Front Cardiovasc Med July 2017 PMID 28775986

The Effects of Serotonin in Immune Cells.

Nadine Herr, Christoph Bode, Daniel Duerschmied

Download social card

Mentions

50
Peak: 11 in Oct 2020
across 3 sources since Mar 2019

Extended reach

157,030
potential audience

Total likes

201

Video views

5,819

Mentions per month

Mar 2019 – Jun 2025

Where it's discussed

  • X / Twitter46 posts
  • YouTube2 videos
  • News2 articles

AI synopsis

What people are saying

The group discusses the biological role of serotonin in immune cells, with examples like the influence of serotonin on platelets and mast cells, and mentions potential implications for COVID-19 treatments. The tone ranges from scientifically detailed to speculative, reflecting both curiosity and caution about its real-world impact.

AgreementNeither agree nor disagree

Discussions show mixed opinions, with some acknowledging the research's relevance while others have doubts or focus on mechanisms, indicating no clear consensus.

InterestModerate interest

Many posts express curiosity about serotonin's role in immune responses and its implications for conditions like COVID-19, demonstrating moderate interest.

EngagementModerate engagement

Participants reference detailed mechanisms, like platelets and mast cells, and suggest practical applications, showing they are engaging at a technical level.

ImpactModerate impact

The posts suggest the study could influence understanding of immune-related treatments and COVID-19 responses, hinting at moderate potential impact.

Abstract in brief

  • Serotonin (5HT) is a crucial hormone circulating in the bloodstream, mainly stored in blood platelets, and influences various organs through different receptor subtypes, transporters, and protein interactions.
  • Almost all immune cells produce or respond to serotonin, which has been linked to immune regulation, such as modulating cytokine secretion in monocytes and macrophages, and influencing inflammation and immune cell activation.
  • Recent research highlights serotonin's role in immune responses, including suppressing certain cytokines like tumor necrosis factor and interleukin-1, as well as promoting neutrophil recruitment and T-cell activation.]

Top posts

Most liked on X and Bluesky
Heather Frushour
@HeatherFrushour · X

#Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral serotonin and impairs your lungs as well as your heart. #Quercetin and #Famotidine help this! See @farid__jalali for more! @WhiteHouse https://t.co/zRaFZ0VZa4

Oct 4, 2020 · 31 likes · 10 shares · 162 followers View post →
ice9
@__ice9 · X

More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: https://t.co/ivZUYntkSs Famotidine treats serotonin syndrome: https://t.co/WdusXIIeyu Mast cells contribute to releasing 5-HT: https://t.co/SZA7fTpMOy https://t.co/h2iCxfALCw https://t.co/O2F7YUGRTL

Jul 24, 2020 · 29 likes · 13 shares · 7,968 followers View post →
Crystal
@GemzME · X

@ItsAngInLA @ahandvanish The Effects of Serotonin in Immune Cells https://t.co/Ix1bLLtw7t

Jul 1, 2021 · 5 likes · 1,041 followers View post →
Fral
@__fral__ · X

@houndcl @__ice9 @ToddEBear @JuliaB_fitness @a_m_molenda @2dedostesta @jwmdebacker I highly recommend this reading: https://t.co/k1lSkmhv7O

Jul 6, 2020 · 3 likes · 24,558 followers View post →
Expose big pharma
@Pharmageddon24 · X

@abcsoka @iatrogenic_harm @SimonBreidert Good point. I was focusing on potential mechanisms through which SSRIs could possibly cause an autoimmune reaction underlying PSSD, but overlooked the fact that platelets don't have a nucleus. https://t.co/aZ2RHQiO4Q

Jun 8, 2023 · 3 likes · 8,541 followers View post →
ice9
@__ice9 · X

@nachkontrolle @farid__jalali However, platelets are believed to be the primary reservoir-- conveying 5-HT from enterochromaffin cells in the GI tract. https://t.co/xa1Rz7tstj https://t.co/SZA7fTpMOy Mast cells, activated T-lymphocytes, and possibly macrophages also synthesize it.

Aug 12, 2020 · 3 likes · 1 share · 7,968 followers View post →

All mentions

Diana
@PharmphoodTM · X

@InTime_49 @Brain1878 5HT2A https://t.co/FHveqXIwuw

Jun 8, 2025 · 1 like · 560 followers View post →
Crystal
@GemzME · X

@subversivepsych @Naomi_D_Harvey @Kirstycfsmelife It may not be just ssri, and an awareness of all sources and modifiers might also help with mood, if biochemical influencers of mood can be identified and moderated by other means. https://t.co/aFPDecMnCi https://t.co/PflMWN9XyW https://t.co/Tf1mqdiUIV

Oct 29, 2024 · 1,041 followers View post →
Crystal
@GemzME · X

@Paula_JKnight @AndrewG76201347 Yes, especially since it's a mast cell and platelets https://t.co/Tf1mqdjsyt and gut motility https://t.co/hHRkB7JxAE. and… and… and…

Sep 22, 2024 · 1 like · 1,041 followers View post →
Tat Yana
@Tat_Yana_13 · X

Frontiers | The Effects of Serotonin in Immune Cells https://t.co/z370TvboPj

Sep 11, 2024 · 19 followers View post →
Mikha’el
@LlamaAlloofs · X

RT @LlustriousLlama: @moreisdifferent @froglet80 @cfs_research @healingfromlc Back to your original topic https://t.co/Vm3nCgXmFm

Apr 30, 2024 · 1 share · 193 followers View post →
Mikha’el
@LlustriousLlama · X

RT @LlustriousLlama: @moreisdifferent @froglet80 @cfs_research @healingfromlc Back to your original topic https://t.co/Vm3nCgXmFm

Apr 30, 2024 · 1 share · 34 followers View post →
Mikha’el
@LlustriousLlama · X

@moreisdifferent @froglet80 @cfs_research @healingfromlc Back to your original topic https://t.co/Vm3nCgXmFm

Apr 30, 2024 · 1 share · 34 followers View post →
Diana
@PharmphoodTM · X

@sanilrege @AgnesAyton @psycheureka The Effects of Serotonin in Immune Cells https://t.co/WtwLPu2bT8

Jan 22, 2024 · 1 like · 560 followers View post →
Expose big pharma
@Pharmageddon24 · X

@abcsoka @iatrogenic_harm @SimonBreidert Good point. I was focusing on potential mechanisms through which SSRIs could possibly cause an autoimmune reaction underlying PSSD, but overlooked the fact that platelets don't have a nucleus. https://t.co/aZ2RHQiO4Q

Jun 8, 2023 · 3 likes · 8,541 followers View post →
Szyzygy
@Szyzygy2 · X

@exceedhergrasp1 @laurenancona https://t.co/6HVKTS2VsA

Jan 9, 2023 · 1 like · 1,172 followers View post →
Diana
@PharmphoodTM · X

@Jopo_dr @karimbrohi https://t.co/flRX5fUs1S

Dec 12, 2022 · 1 like · 560 followers View post →
Caroline
@carolineistanbu · X

@SofiaR2022 i suffered from MASC (hives) after the vaccine and also prepared my medicine cabinet to be ready in case of covid (SSRIs). in the process i came to wonder whether MASC may be secondary to low serotonin, as mast cells may release serotonin https://t.co/Wy4D19v2eu

Jun 1, 2022 · 2 likes · 246 followers View post →
7TZtopic
@5TZtopic · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Feb 2, 2022 · 13 shares · 992 followers View post →
7TZtopic
@5TZtopic · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Sep 6, 2021 · 13 shares · 992 followers View post →
Diana
@PharmphoodTM · X

@TEJUP @farid__jalali https://t.co/flRX5fTUck

Aug 15, 2021 · 2 likes · 560 followers View post →
Crystal
@GemzME · X

@ItsAngInLA @ahandvanish The Effects of Serotonin in Immune Cells https://t.co/Ix1bLLtw7t

Jul 1, 2021 · 5 likes · 1,041 followers View post →
Jacquesenboit
@jacquesenboit · X

@manorlaboratory @OgataAlana Nadine Herr, Christoph Bode & Daniel Duerschmied (2017) https://t.co/IkpGKvGNxo

May 24, 2021 · 2 likes · 638 followers View post →
syed shaban
@SydShaban · X

RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…

Dec 29, 2020 · 10 shares · 248 followers View post →
Sciortino Giuliano
@Giuliano1922 · X

THC will boost immunity against #COVID19 $TILT $TLLTF $TRUL $TCNNF $FFTNF $RWBYF $BMWLF $CURA $CURLF $TLRY $OH $LHS $OILS $LABS $KSHB $VFF $MMEN $GTII $GTBIF $HARV $CWEB $MEDIF $IAN $CVSI $GGB $NXGWF $NGW $MSOS https://t.co/jVCvdN1SDv

Dec 12, 2020 · 2 likes · 1,861 followers View post →
Canadian Association of Neuropathologists
@NeuropathCANP · X

RT @pdiamandisii: Check out our latest NeuroscIQ #educational lecture where we discuss how scientists are exploring how #neuroscience #sero…

Dec 7, 2020 · 1 share · 639 followers View post →
Phedias Diamandis
@pdiamandisii · X

Check out our latest NeuroscIQ #educational lecture where we discuss how scientists are exploring how #neuroscience #serotonin and #SSRI may help in the fight of #COVID19 #coronavirus #neuro #CNS #neuropath https://t.co/4URFOUZnzr

Dec 5, 2020 · 2 likes · 1 share · 683 followers View post →
EllieJellie2020
@EllieJellie2020 · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Oct 19, 2020 · 13 shares · 611 followers View post →
ice9
@__ice9 · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Oct 19, 2020 · 13 shares · 7,968 followers View post →
laserplus
@laserplus4 · X

RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…

Oct 7, 2020 · 10 shares · 49 followers View post →
Martine R.
@romromtin · X

RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…

Oct 6, 2020 · 10 shares · 1,469 followers View post →
KAH
@KHarris8182 · X

RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…

Oct 4, 2020 · 10 shares · 9,210 followers View post →
Joel Silveira Marchi
@joelsilveira · X

RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…

Oct 4, 2020 · 10 shares · 265 followers View post →
Minnie75
@sc_minnie75 · X

RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…

Oct 4, 2020 · 10 shares · 171 followers View post →
Carolien Hamming
@carolienhamming · X

RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…

Oct 4, 2020 · 10 shares · 679 followers View post →
Noris Kern
@KernNoris · X

RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…

Oct 4, 2020 · 10 shares · 76 followers View post →
Fral
@__fral__ · X

RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…

Oct 4, 2020 · 10 shares · 24,558 followers View post →
Heather Frushour
@HeatherFrushour · X

#Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral serotonin and impairs your lungs as well as your heart. #Quercetin and #Famotidine help this! See @farid__jalali for more! @WhiteHouse https://t.co/zRaFZ0VZa4

Oct 4, 2020 · 31 likes · 10 shares · 162 followers View post →
ice9
@__ice9 · X

@limits_stop @farid__jalali @SCCMPresident @DrMCecconi @2Scottish @iceman_ex @gsmartinmd @srrezaie @cameronks @LekshmiMD @progdoctalk I doubt it would persist long after inflammation and hypoxia resolve. It is mostly from pulmonary neuroendocrine cells and mast cells. https://t.co/5bhbchNWm5 https://t.co/HIZCcYXcKy https://t.co/SZA7fTHnG6 Triggers are airway hypoxia, inflammatory cytokines, histamine, etc.

Aug 30, 2020 · 7,968 followers View post →
CureME~CFS
@Cure_ME_CFS · X

RT @__ice9: @nachkontrolle @farid__jalali However, platelets are believed to be the primary reservoir-- conveying 5-HT from enterochromaffi…

Aug 12, 2020 · 1 share · 474 followers View post →
ice9
@__ice9 · X

@nachkontrolle @farid__jalali However, platelets are believed to be the primary reservoir-- conveying 5-HT from enterochromaffin cells in the GI tract. https://t.co/xa1Rz7tstj https://t.co/SZA7fTpMOy Mast cells, activated T-lymphocytes, and possibly macrophages also synthesize it.

Aug 12, 2020 · 3 likes · 1 share · 7,968 followers View post →
Jesse Valle
@m8o8r8e8n8a8z8o · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Jul 25, 2020 · 13 shares · 327 followers View post →
Carlos Dorta
@IntensiveDorta · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Jul 25, 2020 · 13 shares · 38 followers View post →
Danielle in ohio
@DvsBlack · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Jul 25, 2020 · 13 shares · 6,585 followers View post →
MakunuProff
@MakunuProff · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Jul 25, 2020 · 13 shares · 767 followers View post →
Benito Navarrete
@BenNavarrete · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Jul 24, 2020 · 13 shares · 599 followers View post →
Roshan
@Roshan_Karia · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Jul 24, 2020 · 13 shares · 312 followers View post →
Fral
@__fral__ · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Jul 24, 2020 · 13 shares · 24,558 followers View post →
Massato Hirai
@MassatoHirai · X

RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: ht…

Jul 24, 2020 · 13 shares · 106 followers View post →
ice9
@__ice9 · X

More reasons to use famotidine and montelukast in COVID-19 pneumonia-- H2 receptors promote platelet 5-HT uptake, clotting: https://t.co/ivZUYntkSs Famotidine treats serotonin syndrome: https://t.co/WdusXIIeyu Mast cells contribute to releasing 5-HT: https://t.co/SZA7fTpMOy https://t.co/h2iCxfALCw https://t.co/O2F7YUGRTL

Jul 24, 2020 · 29 likes · 13 shares · 7,968 followers View post →
Fral
@__fral__ · X

@houndcl @__ice9 @ToddEBear @JuliaB_fitness @a_m_molenda @2dedostesta @jwmdebacker I highly recommend this reading: https://t.co/k1lSkmhv7O

Jul 6, 2020 · 3 likes · 24,558 followers View post →
hardy limeback
@DrLimeback · X

@dantegiuliano The serotonin was raised in serum. Peripheral effects are very complex, mostly immune effects. https://t.co/xZJRQSv8EB So Lu et al study implicates #fluoride in both brain & peripheral serotonin effects. Public Health says #fluoridation is 'safe & effective' without any proof. https://t.co/4xKsHI2i4G

Mar 24, 2019 · 1,539 followers View post →
Journal Pone 0263035 | PDF | Single Nucleotide Polymorphism ...
News

https://doi.org/10.3389/fcvm.2017.00048 PMID: 28775986 70. Kang C-M, Kim H, Song JS, Choi B-J, Kim S-O, Jung H-S, et al. Genetic comparison ...

May 19, 2022 View →
What Is Serotonin and What Does It Do? | Psych Central
News

The effects of serotonin in immune cells. https://www.frontiersin.org/articles/10.3389/fcvm.2017.00048/full; Sadiq A, et al. (2018). The role ...

Jul 20, 2021 View →