Chronic Stress (Thousand Oaks) April 2017 PMID 28856337

Neurobiological and Systemic Effects of Chronic Stress.

Bruce S McEwen

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Mentions

157
Peak: 4 in Nov 2022
across 6 sources since Sep 2020

Extended reach

689,563
potential audience

Total likes

25,212

Video views

630,903

Mentions per month

Sep 2020 – Oct 2025

Where it's discussed

  • News93 articles
  • X / Twitter36 posts
  • YouTube10 videos
  • Facebook9 posts
  • Blogs8 articles
  • Bluesky1 posts

AI synopsis

What people are saying

The overall tone reflects a recognition of the article’s importance, with specific references to neurobiological concepts like brain plasticity and allostasis, yet many discussions remain surface-level or include unrelated comments, which limits depth of engagement but still demonstrates some awareness of the article’s significance.

AgreementModerate agreement

Many discussions acknowledge the significance of the article, with some referencing its insights into stress effects on the brain and systemic health, indicating general agreement on its importance.

InterestModerate interest

The social discussions show curiosity about the topic, with several posts mentioning specific concepts like allostasis and neuroplasticity, but overall interest appears moderate.

EngagementNeutral engagement

While some posts reference the research directly, such as noting systemic effects and neurobiological responses, others are more superficial or contain off-topic comments, leading to a neutral engagement level.

ImpactModerate impact

The discussions suggest that the article prompts reflection on stress health impacts, with some sharing personal insights or highlighting implications, but there is no widespread evidence of deep influence or calls to action.

Abstract in brief

  • The brain plays a central role in how we perceive and respond to stress, helping us adapt but also risking long-term health problems if stress becomes overwhelming or dysregulated.
  • Stress can cause changes in the brain's structure and function, affecting how we think, decide, and feel, which in turn impacts bodily systems like hormones and immune responses.
  • There are important differences based on sex and early life experiences that influence stress responses, but because the brain is plastic, therapies and policies can help promote health and resilience over time.]

Top posts

Most liked on X and Bluesky
Dr. MeDeseas
@DrDhelizioso · X

@agulayya @doctormacias Pobre p€ndejazo primaria trunca. https://t.co/WLefDJJOoO “Doctor en enfermería” Jajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajjajajajajajajajajajajajaj

Jul 28, 2023 · 16 likes · 2,828 followers View post →
FND Portal - is no longer on X
@FndPortal · X

But there’s also a less familiar one: persistent changes to allostasis in the brain. Again, allostasis is the brains predictive handling of physical and psychological challenges. Which are handled by a common system. https://t.co/vzqNBz1uYp

Nov 6, 2022 · 3 likes · 1 share · 6,943 followers View post →
Psicología
@psyredterapia · X

Source : https://t.co/CZcmBd6wbS and https://t.co/otucyoBFC3

Feb 25, 2025 · 3 likes · 1 share · 3,772 followers View post →
Psy Red
@psyredorg · X

Source : https://t.co/CZcmBd6wbS and https://t.co/otucyoBFC3

Feb 25, 2025 · 3 likes · 1 share · 3,678 followers View post →
Sage Psychology
@SagePsychology · X

What are the #neurobiological and systemic effects of chronic #stress? @Chronic_Stress https://t.co/9ZoyprPmHw

Sep 22, 2020 · 2 likes · 12,279 followers View post →
Sage Clinical Med
@SageClinMed · X

Read this most read #openaccess article from Chronic Stress on systemic effects of #chronic #stress. @Chronic_Stress https://t.co/8CGg7nHhid

Jul 4, 2021 · 1 like · 3,274 followers View post →

All mentions

Attached | Feel fear / anxiety in relationships?
@attached_app · X

McEwen BS (2017). Neurobiological and systemic effects of chronic stress. Neuropsychopharmacology, 42(1), 1-4 Kolassa IT & Elbert T (2007). Structural and functional neuroplasticity in PTSD. Neuroscience & Biobehavioral Reviews, 31(4), 537-543

Oct 27, 2025 · 37 followers View post →
Fabio
@germ_86 · X

Mar 6, 2025 · 230 followers View post →
cuerpocalloso
@barbaricyawp02 · X

RT @psymindfact: Source : https://t.co/CZcmBd6wbS and https://t.co/otucyoBFC3

Mar 3, 2025 · 1 share · 79 followers View post →
Psicología
@psyredterapia · X

Source : https://t.co/CZcmBd6wbS and https://t.co/otucyoBFC3

Feb 25, 2025 · 3 likes · 1 share · 3,772 followers View post →
Psy Red
@psyredorg · X

Source : https://t.co/CZcmBd6wbS and https://t.co/otucyoBFC3

Feb 25, 2025 · 3 likes · 1 share · 3,678 followers View post →
Teresa UN; views my own.
@shufti.bsky.social · Bluesky

"This dysregulated state may result in the development of mood disorders but the process by which this occurs is still unknown." Clue: "Neurobiological and Systemic Effects of Chronic #Stress" pmc.ncbi.nlm.nih.gov/articles/PMC... Overload of triggers, past/present trauma, reduced resilience is key

Nov 18, 2024 · 1 like View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

Apr 18, 2024 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

Apr 8, 2024 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQCvI via @NCBI

Mar 5, 2024 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

Feb 28, 2024 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

Jan 9, 2024 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

Dec 24, 2023 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

Nov 14, 2023 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

Aug 5, 2023 · 491 followers View post →
Dr. MeDeseas
@DrDhelizioso · X

@agulayya @doctormacias Pobre p€ndejazo primaria trunca. https://t.co/WLefDJJOoO “Doctor en enfermería” Jajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajajjajajajajajajajajajajajaj

Jul 28, 2023 · 16 likes · 2,828 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

Jun 11, 2023 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NIH

May 29, 2023 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

May 20, 2023 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

May 15, 2023 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

May 7, 2023 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

Apr 14, 2023 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NIH

Feb 12, 2023 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQCvI via @NCBI

Jan 26, 2023 · 491 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga via @NCBI

Dec 15, 2022 · 491 followers View post →
Tracy Taylor
@modeltweaker · X

RT @boretrol: Neurobiological and Systemic Effects of Chronic Stress https://t.co/AInorW1zz7

Nov 7, 2022 · 1 share · 646 followers View post →
Robert Olney
@boretrol · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/AInorW1zz7

Nov 7, 2022 · 1 like · 1 share · 1,660 followers View post →
Robert Olney
@boretrol · X

RT @FndPortal: But there’s also a less familiar one: persistent changes to allostasis in the brain. Again, allostasis is the brains predic…

Nov 7, 2022 · 1 share · 1,660 followers View post →
FND Portal - is no longer on X
@FndPortal · X

But there’s also a less familiar one: persistent changes to allostasis in the brain. Again, allostasis is the brains predictive handling of physical and psychological challenges. Which are handled by a common system. https://t.co/vzqNBz1uYp

Nov 6, 2022 · 3 likes · 1 share · 6,943 followers View post →
Jonathan Joseph
@jonathanj92389 · X

Neurobiological and Systemic Effects of Chronic Stress https://t.co/sBmvSRQ4Ga

Aug 23, 2022 · 491 followers View post →
Frances Bernard
@Fran_Bernard · X

As it turns out taking hormones like higher doses in the past birth control pills for years had a lot of unforeseen serious negative side effects. Neurobiological and Systemic Effects of Chronic Stress - Bruce S. McEwen, 2017 https://t.co/58T6ORC4kA

May 1, 2022 · 32 followers View post →
Sage Clinical Med
@SageClinMed · X

Read this most read #openaccess article from Chronic Stress on systemic effects of #chronic #stress. @Chronic_Stress https://t.co/8CGg7nHhid

Jul 4, 2021 · 1 like · 3,274 followers View post →
Dark Brandon Rises
@iamgabbarson · X

RT @SAGEHealthInfo: Read this most read #openaccess article from Chronic Stress on systemic effects of #chronic #stress. @Chronic_Stress ht…

Jul 4, 2021 · 1 share · 544 followers View post →
Sage Health & Nursing
@SageHealthInfo · X

Read this most read #openaccess article from Chronic Stress on systemic effects of #chronic #stress. @Chronic_Stress https://t.co/2jkUpQ4bjF

Jul 4, 2021 · 1 share · 5,037 followers View post →
Manya
@happylilhumann · X

So I was asked to make a biology project and I chose “Neurobiological and systemic effects of chronic stress” Myocardial Infraction side effects

Jun 3, 2021 · 1 like · 1,567 followers View post →
Side hustles and paid gigs
@Paid_online_gig · X

RT SAGEpsychology What are the #neurobiological and systemic effects of chronic #stress? @Chronic_Stress https://t.co/pDhXNPzIqZ

Sep 22, 2020 · 503 followers View post →
Sage Psychology
@SagePsychology · X

What are the #neurobiological and systemic effects of chronic #stress? @Chronic_Stress https://t.co/9ZoyprPmHw

Sep 22, 2020 · 2 likes · 12,279 followers View post →
Sage Health & Nursing
@SageHealthInfo · X

What are the #neurobiological and systemic effects of chronic #stress? @Chronic_Stress https://t.co/pS3U56dBB3

Sep 22, 2020 · 5,037 followers View post →