Cochrane Database Syst Rev June 2017 PMID 28616955

Niacin for primary and secondary prevention of cardiovascular events.

Stefan Schandelmaier, Matthias Briel, Ramon Saccilotto, Kelechi K Olu, Armon Arpagaus, Lars G Hemkens, Alain J Nordmann

Mentions

80
Peak: 17 in Apr 2022
across 6 sources since Apr 2019

Extended reach

1,191,419
potential audience

Total likes

17,358

Video views

903,332

Mentions per month

Apr 2019 – May 2024

Where it's discussed

  • News39 articles
  • X / Twitter25 posts
  • Facebook9 posts
  • Blogs3 articles
  • YouTube2 videos
  • Reddit2 posts

AI synopsis

What people are saying

The group's tone leans toward skepticism, with many posts strongly advising against niacin use, citing dangers or lack of effectiveness, such as 'Avoid niacin' and 'Changes in cholesterol markers don’t necessarily influence heart disease risk.' The language used is direct and dismissive, reflecting widespread doubts about niacin's benefits and emphasizing its potential harm, which explains the overall negative scores.

AgreementLow agreement

Most discussions question or dismiss the benefits of niacin, with many highlighting that evidence for its effectiveness is contested or debunked.

InterestModerate interest

The overall curiosity appears moderate, with some posts pondering the medication’s role, but many show little enthusiasm or curiosity about new findings.

EngagementLow engagement

Interactions are surface-level, often dismissing niacin with phrases like 'avoid niacin' and sharing brief opinions without deep analysis.

ImpactLow impact

The discussions seem to reinforce existing skepticism or negative perceptions about niacin rather than new or transformative insights, indicating limited perceived real-world impact.

Abstract in brief

  • The text reviews a study that evaluates whether niacin (nicotinic acid) can effectively prevent cardiovascular events by lowering bad cholesterol (LDL) and triglycerides and raising good cholesterol (HDL), but the evidence remains controversial.
  • Researchers analyzed 23 randomized controlled trials involving nearly 40,000 participants to compare niacin alone or added to statins against placebo or other therapies, focusing on outcomes like mortality, cardiovascular events, and side effects.
  • The findings, based on detailed meta-analyses and bias assessments, aim to determine if niacin offers significant health benefits or drawbacks, considering factors like treatment duration and existing heart disease or statin use.]

Top posts

Most liked on X and Bluesky
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

@KnowledgeAcqui1 @flutteringstraw Niacin for primary and secondary prevention of cardiovascular events https://t.co/DAGf8gdeZx More recent paper debunking that theory. Changes in cholesterol markers don’t necessarily influence heart disease risk. https://t.co/wNc91EF9el

Feb 20, 2024 · 11 likes · 2 shares · 133,606 followers View post →
Reiner 
@erlesen · X

Nicotinic acid (Niacin) is known to decrease LDL‐cholesterol, and triglycerides, and increase HDL‐cholesterol levels. The evidence of benefits with niacin monotherapy is controversial https://t.co/qLVSFWuxWr Niacin (B3) senkt LDL + Triglyceride, erhöht HDL https://t.co/CC5Wzt6zBZ

Apr 21, 2019 · 1 like · 7,862 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@floraoddchild @HerbsandDirt @deNutrients https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 1 like · 647 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

RT @Grimhood: @KnowledgeAcqui1 @flutteringstraw Niacin for primary and secondary prevention of cardiovascular events https://t.co/DAGf8gdeZ…

Feb 20, 2024 · 2 shares · 133,606 followers View post →
にいやん
@niiyan51 · X

Niacin for primary and secondary prevention of cardiovascular events. - PubMed - NCBI https://t.co/dLpI9yA81U

Jul 15, 2019 · 1,077 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@dmitry_kats Can increase risk if stroke https://t.co/i86tPG741M

Apr 17, 2022 · 647 followers View post →

All mentions

ManekiPink
@ManekiPink · X

RT @Grimhood: @KnowledgeAcqui1 @flutteringstraw Niacin for primary and secondary prevention of cardiovascular events https://t.co/DAGf8gdeZ…

Feb 20, 2024 · 2 shares · 90 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

RT @Grimhood: @KnowledgeAcqui1 @flutteringstraw Niacin for primary and secondary prevention of cardiovascular events https://t.co/DAGf8gdeZ…

Feb 20, 2024 · 2 shares · 133,606 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

@KnowledgeAcqui1 @flutteringstraw Niacin for primary and secondary prevention of cardiovascular events https://t.co/DAGf8gdeZx More recent paper debunking that theory. Changes in cholesterol markers don’t necessarily influence heart disease risk. https://t.co/wNc91EF9el

Feb 20, 2024 · 11 likes · 2 shares · 133,606 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@Enheduannaofur @BlueSlots @dmitry_kats https://t.co/wrWbwxGz5B https://t.co/i86tPGpdfU

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@Marshafactor1 @jessimiller4888 @dmitry_kats https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@GreenSmoke1776 @anywayshare @dmitry_kats https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@HumanitarianPot @B_Holmer https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@floraoddchild @HerbsandDirt @deNutrients https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 1 like · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@albioniron @glitchedpretext https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@BobSlater18 https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@Jackief42642119 @dmitry_kats https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@ClausDB1 @dmitry_kats https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@chefwanda5 @DeborahtheBruc1 @elkatoon_wayson @DaniiiiV https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@MaddMiche @rebeccasowell8 @MrsA444134 https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@NinjaKimC @LauraWanek @AlyceHager https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@deNutrients https://t.co/wrWbwxG1g3 https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@HumanitarianPot @dmitry_kats Avoid niacin. Dangerous to health. https://t.co/i86tPGoFqm

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@dmitry_kats Can increase risk if stroke https://t.co/i86tPG741M

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@DCGreenZone Not good. Avoid niacin https://t.co/i86tPG741M

Apr 17, 2022 · 647 followers View post →
Ultimate Wildcat NBA NFL MLB FAN account
@budspook · X

@Aquamariah1 @dkdk459 @RenovaAlejandro https://t.co/i86tPGoFqm Avoid niacin

Apr 17, 2022 · 647 followers View post →
Chill Guy
@usha25_2005 · X

@zaidkdahhaj @Grimhood https://t.co/x6JTHylX54

Jan 24, 2022 · 88 followers View post →
DwindleProof
@DwindleProof · X

@FriedScones @JamborOliver It does modulate lipids so it was used for a period of time, but a graph of usage would show a sharp decline about a decade ago when I was in medical school and it was learned that those modulations made no differences to the overall cardiovascular goals. https://t.co/VbkZSxzfKh

Oct 8, 2021 · 321 followers View post →
mystery_nunya
@mystery_nunya · X

@NIHNews @WhiteHouse Yawn. https://t.co/1xihZ8QHBs

Apr 23, 2021 · 427 followers View post →
にいやん
@niiyan51 · X

Niacin for primary and secondary prevention of cardiovascular events. - PubMed - NCBI https://t.co/dLpI9yA81U

Jul 15, 2019 · 1,077 followers View post →
Reiner 
@erlesen · X

Nicotinic acid (Niacin) is known to decrease LDL‐cholesterol, and triglycerides, and increase HDL‐cholesterol levels. The evidence of benefits with niacin monotherapy is controversial https://t.co/qLVSFWuxWr Niacin (B3) senkt LDL + Triglyceride, erhöht HDL https://t.co/CC5Wzt6zBZ

Apr 21, 2019 · 1 like · 7,862 followers View post →