Association between metabolic syndrome and intravesical prostatic protrusion in patients with benign prostatic enlargement and lower urinary tract symptoms (MIPS Study).

Giorgio I Russo, Federica Regis, Pietro Spatafora, Jacopo Frizzi, Daniele Urzì, Sebastiano Cimino, Sergio Serni, Marco Carini, Mauro Gacci, Giuseppe Morgia

May 2018 BJU Int

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Metabolic Syndrome's Impact on Prostate Enlargement and Symptoms

Metabolic Syndrome's Impact on Prostate Enlargement and Symptoms

The study explores the link between metabolic syndrome and prostate features like intravesical protrusion, volume, and severity of urinary symptoms, highlighting the influence of factors such as HDL cholesterol and hypertension on prostate health.

BJUI

May 10, 2018

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Abstract Synopsis

  • The study found that patients with metabolic syndrome (MetS) showed larger prostate features such as intravesical prostatic protrusion (IPP), total prostate volume (TPV), and transitional zone volume (TZV), suggesting a link between MetS and benign prostatic enlargement (BPE).
  • Certain factors like high-density lipoprotein (HDL) cholesterol levels and hypertension were independently associated with prostate measurements, with high HDL being linked to smaller prostate size and hypertension to larger prostate features.
  • Overall, the research suggests that metabolic syndrome is connected to changes in prostate morphology, especially increased IPP, which may impact the severity of lower urinary tract symptoms in men with BPE.]