotny
@DocLeesa · X

RT @MelBreggs: 1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a bri…

Feb 17, 2020 · 4 shares · 33 followers View post →
Colin Gallagher
@clngallagher · X

RT @MelBreggs: 1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a bri…

Feb 17, 2020 · 4 shares · 72 followers View post →
Michelle Fleshner
@MFleshner301 · X

RT @MelBreggs: 1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a bri…

Feb 17, 2020 · 4 shares · 522 followers View post →
Melissa Bregger, MD, FACP
@MelBreggs · X

1/3-Day 8: Cardiology started an SGLT2 inhibitor on a patient for the first time. Thought it would be good to give a brief overview of CANVAS & CREDENCE Trials to review why an SGLT2i was started. CANVAS Trial: https://t.co/mfw2cI9buz CREDENCE Trial: https://t.co/2rGjYf92WQ

Feb 17, 2020 · 12 likes · 4 shares · 1,702 followers View post →
Firstclassessaywriters
@EssaysClass · X

[Solution]Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes https://t.co/lM78LDCx4J

Oct 18, 2019 · 94 followers View post →
Dr. Carlos Orellana
@orellanamd · X

RT @edgarvlermamd: Whether the increased risk of lower limb amputation in the CANVAS Program was due to differing trial populations or prot…

Sep 13, 2019 · 3 shares · 549 followers View post →
Edgar V. Lerma
@edgarvlermamd · X

@Joe_Vassalotti CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephpearls

Jul 2, 2019 · 33,994 followers View post →
Waqar Ayub
@waqar_ayub · X

RT @NEJM: Original Article: Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes (CANVAS) https://t.co/aEGa1ggSpw #ADA2017

May 27, 2019 · 94 shares · 49 followers View post →
Cardiac Surgery Congress
@CongressCardiac · X

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes To know more : https://t.co/rtMD0TxgHr #cardiologyconference #cardiologymeeting #cardiologistsconference #cardiovascular #cardiacdisease #cardiacmuscle https://t.co/rmPUPgtzf0

May 18, 2019 · 155 followers View post →
maría marques vidas
@mmvidas · X

RT @edgarvlermamd: Whether the increased risk of lower limb amputation in the CANVAS Program was due to differing trial populations or prot…

May 11, 2019 · 3 shares · 2,361 followers View post →
veronica coro
@veronicacoro1 · X

RT @edgarvlermamd: Whether the increased risk of lower limb amputation in the CANVAS Program was due to differing trial populations or prot…

May 10, 2019 · 3 shares · 109 followers View post →
Edgar V. Lerma
@edgarvlermamd · X

Whether the increased risk of lower limb amputation in the CANVAS Program was due to differing trial populations or protocols, or to chance remains unclear #NKFClinicals

May 10, 2019 · 8 likes · 3 shares · 33,994 followers View post →
Sara Asecas
@SaraKeru · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephp…

Apr 27, 2019 · 8 shares · 155 followers View post →
Ana Maria Matias
@AMCMA6 · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephp…

Apr 25, 2019 · 8 shares · 314 followers View post →
Roberto Gutiérrez
@DrRobertoGuti · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephp…

Apr 24, 2019 · 8 shares · 783 followers View post →
clara lopez
@claraelvia · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephp…

Apr 23, 2019 · 8 shares · 244 followers View post →
Ernesto LopezAlmaraz
@kidney_doctor · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephp…

Apr 23, 2019 · 8 shares · 5,162 followers View post →
Franklin Loachamin
@FranLoachamin · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephp…

Apr 23, 2019 · 8 shares · 4,891 followers View post →
Rodrigo Nunes Cal
@CalZole · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephp…

Apr 23, 2019 · 8 shares · 3,313 followers View post →
Arshad Ali
@aldorenin · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephp…

Apr 23, 2019 · 8 shares · 592 followers View post →
Edgar V. Lerma
@edgarvlermamd · X

CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #Nephpearls #NephJC

Apr 23, 2019 · 12 likes · 8 shares · 33,994 followers View post →
Sourabh Sharma
@iamnephrologist · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 21, 2019 · 13 shares · 4,016 followers View post →
Priya John
@drpriyajohn · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 21, 2019 · 13 shares · 2,177 followers View post →
Reny Duarsa
@Renaladdict · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 21, 2019 · 13 shares · 503 followers View post →
Mostapha Habib Allah
@NephroMostapha · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 21, 2019 · 13 shares · 1,538 followers View post →
Sarah Finer
@Sarah_Finer · X

@kidneydoc101 @DrGavinDreyer @toates_19 @OK_Kidney @Ashidotic Likely significantly underpowered. The excess risk of amputation w Canagliflozin was in the combined CANVAS trials, n=10,000 https://t.co/4HtuaLYrip

Apr 15, 2019 · 1,319 followers View post →
Basu Gopal
@BasuNephro · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 14, 2019 · 13 shares · 2,969 followers View post →
Luis Enrique Alvarez
@LuisAlvarezRa · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 14, 2019 · 13 shares · 912 followers View post →
Mana
@manasigh · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 14, 2019 · 13 shares · 329 followers View post →
Roberto Gutiérrez
@DrRobertoGuti · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 14, 2019 · 13 shares · 783 followers View post →
Anace Pastor ✨️ Renalis
@anace710 · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 14, 2019 · 13 shares · 1,899 followers View post →
Franklin Loachamin
@FranLoachamin · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 14, 2019 · 13 shares · 4,891 followers View post →
salman hussain
@salmanjamia · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 14, 2019 · 13 shares · 62 followers View post →
Tired & Sakit
@tulunsokit · X

RT @edgarvlermamd: CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWC…

Apr 14, 2019 · 13 shares · 3,703 followers View post →
Edgar V. Lerma
@edgarvlermamd · X

CANVAS: Canagliflozin and CV & Renal events in Type 2 Diabetes ca. 2017 from @NEJM #VisualAbstract by @kidney_boy #ISNWCN

Apr 14, 2019 · 18 likes · 13 shares · 33,994 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes —cited by Dr. Joel Topf, MD, FACP, St. Clair University @kidney_boy #KidneyCon “There was an amputation signal... we’ll talk more about that later.” https://t.co/rkEebrP0h8

Apr 13, 2019 · 3,314 followers View post →
David A. Cohen
@DavidACohen_MD · X

15/15 Links to citations: https://t.co/MVMmAtpIaf https://t.co/PY4Dn6X9Bn https://t.co/VX44qck2n2 https://t.co/s2GQbKKI3R https://t.co/meSES5A9HF https://t.co/Poio86DZ74 https://t.co/aneU63NacY

Mar 3, 2019 · 3 likes · 2,512 followers View post →
Paola Beltran Tronco
@paolabel_cardio · X

RT @CristobMorales: @ValleAlfonso @secardiologia @almucastro01 @jlgorriz @vic_pallares @rafavidalperez @mendez_bailon @paolabel_cardio @cri…

Feb 18, 2019 · 11 shares · 3,289 followers View post →
Hofstra Kidney
@hofstrakidney.bsky.social · Bluesky

http://www.nejm.org/doi/full/10.1056/NEJMoa1611925

Jun 19, 2017 View post →
Joel Topf
@kidneyboy.bsky.social · Bluesky

#CANVAS looks like a smaller effect size than Emma-ref but overall delighted to see a second outcome trial that's + http://www.nejm.org/doi/full/10.1056/NEJMoa1611925

Jun 12, 2017 View post →
Joel Topf
@kidneyboy.bsky.social · Bluesky

40% reduction in GFR, that's a new one. Anyone know where that came from? #CANVAS http://www.nejm.org/doi/full/10.1056/NEJMoa1611925

Jun 12, 2017 View post →
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รีวิวยาในกลุ่ม SGLT-2 inhibitor 3/8/63 ------------------------- สวัสดีทุกคน วัน ...
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... 10.1056/nejmoa1504720 DECLARE TIMI https://www.nejm.org/doi ... org/doi/full/10.1056/NEJMoa1611925 DAPA-HF https://www.nejm. org/doi ...

Aug 3, 2020 View →
James “Jimmy” Hotz, MD FACP November 22, 2019
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... 10.1056/NEJMoa1811744 #5 Canagliflozin-Renal-CREDENCE https://www.nejm.org/doi/full/10.1056/NEJMoa1611925 #6 Canagliflozin-CAD-Canvas https ...

Nov 22, 2019 View →
At last, a new treatment option for diabetes-related chronic kidney ...
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doi: 10.1056/NEJMoa1611925. Wiviott SD, Raz I, Bonaca MP et al. New Engl J Med 2019;380:347–357. doi: 10.1056/NEJMoa1812389.

Sep 20, 2019 View →
SGLT inhibitors present promising step for type 1 diabetes
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2017;doi:10.1056/ NEJMoa1611925. Rosenstock J, et al. Diabetes Care. 2018;doi:10.2337/dc18-1749. Wiviott SD, et al. N Engl J Med. 2019;doi ...

Jun 20, 2019 View →
After FDA Panel Vote, Some See Next Generation of Cardiovascular ...
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doi: 10.1056/NEJMoa1611925. 7. Zinman B, Wanner C, Lachin JM, et al; EMPA-REG OUTCOME Investigators. Empagliflozin, cardiovascular outcomes ...

Dec 27, 2018 View →
New data from landmark CVD-REAL study of patients with type-2 ...
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DOI: 10.1056/NEJMoa1611925. 9. Kosiborod M, et al. Lower risk of heart failure and death in patients initiated on SGLT-2 inhibitors versus ...

Mar 12, 2018 View →
Can Canaglifozin Communicate Consistency with CANVAS ...
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... 10.1056/NEJMoa1611925. [Epub ahead of print]. Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes. Neal B, Perkovic V ...

Jun 19, 2017 View →
Invokana : r/pharmacy
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This recommendation is coming based off of the [CANVAS-R Trial] (http://www.nejm.org/doi/full/10.1056/NEJMoa1611925#t=article) findings that ...

Jun 17, 2017 View →
Major study heralds new era in treatment of type 2 diabetes ...
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New England Journal of Medicine, 2017; DOI: 10.1056/NEJMoa1611925. Cite This Page: MLA; APA; Chicago. George Institute for Global Health. "Major ...

Jun 15, 2017 View →
CANVAS Finds Lower Risk of CV Events for Invokana | AJMC
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DOI: 10.1056/NEJMoa1611925. Newsletter. Stay ahead of policy, cost, and value—subscribe to AJMC for expert insights at the intersection of ...

Jun 12, 2017 View →