September 2017 PMID 28912502

Caloric restriction delays age-related methylation drift.

Shinji Maegawa, Yue Lu, Tomomitsu Tahara, Justin T Lee, Jozef Madzo, Shoudan Liang, Jaroslav Jelinek, Ricki J Colman, Jean-Pierre J Issa

Mentions

85
Peak: 2 in Mar 2022
across 6 sources since Mar 2021

Extended reach

50,941
potential audience

Total likes

72

Video views

1,235

Mentions per month

Mar 2021 – Jun 2025

Where it's discussed

  • News33 articles
  • Facebook29 posts
  • Blogs12 articles
  • Reddit5 posts
  • X / Twitter4 posts
  • YouTube2 videos

AI synopsis

What people are saying

The overall tone demonstrates a positive reception, with discussions emphasizing the study's importance, such as mentions of the conservation of methylation drift across species and how caloric restriction might prolong healthspan. The language reveals curiosity and acknowledgment of the research’s potential to influence aging science, with phrases like 'delays age-related changes' and 'conserved across species' conveying both scientific interest and perceived significance.

AgreementModerate agreement

Most discussions acknowledge the significance of the study, emphasizing its potential benefits for aging and health.

InterestModerate interest

Participants show moderate interest, highlighting the relevance of caloric restriction and its biological effects.

EngagementModerate engagement

Posts engage with the scientific findings, referencing details like conservation across species and methylation drift rates.

ImpactModerate impact

The discussions reflect an optimistic view of the study's implications for aging research and potential health interventions.

Abstract in brief

  • Caloric restriction (CR) has been shown to extend lifespan in mammals and appears to slow down age-related changes in DNA methylation, known as methylation drift.
  • The study found that this methylation drift is conserved across species like mice, rhesus monkeys, and humans, and its rate correlates with lifespan.
  • In animals subjected to CR, the age-related methylation changes were reduced, making their epigenetic age appear younger than their actual age, suggesting that CR may help preserve epigenetic health and influence aging.

Top posts

Most liked on X and Bluesky
Agingdoc
@agingdoc1 · X

Caloric restriction delays age-related methylation drift (2017) https://t.co/aP6zZPzuTG "...we report that epigenetic drift is conserved across species and the rate of drift correlates with lifespan when comparing mice, rhesus monkeys, and humans..."

Mar 23, 2022 · 1 like · 1 share · 42,612 followers View post →
Shoko Kimura,Aniie
@Ani_9_ · X

健康診断のためにファスティングして、4日で体重-5kg達成。 断食を適度にするのは良い。科学も証明している! Caloric restriction delays age-related methylation drift in rhesus monkeys 食事の30%カロリーダウンは、若く見える分子的証拠が得られた。 https://t.co/H4uqisWeRH

Jun 10, 2025 · 3,507 followers View post →
Shoko Kimura,Aniie
@Ani_9_ · X

健康診断のためにファスティングして、4日で体重-5kg達成。 断を適度にするのは良い。科学も証明している! Caloric restriction delays age-related methylation drift in rhesus monkeys 食事の30%カロリーダウンは、若く見える分子的証拠が得られた。 https://t.co/H4uqisWeRH

Jun 10, 2025 · 3,507 followers View post →
Carlos Colmenero
@colme99 · X

RT @agingdoc1: Caloric restriction delays age-related methylation drift (2017) https://t.co/aP6zZPzuTG "...we report that epigenetic drif…

Mar 23, 2022 · 1 share · 77 followers View post →

All mentions

Shoko Kimura,Aniie
@Ani_9_ · X

健康診断のためにファスティングして、4日で体重-5kg達成。 断食を適度にするのは良い。科学も証明している! Caloric restriction delays age-related methylation drift in rhesus monkeys 食事の30%カロリーダウンは、若く見える分子的証拠が得られた。 https://t.co/H4uqisWeRH

Jun 10, 2025 · 3,507 followers View post →
Shoko Kimura,Aniie
@Ani_9_ · X

健康診断のためにファスティングして、4日で体重-5kg達成。 断を適度にするのは良い。科学も証明している! Caloric restriction delays age-related methylation drift in rhesus monkeys 食事の30%カロリーダウンは、若く見える分子的証拠が得られた。 https://t.co/H4uqisWeRH

Jun 10, 2025 · 3,507 followers View post →
Carlos Colmenero
@colme99 · X

RT @agingdoc1: Caloric restriction delays age-related methylation drift (2017) https://t.co/aP6zZPzuTG "...we report that epigenetic drif…

Mar 23, 2022 · 1 share · 77 followers View post →
Agingdoc
@agingdoc1 · X

Caloric restriction delays age-related methylation drift (2017) https://t.co/aP6zZPzuTG "...we report that epigenetic drift is conserved across species and the rate of drift correlates with lifespan when comparing mice, rhesus monkeys, and humans..."

Mar 23, 2022 · 1 like · 1 share · 42,612 followers View post →