The collective discussions emphasize the bidirectional relationship between gut bacteria and sex hormones, with posts mentioning effects on health conditions like autoimmune diseases and depression, and theories about microbiome impacts in different sexes. The tone balances scientific insights with personal anecdotes, showing strong interest and belief that understanding this axis can lead to meaningful health improvements.
AgreementStrong agreement
Most discussions acknowledge the importance of the gut microbiome's influence on estrogen and overall health, strongly supporting the publication's implications.
InterestHigh interest
The posts demonstrate high curiosity, with many sharing personal experiences, facts, and implications of gut-hormone interactions.
EngagementModerate engagement
Participants engage actively by referencing research, personal stories, and broader health impacts, indicating thoughtful participation.
ImpactHigh impact
The discussions highlight the significant potential influence of gut microbiome health on disease and well-being, reflecting a belief in high practical and scientific importance.
Abstract in brief
The gut microbiome plays a crucial role in regulating circulating estrogens by producing an enzyme called glucuronidase, which activates estrogens; when gut microbiota are imbalanced (dysbiosis), this process is impaired, leading to lower estrogen levels that can affect various aspects of women's health.
Low estrogen levels linked to dysbiosis are associated with several health issues, including obesity, metabolic syndrome, certain cancers, reproductive disorders like PCOS and endometriosis, cardiovascular disease, and cognitive decline.
Therapeutic strategies such as bariatric surgery, metformin, dietary interventions, and microbiome modulation are promising ways to restore gut health and estrogen balance, potentially alleviating estrogen-driven diseases and improving overall health.
Did you know that your gut bacteria can affect your hormones?
The estrobolome can cause either estrogen excess or deficiency if out of balance.
This is why gut health is a key piece of the puzzle in terms of overall health, including hormone health!
https://t.co/83RLhh55kQ https://t.co/9vdf3idEvX
Dec 15, 2019 · 43 likes · 15 shares · 5,582 followersView post →
NP
Nicholas (@ultimape) Perry
@ultimape.bsky.wovensoup.com · Bluesky
Fun fact: gut bacteria are able to producing all of these things.
I had to to figure this out b/c I (as a cis male) have an estrogen imbalance tied to my (resolved) autoimmune diseases + major depression.
pubmed.ncbi.nlm.nih.gov/28778332
I can see infrared and am working on UV color perception.
@troonytoons Testosterone does not cause PMS, what an *diot.
Estrogens and microbiom in gut has health impacts and interactions for females.
https://t.co/P5sd8ojhBF
Who knows if males microbiom goes haywire with too much estrogen.
Dec 27, 2022 · 4 likes · 2,515 followersView post →
FB
François Booream
@BooraemFrancois · X
@EthicalSkeptic a good anecdote of dietary trend change in this period is is the podcast episode about mcdonald's frying oil from Revisionist History. https://t.co/JCvzilMGlh
Why this matters however is the dietary changes that occurred & how that effects microbiome. https://t.co/yiH5ihGCqj
Research shows that the gut microbiome regulates estrogen levels through the protein betaglucuronidase. Imbalances in gut bacteria can impair this process, affecting hormone balance and overall health. Learn about…
The gut microbiome plays a crucial role in regulating circulating estrogens through the enzyme glucuronidase. Imbalances can impair estrogen levels, affecting health issues like obesity, cancer, reproductive disorders…
The gut microbiome plays a crucial role in regulating circulating estrogens by producing an enzyme called glucuronidase, which activates estrogens; when gut microbiota are imbalanced (dysbiosis), this process is…
@SH2F088 @EmilybyNight there’s definitely bidirectional influence between gut bugs and sex hormones(in men and women!) https://t.co/cZZPGLiN4K
Aug 6, 2025 · 2 likes · 3,466 followersView post →
NP
Nicholas (@ultimape) Perry
@ultimape.bsky.wovensoup.com · Bluesky
Fun fact: gut bacteria are able to producing all of these things.
I had to to figure this out b/c I (as a cis male) have an estrogen imbalance tied to my (resolved) autoimmune diseases + major depression.
pubmed.ncbi.nlm.nih.gov/28778332
I can see infrared and am working on UV color perception.
@troonytoons Testosterone does not cause PMS, what an *diot.
Estrogens and microbiom in gut has health impacts and interactions for females.
https://t.co/P5sd8ojhBF
Who knows if males microbiom goes haywire with too much estrogen.
Dec 27, 2022 · 4 likes · 2,515 followersView post →
HD
Helen Driscoll
@HelenDriscoll · X
@behindthewoman1 @Rainbow_Poems @KathyBr18138930 Yes! I feel really good and helps mitigate what all my 'thrifty' genes would otherwise deliver :) I'm going to be 70 in 4 months so I've had some time to figure it out :)
https://t.co/wxET4xPSRu
@EthicalSkeptic a good anecdote of dietary trend change in this period is is the podcast episode about mcdonald's frying oil from Revisionist History. https://t.co/JCvzilMGlh
Why this matters however is the dietary changes that occurred & how that effects microbiome. https://t.co/yiH5ihGCqj
RT @wellbalanceND: Did you know that your gut bacteria can affect your hormones?
The estrobolome can cause either estrogen excess or defic…
Dec 15, 2019 · 15 shares · 1,466 followersView post →
SS
Sonya Satveit
@HormoneSoup · X
RT @wellbalanceND: Did you know that your gut bacteria can affect your hormones?
The estrobolome can cause either estrogen excess or defic…
Dec 15, 2019 · 15 shares · 1,911 followersView post →
TN
The Guv’nor
@SeanCodling · X
RT @wellbalanceND: Did you know that your gut bacteria can affect your hormones?
The estrobolome can cause either estrogen excess or defic…
Dec 15, 2019 · 15 shares · 1,557 followersView post →
K
KC
@KatC333 · X
RT @wellbalanceND: Did you know that your gut bacteria can affect your hormones?
The estrobolome can cause either estrogen excess or defic…
Dec 15, 2019 · 15 shares · 121 followersView post →
RS
Rosanne S
@Lydarose63 · X
RT @wellbalanceND: Did you know that your gut bacteria can affect your hormones?
The estrobolome can cause either estrogen excess or defic…
Dec 15, 2019 · 15 shares · 676 followersView post →
MD
Michelle Dowker
@wellbalanceND · X
Did you know that your gut bacteria can affect your hormones?
The estrobolome can cause either estrogen excess or deficiency if out of balance.
This is why gut health is a key piece of the puzzle in terms of overall health, including hormone health!
https://t.co/83RLhh55kQ https://t.co/9vdf3idEvX
Dec 15, 2019 · 43 likes · 15 shares · 5,582 followersView post →
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