BJU Int May 2018 PMID 28872764

Association between metabolic syndrome and intravesical prostatic protrusion in patients with benign prostatic enlargement and lower urinary tract symptoms (MIPS Study).

Giorgio I Russo, Federica Regis, Pietro Spatafora, Jacopo Frizzi, Daniele Urzì, Sebastiano Cimino, Sergio Serni, Marco Carini, Mauro Gacci, Giuseppe Morgia

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Abstract in brief

  • The study found that patients with metabolic syndrome (MetS) showed larger prostate features such as intravesical prostatic protrusion (IPP), total prostate volume (TPV), and transitional zone volume (TZV), suggesting a link between MetS and benign prostatic enlargement (BPE).
  • Certain factors like high-density lipoprotein (HDL) cholesterol levels and hypertension were independently associated with prostate measurements, with high HDL being linked to smaller prostate size and hypertension to larger prostate features.
  • Overall, the research suggests that metabolic syndrome is connected to changes in prostate morphology, especially increased IPP, which may impact the severity of lower urinary tract symptoms in men with BPE.]

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