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JCI Insight October 2017 PMID 28978809

Dietary potassium regulates vascular calcification and arterial stiffness.

Yong Sun, Chang Hyun Byon, Youfeng Yang, Wayne E Bradley, Louis J Dell'Italia, Paul W Sanders, Anupam Agarwal, Hui Wu, Yabing Chen

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Mentions

134
Peak: 8 in Jul 2025
across 6 sources since Oct 2017

Extended reach

451,570
potential audience

Total likes

5,296

Video views

146,487

Mentions per month

Oct 2017 – Nov 2025

Where it's discussed

  • News84 articles
  • X / Twitter24 posts
  • Facebook18 posts
  • Reddit3 posts
  • Blogs3 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions demonstrate strong agreement with the findings, as multiple posts emphasize the link between potassium and artery health, with some referencing molecular mechanisms like calcium signaling. Users exhibit high interest through mentions of specific research details and implications, though their engagement remains moderate. The tone is largely supportive and focused on health impact, suggesting the publication could influence dietary recommendations or medical approaches related to mineral intake and vascular health.

AgreementModerate agreement

Most discussions express support for the study’s findings, emphasizing the protective role of potassium against vascular calcification.

InterestHigh interest

The discussions show high interest, with users referencing specific parts of the research and its implications.

EngagementModerate engagement

Participants reference mechanisms and repeat key points, indicating moderate depth of engagement.

ImpactModerate impact

Multiple comments highlight the potential health implications, suggesting the study could influence dietary or medical practices.

Abstract in brief

  • Reduced dietary potassium intake is linked to increased vascular calcification and arterial stiffness, which are risk factors for cardiovascular diseases like hypertension and stroke.
  • The study using ApoE-deficient mice found that lower potassium levels (0.3) promote calcification and stiffness, while higher potassium levels (2.1) reduce these effects, and mechanisms involve increased calcium inside cells activating CREB and autophagy pathways.
  • Inhibiting calcium signaling, CREB, or autophagy-related proteins lessened calcification, suggesting that dietary potassium influences vascular health through these molecular pathways, offering potential targets for therapy.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Mani Malagón
@ManiMalagon · X

Sun Y, et al, Dietary potassium regulates vascular calcification and arterial stiffness. JCI Insight, 5.10.2017;2(19). pii: 94920. doi: 10.1172/jci.insight.94920. PMID: 28978809. @FatEmperor https://t.co/ccHrq1ts9y

Nov 12, 2019 · 15 likes · 6 shares · 447 followers View post →
Reiner 
@erlesen · X

Lower potassium levels in the blood, known as hypokalemia, are associated with an increased risk of arteriosclerosis (hardening of the arteries), and persistent potassium deficiency can contribute to calcification of the arteries https://t.co/PAZvnnhsJe

Jul 2, 2025 · 5 likes · 2 shares · 7,866 followers View post →
Cloward-Piven citizen
@paulojsvaz · X

@mike_lustgarten true. calcification is due to lack of potassium found in some green vegetables: https://t.co/65TLWoU7Hv

Jan 9, 2021 · 2 likes · 240 followers View post →
Tarun TejpaŁ
@TTejpal · X

This Mineral Deficiency is causing Calcified Arteries. https://t.co/jYZXwGmlBN via @YouTube

Jul 3, 2025 · 1 like · 1,758 followers View post →
JUAN ARIEL JARA GUER
@Tigerariel40 · X

Dietary potassium regulates vascular calcification and arterial stiffness https://t.co/ORljeM9wm0

Dec 21, 2020 · 1 like · 1 share · 156 followers View post →
Ivor Cummins
@FatEmperor · X

RT @ManiMalagon: Sun Y, et al, Dietary potassium regulates vascular calcification and arterial stiffness. JCI Insight, 5.10.2017;2(19). pii…

Nov 12, 2019 · 6 shares · 278,030 followers View post →

All mentions

Ash
@Jeff17503539993 · X

Dietary potassium regulates vascular calcification and arterial stiffness https://t.co/ZkM0HyKMhG

Nov 10, 2025 View post →
Fred Endow
@EndowFred · X

This Mineral Deficiency is causing Calcified Arteries. It is not vitamin k. https://t.co/w5Uwc0UarQ via @YouTube

Sep 4, 2025 · 303 followers View post →
Ray
@Sooorad · X

Potassium Mineral Deficiency is causing Calcified Arteries. https://t.co/MAkl2k9Mll via @YouTube

Aug 16, 2025 · 1,741 followers View post →
Reiner 
@erlesen · X

RT @erlesen: Lower potassium levels in the blood, known as hypokalemia, are associated with an increased risk of arteriosclerosis (hardenin…

Aug 10, 2025 · 2 shares · 7,866 followers View post →
Christof Meinhold
@nutri_cologne · X

RT @erlesen: Lower potassium levels in the blood, known as hypokalemia, are associated with an increased risk of arteriosclerosis (hardenin…

Jul 4, 2025 · 2 shares · 2,512 followers View post →
bioenergeticbot
@bioenergeticbot · X

Dietary potassium regulates vascular calcification and arterial stiffness https://t.co/1V7TKAb9G4 Literature Review || DavidPS

Jul 3, 2025 · 326 followers View post →
Tarun TejpaŁ
@TTejpal · X

This Mineral Deficiency is causing Calcified Arteries. https://t.co/jYZXwGmlBN via @YouTube

Jul 3, 2025 · 1 like · 1,758 followers View post →
Karageorgos
@Karageorgos15 · X

This Mineral Deficiency is causing Calcified Arteries. https://t.co/ZRoXfpq9Iy via @YouTube

Jul 2, 2025 · 611 followers View post →
Internet Jnani
@internet_jnani · X

This Mineral Deficiency is causing Calcified Arteries. https://t.co/yREap1dVQD via @YouTube

Jul 2, 2025 · 545 followers View post →
BookerDog
@MarcusKroppIII · X

This Mineral Deficiency is causing Calcified Arteries. https://t.co/FvL4gI6YLU via @YouTube

Jul 2, 2025 · 311 followers View post →
Reiner 
@erlesen · X

Lower potassium levels in the blood, known as hypokalemia, are associated with an increased risk of arteriosclerosis (hardening of the arteries), and persistent potassium deficiency can contribute to calcification of the arteries https://t.co/PAZvnnhsJe

Jul 2, 2025 · 5 likes · 2 shares · 7,866 followers View post →
Cloward-Piven citizen
@paulojsvaz · X

@mike_lustgarten true. calcification is due to lack of potassium found in some green vegetables: https://t.co/65TLWoU7Hv

Jan 9, 2021 · 2 likes · 240 followers View post →
JUAN ARIEL JARA GUER
@Tigerariel40 · X

RT @Tigerariel40: Dietary potassium regulates vascular calcification and arterial stiffness https://t.co/ORljeM9wm0

Dec 21, 2020 · 1 share · 156 followers View post →
JUAN ARIEL JARA GUER
@Tigerariel40 · X

Dietary potassium regulates vascular calcification and arterial stiffness https://t.co/ORljeM9wm0

Dec 21, 2020 · 1 like · 1 share · 156 followers View post →
JUAN ARIEL JARA GUER
@Tigerariel40 · X

Dietary potassium regulates vascular calcification and arterial stiffness https://t.co/ORljeM9wm0

Feb 3, 2020 · 156 followers View post →
JUAN ARIEL JARA GUER
@Tigerariel40 · X

Dietary potassium regulates vascular calcification and arterial stiffness https://t.co/ORljeM9wm0

Jan 25, 2020 · 156 followers View post →
Austin Jeans
@jeansdoc61 · X

RT @ManiMalagon: Sun Y, et al, Dietary potassium regulates vascular calcification and arterial stiffness. JCI Insight, 5.10.2017;2(19). pii…

Nov 13, 2019 · 6 shares · 963 followers View post →
Mike Knickerbocker
@MJKnickerbocker · X

RT @ManiMalagon: Sun Y, et al, Dietary potassium regulates vascular calcification and arterial stiffness. JCI Insight, 5.10.2017;2(19). pii…

Nov 12, 2019 · 6 shares · 285 followers View post →
Messner
@_messner · X

RT @ManiMalagon: Sun Y, et al, Dietary potassium regulates vascular calcification and arterial stiffness. JCI Insight, 5.10.2017;2(19). pii…

Nov 12, 2019 · 6 shares · 62 followers View post →
Hot Dog
@justin_mrjan4 · X

RT @ManiMalagon: Sun Y, et al, Dietary potassium regulates vascular calcification and arterial stiffness. JCI Insight, 5.10.2017;2(19). pii…

Nov 12, 2019 · 6 shares · 42 followers View post →
Sue
@Diamondkfarms · X

RT @ManiMalagon: Sun Y, et al, Dietary potassium regulates vascular calcification and arterial stiffness. JCI Insight, 5.10.2017;2(19). pii…

Nov 12, 2019 · 6 shares · 415 followers View post →
Ivor Cummins
@FatEmperor · X

RT @ManiMalagon: Sun Y, et al, Dietary potassium regulates vascular calcification and arterial stiffness. JCI Insight, 5.10.2017;2(19). pii…

Nov 12, 2019 · 6 shares · 278,030 followers View post →
Mani Malagón
@ManiMalagon · X

Sun Y, et al, Dietary potassium regulates vascular calcification and arterial stiffness. JCI Insight, 5.10.2017;2(19). pii: 94920. doi: 10.1172/jci.insight.94920. PMID: 28978809. @FatEmperor https://t.co/ccHrq1ts9y

Nov 12, 2019 · 15 likes · 6 shares · 447 followers View post →
Márcio Medeiros
@marcio3268medei · X

JCI Insight - Dietary potassium regulates vascular calcification and arterial stiffness https://t.co/DGg8zueDF4

Sep 16, 2019 · 36 followers View post →