Curr Atheroscler Rep September 2017 PMID 28921056

Oxidative Stress in Atherosclerosis.

Ajoe John Kattoor, Naga Venkata K Pothineni, Deepak Palagiri, Jawahar L Mehta

Mentions

51
Peak: 16 in Aug 2019
across 4 sources since Mar 2019

Extended reach

363,981
potential audience

Total likes

363

Video views

6,548

Mentions per month

Mar 2019 – Nov 2024

Where it's discussed

  • X / Twitter44 posts
  • Facebook3 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

The discussions predominantly focus on the mechanistic aspects of oxidative stress, such as the role of NOX1 and eNOS uncoupling, with examples like the mention of olive oil compounds’ vasculoprotective effects and the connection between oxidative stress and inflammation. The tone mixes scientific detail with curiosity, reflecting a proactive interest but limited deep engagement in policy or clinical application, resulting in moderate impact scores.

AgreementModerate agreement

Most discussions acknowledge the role of oxidative stress in atherosclerosis, with some emphasizing mechanisms like eNOS uncoupling and NOX1 activity, indicating general agreement with the publication’s focus.

InterestHigh interest

The topics cover a range of related mechanisms and potential therapies, which suggests high interest among participants in emerging research and treatment strategies.

EngagementModerate engagement

Comments include specific references to mechanisms, such as antioxidants and cellular processes, showing a moderate level of engagement with the scientific content.

ImpactModerate impact

While some posts emphasize the importance of oxidative stress and potential therapeutic targets, the overall impact appears moderate, as discussions are mostly exploratory and informational rather than advocacy-driven.

Abstract in brief

  • Atherosclerosis is now viewed as a chronic inflammatory disease where oxidative stress, caused by excess reactive oxygen species (ROS), plays a key role in its development and progression; the imbalance between ROS and antioxidants leads to vascular injury.
  • Although traditional risk factors contribute to oxidative stress in atherosclerosis, clinical trials with antioxidant supplements have largely been unsuccessful, prompting research into advanced therapies like mitochondrial-targeted ROS scavengers, nanotechnology, gene therapy, and specific inhibitors such as synthetic LOX1 modulators.
  • Current treatments like aspirin, statins, and renin-angiotensin system inhibitors provide some antioxidative benefits, and there is ongoing exploration of new therapeutic strategies aimed at selectively reducing oxidative stress to better manage atherosclerotic vascular disease.

Top posts

Most liked on X and Bluesky
Frontiers
@FrontiersIn · X

Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stress in #atherosclerosis, as well as possible treatments for #antioxidative stress. #openaccess review @FrontPhysiol; read & download: https://t.co/iNamYc7VFQ https://t.co/TdIlMmUb1U

Jun 19, 2019 · 70 likes · 25 shares · 90,067 followers View post →
Glen Pyle | #WomensHeartHealth ❤️‍
@glenpyle · X

NOXal action: #NOX1 links Endothelin-1 & pro-inflammatory #oxidative stress in #atherosclerosis. @AnastasiaSMihai @_atanas_ @KateyRayner @prof_brunt https://t.co/pIXA598lA0

Oct 23, 2020 · 19 likes · 5 shares · 7,243 followers View post →
Cells MDPI
@Cells_MDPI · X

Jan 26, 2024 · 2 likes · 3,040 followers View post →
Cells MDPI
@Cells_MDPI · X

Aug 25, 2023 · 2 likes · 1 share · 3,040 followers View post →
Novus Biologicals, a Bio-Techne brand
@novusbio · X

New #Science Blog: New study connects atherosclerotic plaque buildup to leaky gut and #microbiome derived LPS, implicating TLR4-mediated oxidative stress in #atherosclerosis. Read More: https://t.co/GPBAl5aipZ https://t.co/jjbYSrV0xg

Mar 26, 2019 · 1 like · 3,113 followers View post →
Cells MDPI
@Cells_MDPI · X

Sep 10, 2024 · 1 like · 3,040 followers View post →

All mentions

Peter J Anderson
@PeterJAnderson_ · X

@lipo_fan @JeffA000 @DudzLightLime @_earthling74 @NutritionMadeS3 “eNOS uncoupling appears to be an important mechanism contributing to increased oxidative stress in atherosclerosis.”

Nov 28, 2024 · 1,588 followers View post →
Cells MDPI
@Cells_MDPI · X

Sep 10, 2024 · 1 like · 3,040 followers View post →
Dr Anthony Martin
@AMAinsight · X

Cells | Free Full-Text | The Role of Oxidative Stress in Atherosclerosis https://t.co/QT3YFaAMtu

Jul 16, 2024 · 920 followers View post →
Cells MDPI
@Cells_MDPI · X

Jan 26, 2024 · 2 likes · 3,040 followers View post →
RAKESH JAIN
@jainrakesh3151 · X

RT @Cells_MDPI:

Aug 30, 2023 · 1 share · 193 followers View post →
Cells MDPI
@Cells_MDPI · X

Aug 25, 2023 · 2 likes · 1 share · 3,040 followers View post →
Dan Purser MD
@RealDanPurserMD · X

3. Kattoor, A. J., Pothineni, N. V., Palagiri, D., & Mehta, J. L. (2017). Oxidative Stress in Atherosclerosis. Current Atherosclerosis Reports, 19(11), 42. 4. Carr, A. C., & Maggini, S. (2017). Vitamin C and Immune Function. Nutrients, 9(11), 1211.

May 25, 2023 · 1,018 followers View post →
a!
@khhaieshaechan · X

@DrizzyhwJames say no more, what’s the role of oxidative stress in atherosclerosis please

Mar 9, 2023 · 305 followers View post →
INDoximity
@indoximity · X

Effects of fat loading on oxidative stress in atherosclerosis https://t.co/TGuFG9rCQp #GeneralSurgery

Jan 3, 2022 · 832 followers View post →
mR eYe is a nOneucLidIaN entity
@dvoicenyc · X

Vasculoprotective Role of Olive Oil Compounds via Modulation of Oxidative Stress in Atherosclerosis https://t.co/cGSWrEW077

Dec 29, 2021 · 96 followers View post →
12Alice Lee
@PepperPell · X

RT @glenpyle: NOXal action: #NOX1 links Endothelin-1 & pro-inflammatory #oxidative stress in #atherosclerosis. @AnastasiaSMihai @_atanas_…

Oct 24, 2020 · 5 shares · 3,162 followers View post →
International Natural Product Sciences Taskforce
@_INPST · X

RT @glenpyle: NOXal action: #NOX1 links Endothelin-1 & pro-inflammatory #oxidative stress in #atherosclerosis. @AnastasiaSMihai @_atanas_…

Oct 24, 2020 · 5 shares · 10,291 followers View post →
Sergey Minaev
@sminaev2015 · X

RT @glenpyle: NOXal action: #NOX1 links Endothelin-1 & pro-inflammatory #oxidative stress in #atherosclerosis. @AnastasiaSMihai @_atanas_…

Oct 24, 2020 · 5 shares · 31,505 followers View post →
Atanas G. Atanasov
@_atanas_ · X

RT @glenpyle: NOXal action: #NOX1 links Endothelin-1 & pro-inflammatory #oxidative stress in #atherosclerosis. @AnastasiaSMihai @_atanas_…

Oct 24, 2020 · 5 shares · 124,329 followers View post →
Dr Anastasia Mihailidou FAHA FCSANZ FESC
@AnastasiaSMihai · X

RT @glenpyle: NOXal action: #NOX1 links Endothelin-1 & pro-inflammatory #oxidative stress in #atherosclerosis. @AnastasiaSMihai @_atanas_…

Oct 23, 2020 · 5 shares · 19,390 followers View post →
Glen Pyle | #WomensHeartHealth ❤️‍
@glenpyle · X

NOXal action: #NOX1 links Endothelin-1 & pro-inflammatory #oxidative stress in #atherosclerosis. @AnastasiaSMihai @_atanas_ @KateyRayner @prof_brunt https://t.co/pIXA598lA0

Oct 23, 2020 · 19 likes · 5 shares · 7,243 followers View post →
MRX
@researchmrx · X

RT @naturalhealthbl: Vasculoprotective Role of Olive Oil Compounds via Modulation of Oxidative Stress in Atherosclerosis Source - https://…

Jun 13, 2020 · 1 share · 7,733 followers View post →
The Natural Health Blogger
@naturalhealthbl · X

Vasculoprotective Role of Olive Oil Compounds via Modulation of Oxidative Stress in Atherosclerosis Source - https://t.co/BCghSHPrYn https://t.co/vZHcUXue8X #OliveOil #MediterraneanDiet #Paleo #Vegan #Plantbased #Health #Science #HeartDisease https://t.co/8RHsTjawih

Jun 13, 2020 · 1 like · 1 share · 2,288 followers View post →
Iván
@Dockat16 · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Sep 5, 2019 · 25 shares · 87 followers View post →
Salesianos Argentina
@salesianoarg1 · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Sep 4, 2019 · 25 shares · 605 followers View post →
Rafael Valle -Oñate
@OnateValle · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Sep 3, 2019 · 25 shares · 481 followers View post →
Raul Villar
@DrRaulvillar · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Sep 2, 2019 · 25 shares · 411 followers View post →
Marufah Bolanle Alao
@bolarauf · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Sep 1, 2019 · 25 shares · 769 followers View post →
Hugo Rubalcava
@HugoRubalcava · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Sep 1, 2019 · 25 shares · 262 followers View post →
Germán Alirio Luna Chacón
@galunach · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 31, 2019 · 25 shares · 3,715 followers View post →
IANCARDIOLOGY
@CardioIAN · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 31, 2019 · 25 shares · 8,256 followers View post →
Arya KanJiyani
@Aryakanjiyani · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 29, 2019 · 25 shares · 1,287 followers View post →
Temi Diaz Strunz
@DiazStrunz · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 29, 2019 · 25 shares · 2,743 followers View post →
satish rath
@DrSatishRath · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 28, 2019 · 25 shares · 182 followers View post →
Arz Lubnan
@tallcedarofleb · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 27, 2019 · 25 shares · 2,789 followers View post →
Andrés A. Ponce M.D., Ph.D.
@aponce · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 24, 2019 · 25 shares · 1,578 followers View post →
Gregoire Millet
@GregoireMillet1 · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 18, 2019 · 25 shares · 5,780 followers View post →
07ARYA
@07MR_ARYA · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 17, 2019 · 25 shares · 1,177 followers View post →
EduardorubianoPhD.
@Hedurubiano · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 15, 2019 · 25 shares · 1,399 followers View post →
Erick Rosal
@ErickRosal1 · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 14, 2019 · 25 shares · 3 followers View post →
Lanzule, Inc.
@lanzule · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 14, 2019 · 25 shares · 1,053 followers View post →
Kevin Francis
@MrKevinFrancis · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 12, 2019 · 25 shares · 184 followers View post →
OJ
@jonathanotcher1 · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 10, 2019 · 25 shares · 2,147 followers View post →
PATRICIA JANSONS
@PATRICIAJANSONS · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 7, 2019 · 25 shares · 715 followers View post →
jose de la fuente
@Pipo666FC · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Aug 7, 2019 · 25 shares · 4,745 followers View post →
dr.rezashahanaghi
@DrShahanaghi · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Jun 25, 2019 · 25 shares · 330 followers View post →
Puma58
@sergioalej07 · X

RT @FrontiersIn: Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stre…

Jun 20, 2019 · 25 shares · 2,225 followers View post →
Frontiers
@FrontiersIn · X

Researchers discussed effects of mechanisms such as inflammation, mitochondria, autophagy or apoptosis on #oxidative #stress in #atherosclerosis, as well as possible treatments for #antioxidative stress. #openaccess review @FrontPhysiol; read & download: https://t.co/iNamYc7VFQ https://t.co/TdIlMmUb1U

Jun 19, 2019 · 70 likes · 25 shares · 90,067 followers View post →
Novus Biologicals, a Bio-Techne brand
@novusbio · X

New #Science Blog: New study connects atherosclerotic plaque buildup to leaky gut and #microbiome derived LPS, implicating TLR4-mediated oxidative stress in #atherosclerosis. Read More: https://t.co/GPBAl5aipZ https://t.co/jjbYSrV0xg

Mar 26, 2019 · 1 like · 3,113 followers View post →