Journal Reference: "It takes two to tango: NAD+ and sirtuins in aging/longevity control" Authors: Shin-Ichiro Imai, PhD, Leonard Guarente, PhD Afilliations: @WUSTLmed , @kochinstitute , @MIT Source Publication: @nature
It takes two to tango: NAD and sirtuins in aging/longevity control.
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Jul 2019 – Jun 2025Where it's discussed
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Facebook12 posts
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YouTube7 videos
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What people are saying
The discussions demonstrate a strong recognition of the research's importance, with comments like 'slowing aging by design' and mentions of NAD supplements, emphasizing their potential impact. The tone varies from supportive enthusiasm to curiosity, highlighting both understanding of the scientific content and interest in its applications.
Most discussions acknowledge the importance of the NAD-sirtuin connection in aging, reflecting general agreement on the article's significance.
The high interest score indicates that people are actively engaging with the topic, likely due to the relevance of aging research and potential therapies.
Posts show moderate engagement, with some referencing scientific terms and implications, but few delve deeply into mechanisms or critique.
Participants seem to believe the research could influence future studies or treatments, although it's still in the research phase.
Abstract in brief
- The article explains how NAD (nicotinamide adenine dinucleotide) and sirtuins are closely linked in regulating aging and longevity, with this relationship being evolutionarily conserved across many organisms.
- As humans age, NAD levels decrease, which reduces sirtuin activity and disrupts communication between different parts of cells and between organs like the brain and fat tissue, contributing to age-related decline and diseases.
- Recent research has strengthened the understanding of the NAD-sirtuin connection, leading to interest in NAD supplements as a potential way to combat aging-related issues.]
Top posts
Most liked on X and BlueskyIt takes two to tango: NAD+ and sirtuins in aging/longevity control #npjAMD https://t.co/Ev2HmvyRmO https://t.co/K9QJr9MwY5
> Lastly, sirtuins are major consumers of NAD and they require NAD to conduct their processes PMID 28721271: It takes two to tango: NAD+ and #sirtuins in aging/longevity control. NPJ Aging Mech Dis. 2016 https://t.co/O4mnFuiIEF PMID 27552971: Slowing ageing by design: the https://t.co/XbOCCzKHpa https://t.co/UrnZSrWsLj
It takes two to tango: NAD⁺ and sirtuins in aging/longevity control https://t.co/JrpLOQYFev
It takes two to tango: NAD+ and sirtuins in aging/longevity control | npj Aging
RT @Nature_NPJ: It takes two to tango: NAD+ and sirtuins in aging/longevity control #npjAMD https://t.co/Ev2HmvyRmO https://t.co/K9QJr9MwY5
All mentions
Impact of Exercise on Longevity and Cellular Aging Mechanisms
This video explores how physical activity influences aging and longevity by examining the roles of NAD and sirtuins, which are conserved mechanisms regulating cellular health and aging processes.
Boost NAD+ Levels to Combat Aging and Promote Longevity
Increasing NAD+ levels can reverse cellular signs of aging. Research highlights compounds like NMN, Resveratrol, and TMG that boost NAD+ to improve energy, cognitive function, and overall health, supporting longevity.
NAD+ and Aging: Natural Strategies to Enhance Cellular Health
NAD is essential for energy production, DNA repair, and cellular health. This video explores how aging reduces NAD levels and discusses natural methods to restore NAD, potentially slowing biological aging based on…
Enhancing NAD+ Levels to Fight Aging and Improve Cellular Health
Nicotinamide adenine dinucleotide NAD is a vital molecule responsible for energy production DNA repair and cellular health but declines with age. Replenishing NAD through NMN shows promise in mitigating age-related…
Nicotinamide Mononucleotide (NMN) and Its Role in Anti-Aging Therapy
This video explores Nicotinamide Mononucleotide (NMN), a precursor to NAD essential for energy, DNA repair, and cellular health. Studies show NMN supplementation can mitigate age-related declines in mice, supporting…
Boost NAD+ Levels to Combat Aging and Support Longevity
Increasing NAD+ can reverse cellular signs of aging. Research shows compounds like NMN, Resveratrol, and TMG help restore NAD, enhancing energy, cognition, and overall health, potentially promoting longer, healthier…
NAD+ and Aging: Strategies to Replenish Cellular Health and Longevity
Nicotinamide adenine dinucleotide NAD is a vital molecule responsible for energy production DNA repair and cellular health. Long-term NMN administration in mice reduces age-related decline by boosting NAD biosynthesis…
It takes two to tango: NAD⁺ and sirtuins in aging/longevity control https://t.co/JrpLOQYFev
It takes two to tango: NAD+ and sirtuins in aging/longevity control | npj Aging
> Lastly, sirtuins are major consumers of NAD and they require NAD to conduct their processes PMID 28721271: It takes two to tango: NAD+ and #sirtuins in aging/longevity control. NPJ Aging Mech Dis. 2016 https://t.co/O4mnFuiIEF PMID 27552971: Slowing ageing by design: the https://t.co/XbOCCzKHpa https://t.co/UrnZSrWsLj
Journal Reference: "It takes two to tango: NAD+ and sirtuins in aging/longevity control" Authors: Shin-Ichiro Imai, PhD, Leonard Guarente, PhD Afilliations: @WUSTLmed , @kochinstitute , @MIT Source Publication: @nature
RT @Nature_NPJ: It takes two to tango: NAD+ and sirtuins in aging/longevity control #npjAMD https://t.co/Ev2HmvyRmO https://t.co/K9QJr9MwY5
It takes two to tango: NAD+ and sirtuins in aging/longevity control #npjAMD https://t.co/Ev2HmvyRmO https://t.co/K9QJr9MwY5