J Nutr December 2017 PMID 28855419

Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial.

Imre Wk Kouw, Andrew M Holwerda, Jorn Trommelen, Irene Fleur Kramer, Jacqueline Bastiaanse, Shona L Halson, Will Kwh Wodzig, Lex B Verdijk, Luc Jc van Loon

Mentions

99
Peak: 35 in Aug 2023
across 4 sources since Apr 2020

Extended reach

1,917,821
potential audience

Total likes

61,199

Video views

1,782,638

Mentions per month

Apr 2020 – Oct 2025

Where it's discussed

  • X / Twitter70 posts
  • Facebook14 posts
  • News9 articles
  • YouTube6 videos

AI synopsis

What people are saying

Numerous discussions emphasize the importance of protein consumption before sleep, particularly focusing on the effectiveness of 40g of casein protein. The choice of words such as 'essential' and 'game changer' underscores their enthusiasm, suggesting that these insights could lead to meaningful changes in dietary habits for older adults. Many posts reference specific outcomes from the study, like the differing protein synthesis rates depending on the amount consumed, illustrating both detail and depth in their discussions.

AgreementStrong agreement

Most discussions express strong support for the findings, highlighting the benefits of pre-sleep protein ingestion.

InterestHigh interest

Participants show high curiosity regarding the implications of the study and its relevance to nutrition and aging.

EngagementModerate engagement

Some discussions delve into specific data and methods from the study, though many remain more surface-level.

ImpactHigh impact

There is a shared belief that the publication could greatly influence dietary practices among older adults.

Abstract in brief

  • Presleep protein ingestion, especially 40g of casein, enhances muscle protein synthesis rates in older men, counteracting age-related anabolic resistance.
  • In a study with 48 participants, those consuming 40g casein showed significantly higher protein synthesis rates compared to those consuming 20g casein or a placebo.
  • Overall, the findings suggest that eating protein before sleep is effectively digested and helps promote muscle growth during the night.

Top posts

Most liked on X and Bluesky
Jozo Grgic
@Jozo_Grgic · X

Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Overnight myofibrillar protein synthesis rates for the four conditions 33% 37% 39% 44% https://t.co/2pi7NVnYk8 https://t.co/rvgojGXjYW

Aug 8, 2023 · 187 likes · 43 shares · 5,469 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g of casein protein before sleep stimulates overnight muscle protein synthesis in healthy older adults. Our paper: https://t.co/CuapfA4l3W #protein #sleep https://t.co/s1cGncY8la

Jan 16, 2021 · 60 likes · 11 shares · 7,619 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

Throwback: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial Our Dec 2017 paper: https://t.co/CuapfA4l3W A thread with figures. 1/9 #protein #muscle #sleep https://t.co/gTw2VYXAIX

Dec 3, 2021 · 36 likes · 2 shares · 7,619 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight muscle protein synthesis in healthy older adults. Full breakdown: https://t.co/kbuQzx38N7 Study: https://t.co/CuapfA4l3W #protein #aging #muscle https://t.co/yNqrKnicBA

Apr 16, 2020 · 30 likes · 11 shares · 7,619 followers View post →
Dr. Anshul Sadhale
@AnshulGains · X

Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial https://t.co/SklnAMpd3V

Oct 2, 2023 · 8 likes · 2 shares · 14,122 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

In conclusion: consuming 40 g of casein protein right before sleep stimulates overnight muscle protein synthesis in healthy older adults. Paper: https://t.co/CuapfA4l3W

Dec 3, 2021 · 7 likes · 7,619 followers View post →

All mentions

eagleeye192020 Proud Hindu &Indian-Modi Ka Parivar
@eagleeye192020 · X

RT @AnshulGains: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Contr…

Sep 15, 2024 · 2 shares · 1,384 followers View post →
tokatti
@tokatti_ · X

20gのプロテインを飲んだグループは、水だけのグループに比べて15%筋肉のタンパク質合成が上がった。ただし、この数値は統計的に有意ではない https://t.co/hSKAsVxIVC 2012年の研究 似たような結果が出た https://t.co/QOJow3AgxO

Jun 26, 2024 · 178 followers View post →
!! I Wolf You
@MANISHNIFT · X

RT @AnshulGains: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Contr…

Oct 3, 2023 · 2 shares · 303 followers View post →
Dr. Anshul Sadhale
@AnshulGains · X

Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial https://t.co/SklnAMpd3V

Oct 2, 2023 · 8 likes · 2 shares · 14,122 followers View post →
Jared
@jives_pt · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 11, 2023 · 43 shares · 16 followers View post →
BIAC
@BIACRWC · X

Your night time snack should be protein https://t.co/z4sub0ReAm

Aug 10, 2023 · 443 followers View post →
Greg Grandgeorge
@T2MCoach · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 9, 2023 · 43 shares · 257 followers View post →
Jose
@Jose_8523 · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 9, 2023 · 43 shares · 293 followers View post →
Nutretxe | Sport Nutritionist
@Inakiem · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 9, 2023 · 43 shares · 59 followers View post →
The Phoenix Lab
@The_Phoenix_Lab · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 9, 2023 · 43 shares · 212 followers View post →
Eduardo Pérez de Lara
@laburramty · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 170 followers View post →
Raul
@RaulM06 · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 854 followers View post →
Skyler Tanner
@SkylerTanner · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 1,418 followers View post →
SV Sports Medicine
@svsuatc · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 785 followers View post →
Nitin Gandhi, M Pharm
@NitinGa35829582 · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 358 followers View post →
Mario Coronado
@MarioCo57217417 · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 104 followers View post →
Koushik
@koushikphysio · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 519 followers View post →
J. García-Liñeira
@JesusLinheira · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 371 followers View post →
El Taquicardio
@TaquicardioMD · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 273 followers View post →
Mesha
@cosmautic · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 460 followers View post →
Barbagianni
@BarbaGian_ · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 46 followers View post →
John T Weatherly
@jtwheat27 · X

Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomize… https://t.co/QGMJcWtEvq This wqs pub in 2017. I wonder how many more studies have been done since or are going to be done? You'd think this could get funding?

Aug 8, 2023 · 1 like · 5,009 followers View post →
Javed Alam
@jalam1001 · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 996 followers View post →
GDLeahy
@GDLeahy · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 679 followers View post →
Carlos García (Lalo)
@CarlosEGZ95 · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 5 followers View post →
renata_schwartz
@re_schwartz · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 129 followers View post →
Scott
@show_scott22 · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 244 followers View post →
John Paul Catanzaro
@catanzarogroup · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 748 followers View post →
Wunder
@bright_okeye · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 95 followers View post →
Mark hughes
@Physiomark2 · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 135 followers View post →
Cristian Solis Mencia
@CSolis_Mencia · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 80 followers View post →
daniel venancio
@paulinovenancio · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 178 followers View post →
FuzeSiravit
@fuzesiravit · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 88 followers View post →
Arnau Manzano
@A_manzano4 · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 170 followers View post →
Abramo coach
@coach_abramo · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 75 followers View post →
SmartNutrition
@SmartNutrition1 · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 2,657 followers View post →
Goodhealth_._
@CroxFit · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 346 followers View post →
Zack
@keychupkicap · X

RT @Jozo_Grgic: Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Ove…

Aug 8, 2023 · 43 shares · 389 followers View post →
Jozo Grgic
@Jozo_Grgic · X

Protein ingestion before sleep No protein 20 g casein protein 20 g casein protein + 1.5 g leucine 40 g casein protein Overnight myofibrillar protein synthesis rates for the four conditions 33% 37% 39% 44% https://t.co/2pi7NVnYk8 https://t.co/rvgojGXjYW

Aug 8, 2023 · 187 likes · 43 shares · 5,469 followers View post →
De Sportschool
@DeSportschool · X

RT @JornTrommelen: In conclusion, consuming 40 g of casein protein right before sleep stimulates overnight muscle protein synthesis in heal…

May 31, 2022 · 1 share · 451 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

In conclusion, consuming 40 g of casein protein right before sleep stimulates overnight muscle protein synthesis in healthy older adults. However, 20 g of casein is not enough to see this effect. Our study: https://t.co/CuapfA4l3W Follow us on Instagram: https://t.co/VBgqiIoxNF https://t.co/2O67TCnNvJ

May 31, 2022 · 3 likes · 1 share · 7,619 followers View post →
OJSN
@iamojsn · X

RT @JornTrommelen: Throwback: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Ran…

Dec 4, 2021 · 2 shares · 14,963 followers View post →
Weldon
@Rocker75W · X

RT @JornTrommelen: Throwback: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Ran…

Dec 3, 2021 · 2 shares · 330 followers View post →
Matt Jones
@MattJonesNC · X

RT @JornTrommelen: Throwback: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Ran…

Dec 3, 2021 · 2 shares · 3,557 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

In conclusion: consuming 40 g of casein protein right before sleep stimulates overnight muscle protein synthesis in healthy older adults. Paper: https://t.co/CuapfA4l3W

Dec 3, 2021 · 7 likes · 7,619 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

Throwback: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial Our Dec 2017 paper: https://t.co/CuapfA4l3W A thread with figures. 1/9 #protein #muscle #sleep https://t.co/gTw2VYXAIX

Dec 3, 2021 · 36 likes · 2 shares · 7,619 followers View post →
Walter Adamson
@bodyagebuster · X

Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men: A Randomized Controlled Trial https://t.co/0lqvYsAEu1 > 40g #protein before bed #research #nutrition https://t.co/b9N3wFQcQk

Feb 6, 2021 · 1 like · 584 followers View post →
Shannon Fizer, M.Sc.
@shannon_fizer · X

RT @JornTrommelen: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g o…

Jan 17, 2021 · 11 shares · 150 followers View post →
trnutri
@tr_nutricionist · X

RT @JornTrommelen: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g o…

Jan 17, 2021 · 11 shares · 58 followers View post →
Weldon
@Rocker75W · X

RT @JornTrommelen: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g o…

Jan 16, 2021 · 11 shares · 330 followers View post →
Steven Phu
@phu_steven · X

RT @JornTrommelen: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g o…

Jan 16, 2021 · 11 shares · 216 followers View post →
Víctor Toscano
@Vic_Tos19 · X

RT @JornTrommelen: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g o…

Jan 16, 2021 · 11 shares · 7,899 followers View post →
Cindy Kugler
@Exspec85 · X

RT @JornTrommelen: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g o…

Jan 16, 2021 · 11 shares · 234 followers View post →
Ale ❤️‍
@alejandravelezg · X

RT @JornTrommelen: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g o…

Jan 16, 2021 · 11 shares · 1,112 followers View post →
David Scott
@DavidScottPhD · X

RT @JornTrommelen: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g o…

Jan 16, 2021 · 11 shares · 2,950 followers View post →
lopo
@Tonylopo · X

RT @JornTrommelen: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g o…

Jan 16, 2021 · 11 shares · 732 followers View post →
Frederic Danel
@Frederic_Danel · X

RT @JornTrommelen: Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g o…

Jan 16, 2021 · 11 shares · 332 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

Protein Ingestion before Sleep Increases Overnight Muscle Protein Synthesis Rates in Healthy Older Men Consuming 40 g of casein protein before sleep stimulates overnight muscle protein synthesis in healthy older adults. Our paper: https://t.co/CuapfA4l3W #protein #sleep https://t.co/s1cGncY8la

Jan 16, 2021 · 60 likes · 11 shares · 7,619 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

@GDLeahy Older adults typically need more protein per meal moment compared to younger adults. But we have shown 40 g of pre-sleep protein to be effective in older adults (whether more is better is unknown, but probably not practical anyway). https://t.co/CuapfzMJFm

Jul 27, 2020 · 2 likes · 7,619 followers View post →
Victor H.
@vickh90 · X

RT @JornTrommelen: Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight…

May 26, 2020 · 11 shares · 38 followers View post →
Camilo Rincón
@crincony · X

https://t.co/sLszwLEfYA 40 gramos de caseína (proteina) estimula la síntesis proteica antes de dormir en adultos mayores

Apr 17, 2020 · 1 like · 130 followers View post →
International Protein Board
@ProteinBoard · X

RT @JornTrommelen: Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight…

Apr 17, 2020 · 11 shares · 412 followers View post →
Raul
@RaulM06 · X

RT @JornTrommelen: Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight…

Apr 17, 2020 · 11 shares · 854 followers View post →
Daniel P. Fitze
@DPFitze · X

RT @JornTrommelen: Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight…

Apr 16, 2020 · 11 shares · 53 followers View post →
dmcabler
@dmcabler · X

RT @JornTrommelen: Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight…

Apr 16, 2020 · 11 shares · 255 followers View post →
Dr. Myohead
@DrMyohead · X

RT @JornTrommelen: Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight…

Apr 16, 2020 · 11 shares · 2,644 followers View post →
Claudio Chinaglia
@claudiochinagli · X

RT @JornTrommelen: Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight…

Apr 16, 2020 · 11 shares · 118 followers View post →
Eric Rawson, Ph.D.
@EricRawsonPhD · X

RT @JornTrommelen: Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight…

Apr 16, 2020 · 11 shares · 7,540 followers View post →
PT_Thunem
@PT_Thunem · X

RT @JornTrommelen: Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight…

Apr 16, 2020 · 11 shares · 80 followers View post →
Jorn Trommelen, PhD
@JornTrommelen · X

Pre-sleep protein beneficial for older adults? Consuming 40 g of casein protein right before sleep stimulates overnight muscle protein synthesis in healthy older adults. Full breakdown: https://t.co/kbuQzx38N7 Study: https://t.co/CuapfA4l3W #protein #aging #muscle https://t.co/yNqrKnicBA

Apr 16, 2020 · 30 likes · 11 shares · 7,619 followers View post →