Angew Chem Int Ed Engl September 2017 PMID 28763571

Enzymatic Synthesis of Psilocybin.

Janis Fricke, Felix Blei, Dirk Hoffmeister

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Mentions

Peak: 7 in Sep 2019

across 6 sources since Sep 2017

Extended reach

146,990

potential audience

Total likes

2,377

Video views

40,094

Mentions per month

Sep 2017 – Oct 2024

Where it's discussed

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AI synopsis

What people are saying

The readership shows curiosity about the enzyme mechanisms involved in psilocybin synthesis, as seen in mentions of the enzymes PsiD, PsiK, PsiM, and PsiH, and the potential for heterologous production. The tone remains informational, highlighting scientific progress without dramatic or contentious language to suggest high emotional engagement.

AgreementNeither agree nor disagree

The posts mostly acknowledge the scientific insights about psilocybin biosynthesis without strong disagreement, often noting previous research or the significance of the findings.

InterestModerate interest

There is moderate interest evident in the discussion of enzymes and molecular details, though some comments suggest curiosity rather than passionate enthusiasm.

EngagementModerate engagement

Posts demonstrate some engagement through referencing specific enzymes and research milestones, indicating a basic level of involvement.

ImpactModerate impact

Given the focus on enzymatic pathways and potential for biotechnological applications, the discussion hints at an impact on future research and development, but not a transformative shift yet.

Abstract in brief

The study identifies and characterizes four key enzymes involved in the biosynthesis of psilocybin from the magic mushroom Psilocybe, including a new type of fungal tryptophan decarboxylase and enzymes responsible for phosphotransfer, methylation, and oxidation steps.
Researchers successfully synthesized psilocybin using a combined enzyme reaction sequence from 4-hydroxytryptophan, creating a potentially cost-effective and stepwise biotechnological method.
These findings enhance understanding of psilocybin biosynthesis and could support its production for pharmaceutical uses, especially given the recent renewed interest in its medical applications.]

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All mentions

Synthetic Biology and Genetic Engineering of Psilocybin Producing E. coli

This video explores the biosynthesis and genetic modification of Escherichia coli to produce psilocybin, the psychoactive compound from magic mushrooms, and discusses the ethical implications of microbial genetic…

Alex Triptamina · Jan 6, 2024 39,776 views

Enzymatic Biosynthesis of Psilocybin in Psilocybe Mushrooms

This study characterizes four key enzymes involved in psilocybin biosynthesis from Psilocybe mushrooms, including a novel fungal tryptophan decarboxylase, and demonstrates a cost-effective enzymatic synthesis route from…

Elliot Cooper · Apr 30, 2021 318 views

Ray

@Ray46173426 · X

@TheDailyShroom Gene transfer of psilocybin making gene(s) into edible mushrooms, and other organisms, so they can't police it. Probably not harder than making LSD, with today's tek. Already done with yeast I think. https://t.co/ynWsW9BH3M

Jun 1, 2023 · 40 followers View post →

Tom

@pNauticExpress · X

RT @calyxlaw: Enzymatic basis for psilocybin biosynthesis shown by Janis Fricke, Felix Blei, & Dirk Hoffmeister They characterized four ps…

May 20, 2021 · 2 shares · 57,057 followers View post →

Psychedelic Alpha

@Psyched_Alpha · X

RT @calyxlaw: Enzymatic basis for psilocybin biosynthesis shown by Janis Fricke, Felix Blei, & Dirk Hoffmeister They characterized four ps…

May 20, 2021 · 2 shares · 20,747 followers View post →

Graham Pechenik

@graham_pechenik · X

May 20, 2021 · 9 likes · 2 shares · 5,656 followers View post →