BMC Biol July 2017 PMID 28705195

Peto's Paradox: how has evolution solved the problem of cancer prevention?

Marc Tollis, Amy M Boddy, Carlo C Maley

Mentions

103
Peak: 4 in Aug 2019
across 6 sources since Dec 2017

Extended reach

856,835
potential audience

Total likes

15,652

Video views

755,421

Mentions per month

Dec 2017 – Dec 2024

Where it's discussed

  • News45 articles
  • X / Twitter29 posts
  • Blogs11 articles
  • YouTube8 videos
  • Facebook8 posts
  • Reddit2 posts

AI synopsis

What people are saying

The discussions highlight widespread curiosity and recognition of the topic's importance, with expressions such as 'why do whales rarely get cancer?' and mentions of the gene TP53. Words like 'interesting' and questions about dinosaur cancer reveal a tone of inquiry and fascination, which indicates that the publication stimulates engagement and has potential impact by prompting further exploration of natural cancer defenses across species.

AgreementModerate agreement

Most discussions recognize the significance of Peto's Paradox and acknowledge the role of evolutionary mechanisms in addressing cancer prevention, indicating a general consensus with the publication's premise.

InterestHigh interest

Posts reflect curiosity about why large mammals like whales have low cancer rates, showing genuine interest in evolutionary biology and its implications for cancer research.

EngagementModerate engagement

Several participants reference specific mechanisms like the TP53 gene and note that the topic prompts them to look deeper into topics like dinosaur cancer or comparative cancer incidence across species.

ImpactModerate impact

The debates and references suggest that this publication sparks meaningful conversations about evolutionary strategies and could influence ongoing research and understanding in oncology and evolutionary biology.

Abstract in brief

  • Petos Paradox addresses the question of why large, long-lived animals (like elephants and whales) do not have higher rates of cancer than smaller animals, despite having many more cells and longer lifespans, which should theoretically increase cancer risk.
  • Evolution appears to have developed enhanced cancer suppression mechanisms in these large animals multiple times, effectively protecting them from cancer despite their size and age.
  • The text explores current understanding of Petos Paradox and highlights areas where further research is needed to uncover how evolution has solved this cancer prevention puzzle.]

Top posts

Most liked on X and Bluesky
Prof. Nikolai Slavov
@slavov_n · X

@Xirong7 @arjunrajlab That is a very interesting one https://t.co/C479cxJXo6 I do not know much about Peto's paradox and the reliability of the estimated incidence of cancer in whales, but it's interesting!

Jan 10, 2021 · 14 likes · 20,175 followers View post →
BMC Biology
@BMCBiology · X

In case you missed it: Peto’s Paradox: how has #evolution solved the problem of #cancer prevention? https://t.co/SiUqIZRAMr https://t.co/jLNfKAlcII

Aug 9, 2019 · 8 likes · 3 shares · 9,009 followers View post →
Kimberly Luddy
@luddyka · X

Peto’s Paradox: how has evolution solved the problem of cancer prevention? @ClionaOfarrelly https://t.co/tEAOUGahYq https://t.co/UJXDXG6d6f

Apr 13, 2021 · 8 likes · 2 shares · 1,465 followers View post →
Abhinaba Das
@Abhinaba_Das_ · X

https://t.co/uemIW82aTA

Dec 26, 2022 · 5 likes · 63 followers View post →
Amy Boddy
@amy_boddy · X

@duffy_ma Also, will shamelessly plug this paper we wrote on Peto's paradox, it seems to be a fav topic among my undergrads in evmed: https://t.co/DQscLb4URT

Aug 19, 2019 · 4 likes · 1 share · 1,315 followers View post →
Todd Scarbrough
@toddscarbrough · X

@VedangMurthy @Sushilberiwal Counter-intuitive And somewhat akin to Peto's Paradox https://t.co/JyCKTzPvn9 https://t.co/UyQ8zud5Fb

Jul 29, 2022 · 3 likes · 3,389 followers View post →

All mentions

nadie
@Sunlightwatcher · X

El kirchnerismo fue el super-cáncer del cáncer que es el peronismo. https://t.co/qlsqdbChm3

Dec 22, 2024 · 23 followers View post →
alfred fischer
@alfredfischer17 · X

Eigentlich müssten größere Säugetiere häufiger Krebs haben, aber das stimmt nicht. … sog. Peto‘s paradox. Wahrscheinlich spielt das Tumorsuppressorgen TP53 eine entscheidende Rolle. #evolution #onkologie #inzidenz #cancer https://t.co/B0uyOeteTi

May 16, 2024 · 3 likes · 361 followers View post →
Cary Woodruff
@DoubleBeam · X

@DavidQuammen A bit of a science interest crossroads, but while it's quite debated - and needs a lot more examination - Peto's Paradox has even been hypothesized in dinosaurs (Tollis et al 2017; Woodruff et al 2018). https://t.co/CmHaI1HUGS https://t.co/g6fP8xbtt9

Apr 17, 2024 · 3,577 followers View post →
Recognized female by federal and state government
@PurpleWOrange · X

Why do whales rarely get cancer? https://t.co/kIONEfbD1M

May 27, 2023 · 2,219 followers View post →
Xmax2020
@EXsouthBay · X

How The Evolution Of Blue Whales Could Help Beat Cancer https://t.co/bHtht8Aw6e via @YouTube

May 25, 2023 · 178 followers View post →
Abhinaba Das
@Abhinaba_Das_ · X

https://t.co/uemIW82aTA

Dec 26, 2022 · 5 likes · 63 followers View post →
Vini
@Oviniiilll · X

@DiggyDigsIt @WeiseFranklin @gunsnrosesgirl3 Ever heard of Peto’s Paradox? https://t.co/LOpST838pL And you gotta consider that cancer incidence falls drastically among Phyla. The Arthropoda phylum, as it is far older than our own, it's almost oblivious to cancer - ofc, evolution did have a lot of time to work on them.

Oct 28, 2022 · 1 like · 403 followers View post →
Antony Stanley
@antonystanley09 · X

Since many lineages faced the trade-off between large body size and cancer risk during their evolution, there have likely been many different pathways in which cancer suppression has evolved. https://t.co/8K6xNpDyfX

Sep 12, 2022 · 2 likes · 2,307 followers View post →
Todd Scarbrough
@toddscarbrough · X

@VedangMurthy @Sushilberiwal Counter-intuitive And somewhat akin to Peto's Paradox https://t.co/JyCKTzPvn9 https://t.co/UyQ8zud5Fb

Jul 29, 2022 · 3 likes · 3,389 followers View post →
Panos Kotsikis
@pKotsikis · X

July 2022, msac149, https://t.co/cpKUJGfxHj 2. Tollis, M., Boddy, A.M. & Maley, C.C. Peto’s Paradox: how has evolution solved the problem of cancer prevention?. BMC Biol 15, 60 (2017). https://t.co/lBmExU2dv2 3.Abegglen LM, Caulin AF, Chan A, et al. Potential Mechanisms for

Jul 19, 2022 · 3 likes · 793 followers View post →
BMC Biology
@BMCBiology · X

What is Peto’s paradox? Why should I care? And did dinosaurs get cancer? See this Q&A from our ‘In the Light of Evolution’ series for a primer https://t.co/00CYcZoozA

Sep 15, 2021 · 9,009 followers View post →
Ana Teles
@Anabteles · X

RT @luddyka: Peto’s Paradox: how has evolution solved the problem of cancer prevention? @ClionaOfarrelly https://t.co/tEAOUGahYq https://t…

Apr 13, 2021 · 2 shares · 436 followers View post →
Kimberly Luddy
@luddyka · X

Peto’s Paradox: how has evolution solved the problem of cancer prevention? @ClionaOfarrelly https://t.co/tEAOUGahYq https://t.co/UJXDXG6d6f

Apr 13, 2021 · 8 likes · 2 shares · 1,465 followers View post →
Alka Gupta
@alka_gupta__ · X

Few things that keep you hooked on to science! thanks @perry30011994 for discussing such amazing things!! https://t.co/OhOF4DCdsO

Mar 2, 2021 · 1 like · 399 followers View post →
Gabi Ficz
@GabriellaFicz · X

For those interested in Peto's paradox, which assumes that "....the risk of developing cancer should be a function of the number of cell divisions in an organism’s lifetime". https://t.co/NHSQdDaydw

Jan 10, 2021 · 2 likes · 954 followers View post →
Prof. Nikolai Slavov
@slavov_n · X

@Xirong7 @arjunrajlab That is a very interesting one https://t.co/C479cxJXo6 I do not know much about Peto's paradox and the reliability of the estimated incidence of cancer in whales, but it's interesting!

Jan 10, 2021 · 14 likes · 20,175 followers View post →
Dr Subroto Roy
@subyroy · X

Peto’s Paradox... https://t.co/Pk3UfIUKup https://t.co/ibPh2Su3C2

Nov 25, 2020 · 6,667 followers View post →
Prof Mary J. O'Connell
@Evol_Molly · X

RT @BMCBiology: In case you missed it: Peto’s Paradox: how has #evolution solved the problem of #cancer prevention? https://t.co/SiUqIZRAMr…

Oct 26, 2020 · 3 shares · 1,842 followers View post →
James Boyle, PhD
@JBoyle_Paleo · X

RT @BMCBiology: In case you missed it: Peto’s Paradox: how has #evolution solved the problem of #cancer prevention? https://t.co/SiUqIZRAMr…

Oct 25, 2020 · 3 shares · 320 followers View post →
Himender Bharti
@adubharti · X

Peto’s Paradox: how has evolution solved the problem of cancer prevention? | BMC Biology | Full Text https://t.co/kA5rcvnqRY

Oct 25, 2020 · 1,325 followers View post →
Antonio Rodríguez D.
@antonio_r_d · X

RT @ExoPlanetascom: Vídeo MEDICINA: ¿Un TUMOR puede tener un TUMOR?

May 23, 2020 · 1 share · 5,114 followers View post →
EXOPLANETAS Noticias de Ciencia y Tecnología
@ExoPlanetascom · X

Vídeo MEDICINA: ¿Un TUMOR puede tener un TUMOR?

May 16, 2020 · 2 likes · 1 share · 16,626 followers View post →
Aysenur
@onraysenr · X

https://t.co/ktKcjLmYLs paradox hakkında daha fazla bilgi almak için iyi bir makale.

Mar 5, 2020 · 257 followers View post →
Stephen Riffle, Ph.D.
@EyaSpectre · X

@marielmohns https://t.co/0xiLXZEcOd

Nov 6, 2019 · 1 like · 1,208 followers View post →
Meghan Duffy
@duffy_ma · X

RT @amy_boddy: @duffy_ma Also, will shamelessly plug this paper we wrote on Peto's paradox, it seems to be a fav topic among my undergrads…

Aug 19, 2019 · 1 share · 9,280 followers View post →
Amy Boddy
@amy_boddy · X

@duffy_ma Also, will shamelessly plug this paper we wrote on Peto's paradox, it seems to be a fav topic among my undergrads in evmed: https://t.co/DQscLb4URT

Aug 19, 2019 · 4 likes · 1 share · 1,315 followers View post →
Gene Jockey
@gene_jockey · X

RT @BMCBiology: In case you missed it: Peto’s Paradox: how has #evolution solved the problem of #cancer prevention? https://t.co/SiUqIZRAMr…

Aug 12, 2019 · 3 shares · 161 followers View post →
BMC Biology
@BMCBiology · X

In case you missed it: Peto’s Paradox: how has #evolution solved the problem of #cancer prevention? https://t.co/SiUqIZRAMr https://t.co/jLNfKAlcII

Aug 9, 2019 · 8 likes · 3 shares · 9,009 followers View post →
Jon Humphries
@JDHL18 · X

Peto’s Paradox: how has evolution solved the problem of cancer prevention? https://t.co/ToKHmcmCQ1

Jul 1, 2019 · 2,502 followers View post →