The group discusses the biological role of serotonin in immune cells, with examples like the influence of serotonin on platelets and mast cells, and mentions potential implications for COVID-19 treatments. The tone ranges from scientifically detailed to speculative, reflecting both curiosity and caution about its real-world impact.
AgreementNeither agree nor disagree
Discussions show mixed opinions, with some acknowledging the research's relevance while others have doubts or focus on mechanisms, indicating no clear consensus.
InterestModerate interest
Many posts express curiosity about serotonin's role in immune responses and its implications for conditions like COVID-19, demonstrating moderate interest.
EngagementModerate engagement
Participants reference detailed mechanisms, like platelets and mast cells, and suggest practical applications, showing they are engaging at a technical level.
ImpactModerate impact
The posts suggest the study could influence understanding of immune-related treatments and COVID-19 responses, hinting at moderate potential impact.
Abstract in brief
Serotonin (5HT) is a crucial hormone circulating in the bloodstream, mainly stored in blood platelets, and influences various organs through different receptor subtypes, transporters, and protein interactions.
Almost all immune cells produce or respond to serotonin, which has been linked to immune regulation, such as modulating cytokine secretion in monocytes and macrophages, and influencing inflammation and immune cell activation.
Recent research highlights serotonin's role in immune responses, including suppressing certain cytokines like tumor necrosis factor and interleukin-1, as well as promoting neutrophil recruitment and T-cell activation.]
#Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral serotonin and impairs your lungs as well as your heart. #Quercetin and #Famotidine help this! See @farid__jalali for more! @WhiteHouse https://t.co/zRaFZ0VZa4
Oct 4, 2020 · 31 likes · 10 shares · 162 followersView post →
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ice9
@__ice9 · X
More reasons to use famotidine and montelukast in COVID-19 pneumonia--
H2 receptors promote platelet 5-HT uptake, clotting:
https://t.co/ivZUYntkSs
Famotidine treats serotonin syndrome:
https://t.co/WdusXIIeyu
Mast cells contribute to releasing 5-HT:
https://t.co/SZA7fTpMOy https://t.co/h2iCxfALCw https://t.co/O2F7YUGRTL
@abcsoka @iatrogenic_harm @SimonBreidert Good point. I was focusing on potential mechanisms through which SSRIs could possibly cause an autoimmune reaction underlying PSSD, but overlooked the fact that platelets don't have a nucleus.
https://t.co/aZ2RHQiO4Q
Jun 8, 2023 · 3 likes · 8,541 followersView post →
I
ice9
@__ice9 · X
@nachkontrolle @farid__jalali However, platelets are believed to be the primary reservoir-- conveying 5-HT from enterochromaffin cells in the GI tract.
https://t.co/xa1Rz7tstj
https://t.co/SZA7fTpMOy
Mast cells, activated T-lymphocytes, and possibly macrophages also synthesize it.
Aug 12, 2020 · 3 likes · 1 share · 7,968 followersView post →
This video explores how serotonin influences immune cells, modulating cytokine secretion, reducing inflammation, and potentially preventing COVID-19 progression. It discusses recent research on SSRIs like fluvoxamine…
Today I discuss serotonin and its significance in our body. Fibromyalgia patients often have low serotonin levels; we'll explore natural ways to boost it through diet, breathing, and meditation. Learn how serotonin…
@subversivepsych @Naomi_D_Harvey @Kirstycfsmelife It may not be just ssri, and an awareness of all sources and modifiers might also help with mood, if biochemical influencers of mood can be identified and moderated by other means.
https://t.co/aFPDecMnCi
https://t.co/PflMWN9XyW
https://t.co/Tf1mqdiUIV
@Paula_JKnight @AndrewG76201347 Yes, especially since it's a mast cell and platelets
https://t.co/Tf1mqdjsyt
and gut motility
https://t.co/hHRkB7JxAE.
and…
and…
and…
Sep 22, 2024 · 1 like · 1,041 followersView post →
TY
Tat Yana
@Tat_Yana_13 · X
Frontiers | The Effects of Serotonin in Immune Cells https://t.co/z370TvboPj
@abcsoka @iatrogenic_harm @SimonBreidert Good point. I was focusing on potential mechanisms through which SSRIs could possibly cause an autoimmune reaction underlying PSSD, but overlooked the fact that platelets don't have a nucleus.
https://t.co/aZ2RHQiO4Q
Jun 8, 2023 · 3 likes · 8,541 followersView post →
@SofiaR2022 i suffered from MASC (hives) after the vaccine and also prepared my medicine cabinet to be ready in case of covid (SSRIs). in the process i came to wonder whether MASC may be secondary to low serotonin, as mast cells may release serotonin https://t.co/Wy4D19v2eu
Check out our latest NeuroscIQ #educational lecture where we discuss how scientists are exploring how #neuroscience #serotonin and #SSRI may help in the fight of #COVID19 #coronavirus #neuro #CNS #neuropath https://t.co/4URFOUZnzr
Dec 5, 2020 · 2 likes · 1 share · 683 followersView post →
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EllieJellie2020
@EllieJellie2020 · X
RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia--
H2 receptors promote platelet 5-HT uptake, clotting:
ht…
Oct 19, 2020 · 13 shares · 611 followersView post →
I
ice9
@__ice9 · X
RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia--
H2 receptors promote platelet 5-HT uptake, clotting:
ht…
Oct 19, 2020 · 13 shares · 7,968 followersView post →
L
laserplus
@laserplus4 · X
RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…
RT @HeatherFrushour: #Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral seroton…
Oct 4, 2020 · 10 shares · 24,558 followersView post →
HF
Heather Frushour
@HeatherFrushour · X
#Covid-19 is a vascular disease and is hyper-activation of the platelets that then produce too much peripheral serotonin and impairs your lungs as well as your heart. #Quercetin and #Famotidine help this! See @farid__jalali for more! @WhiteHouse https://t.co/zRaFZ0VZa4
Oct 4, 2020 · 31 likes · 10 shares · 162 followersView post →
I
ice9
@__ice9 · X
@limits_stop @farid__jalali @SCCMPresident @DrMCecconi @2Scottish @iceman_ex @gsmartinmd @srrezaie @cameronks @LekshmiMD @progdoctalk I doubt it would persist long after inflammation and hypoxia resolve.
It is mostly from pulmonary neuroendocrine cells and mast cells.
https://t.co/5bhbchNWm5
https://t.co/HIZCcYXcKy
https://t.co/SZA7fTHnG6
Triggers are airway hypoxia, inflammatory cytokines, histamine, etc.
@nachkontrolle @farid__jalali However, platelets are believed to be the primary reservoir-- conveying 5-HT from enterochromaffin cells in the GI tract.
https://t.co/xa1Rz7tstj
https://t.co/SZA7fTpMOy
Mast cells, activated T-lymphocytes, and possibly macrophages also synthesize it.
Aug 12, 2020 · 3 likes · 1 share · 7,968 followersView post →
JV
Jesse Valle
@m8o8r8e8n8a8z8o · X
RT @__ice9: More reasons to use famotidine and montelukast in COVID-19 pneumonia--
H2 receptors promote platelet 5-HT uptake, clotting:
ht…
@dantegiuliano The serotonin was raised in serum. Peripheral effects are very complex, mostly immune effects. https://t.co/xZJRQSv8EB
So Lu et al study implicates #fluoride in both brain & peripheral serotonin effects. Public Health says #fluoridation is 'safe & effective' without any proof. https://t.co/4xKsHI2i4G