Synopsis of Social media discussions
The discussions reflect strong interest and moderate agreement with the publication, with participants referencing it as a valuable tool for understanding neurodevelopmental disorders and immune responses, often describing the research as 'relevant' and 'informative'. The tone and language suggest a recognition of the study's importance without overly enthusiastic praise, focusing instead on its potential implications.
Agreement
Moderate agreementMost discussions acknowledge the relevance of the study, especially noting its potential to inform understanding of microglial development and neurological disorders.
Interest
High level of interestThe topic of microglial maturation and immune reactivity sparks high interest, particularly among those in neuroscience and medical research communities.
Engagement
Moderate level of engagementParticipants engage by referencing related studies and emphasizing the importance of the methodology and findings, such as the mention of the developmental index.
Impact
Moderate level of impactAlthough the discussions recognize the significance for future research and clinical implications, the overall perceived immediate impact remains moderate.
Social Mentions
YouTube
1 Videos
5 Posts
1 Posts
Metrics
Video Views
1,142
Total Likes
8
Extended Reach
2,051
Social Features
7
Timeline: Posts about article
Top Social Media Posts
Eleftheria (Ria) Kodosaki
@NeuroSGS @ChristoBrighton https://t.co/m7fZTldHG7 here's a review with some relevant references, and here's a research article for both rodents and humans: https://t.co/LAPVpn8Bi2
view full post
Posts referencing the article
Sex Differences in Microglial Development and Immune Reactivity Analysis
This study developed a microglial developmental index based on gene expression profiles, revealing delays in male microglial maturation and the impact of immune activation. Accelerated development is linked to neurological disorders like Alzheimer's and autism.
June 28, 2017
1,142 views
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@NeuroSGS @ChristoBrighton https://t.co/m7fZTldHG7 here's a review with some relevant references, and here's a research article for both rodents and humans: https://t.co/LAPVpn8Bi2
view full postDecember 14, 2023
Abstract Synopsis
- This study developed a microglial developmental index (MDI) based on gene expression profiles from purified microglia in mice, which showed that microglial development is delayed in males compared to females and can be accelerated by immune activation.
- Applying the MDI to human brain data revealed that accelerated microglial development is associated with neurological disorders like Alzheimer's disease and autism, suggesting microglial maturation influences disease pathology.
- The research highlights the importance of understanding microglial development, with the MDI serving as a versatile tool to investigate how microglia contribute to brain health, disease, and responses to factors like stress or treatment.]
Eleftheria (Ria) Kodosaki
@micro_glia (Twitter)