Neurotherapeutics January 2018 PMID 29134359

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides.

Gilliard Lach, Harriet Schellekens, Timothy G Dinan, John F Cryan

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Mentions

57
Peak: 12 in Mar 2019
across 5 sources since Mar 2019

Extended reach

352,665
potential audience

Total likes

5,206

Video views

149,385

Mentions per month

Mar 2019 – Jan 2023

Where it's discussed

  • X / Twitter22 posts
  • News20 articles
  • Facebook6 posts
  • Blogs6 articles
  • YouTube3 videos

AI synopsis

What people are saying

Discussions highlight the role of gut peptides like NPY, oxytocin, and ghrelin, with mentions of how diet and microbiota impact mental health, indicating a genuine interest and moderate engagement. The tone suggests the community perceives this research as meaningful but not revolutionary, emphasizing its potential influence on understanding and managing mental health issues.

AgreementModerate agreement

Most posts reflect a general consensus that the article presents valid and important insights into the relationship between the microbiome and mental health, with some posts citing the significance of gut peptides in mood regulation.

InterestModerate interest

Posts demonstrate moderate curiosity, mentioning specific hormones and mechanisms, but mostly focus on general concepts rather than deep scientific details.

EngagementModerate engagement

Several discussions reference relevant biological processes and potential applications, indicating a moderate level of engagement with the research’s implications.

ImpactModerate impact

Comments suggest that the research could influence future mental health treatments and lifestyle recommendations, recognizing its potential significance.

Abstract in brief

  • The text explains the complex communication system between the gut and brain, involving multiple bodily systems, and highlights the emerging role of the microbiome and its molecules in regulating this interaction, particularly through gut peptides.
  • It emphasizes that gut-derived peptides, which are hormones secreted by the gastrointestinal tract, can influence brain function and mood by interacting with immune cells and nerve pathways, and their levels are affected by microbiota composition.
  • The review explores how the microbiome may regulate anxiety and depression through these gut peptides and discusses specific hormones like neuropeptide Y, oxytocin, and ghrelin as key signaling molecules in gut-brain communication.]

Top posts

Most liked on X and Bluesky
GutMicrobiota Health
@GMFHx · X

The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also important regulators of microbiota-gut-brain signaling in health and stress-related psychiatric illnesses, suggests this review https://t.co/sgjNgfoUpj

Mar 21, 2019 · 29 likes · 14 shares · 35,498 followers View post →
Nick Norwitz MD PhD
@nicknorwitz · X

Fact of day 162: Amygdala (almond-shaped structure in the brain responsible for fight-or-flight response / anger / anxiety) has receptors for gut signaling molecules like NPY, PP, and GLP-1. What you eat matters for mental health. #anxiety #GutBrainAxis https://t.co/cE2V0YLqPR

Jul 28, 2020 · 15 likes · 2 shares · 108,758 followers View post →
4QuorumSensing
@4QuorumSensing · X

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides https://t.co/sSXjwpCaCE

May 9, 2020 · 2 likes · 6,382 followers View post →
Lee Stevenson
@bashuser · X

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides https://t.co/gkWWTj578H

Jul 27, 2022 · 2 likes · 1,702 followers View post →
Lee Stevenson
@bashuser · X

This is why people are mentally ill. They have people so paranoid of germs they are killing their gut microbes off. Germs are not the enemy. https://t.co/dBR98WJy8Q

Jan 23, 2023 · 2 likes · 1,702 followers View post →
Dr. Anne Estes @mostlymicrobes.bsky.social
@MostlyMicrobes · X

@ReadMoreScience Exercise and healthier food (more fruits and veggies) help out those gut microbes that make the dopamine and serotonin, so.... @jfcryan has a great book connecting gut microbes and mental health: https://t.co/m9UrSsnflx. Here's review article: https://t.co/788q71iW4C

Dec 29, 2020 · 1 like · 3,081 followers View post →

All mentions

Physical Symptoms of Anxiety and Their Impact

Anxiety produces physical symptoms such as insomnia, fatigue, and muscle tension, which are often easier to identify than mental symptoms. This video explores these symptoms and emphasizes the importance of addressing…

Psych2Go · May 5, 2022 148,277 views
Lee Stevenson
@bashuser · X

This is why people are mentally ill. They have people so paranoid of germs they are killing their gut microbes off. Germs are not the enemy. https://t.co/dBR98WJy8Q

Jan 23, 2023 · 2 likes · 1,702 followers View post →
Lee Stevenson
@bashuser · X

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides https://t.co/gkWWTj578H

Jul 27, 2022 · 2 likes · 1,702 followers View post →
CHANG LIJIA
@CHANGLIJIA9595 · X

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides https://t.co/JS5TCiwQaC https://t.co/vFvnOUxZZc

Nov 4, 2021 · 34 followers View post →
Dr. Anne Estes @mostlymicrobes.bsky.social
@MostlyMicrobes · X

@ReadMoreScience Exercise and healthier food (more fruits and veggies) help out those gut microbes that make the dopamine and serotonin, so.... @jfcryan has a great book connecting gut microbes and mental health: https://t.co/m9UrSsnflx. Here's review article: https://t.co/788q71iW4C

Dec 29, 2020 · 1 like · 3,081 followers View post →
Lisa Thomas
@lisamjthomas · X

RT @nicknorwitz: Fact of day 162: Amygdala (almond-shaped structure in the brain responsible for fight-or-flight response / anger / anxiety…

Jul 29, 2020 · 2 shares · 187 followers View post →
(D) (R) (I) Distancing
@StephaniePalosP · X

RT @nicknorwitz: Fact of day 162: Amygdala (almond-shaped structure in the brain responsible for fight-or-flight response / anger / anxiety…

Jul 28, 2020 · 2 shares · 3,196 followers View post →
Nick Norwitz MD PhD
@nicknorwitz · X

Fact of day 162: Amygdala (almond-shaped structure in the brain responsible for fight-or-flight response / anger / anxiety) has receptors for gut signaling molecules like NPY, PP, and GLP-1. What you eat matters for mental health. #anxiety #GutBrainAxis https://t.co/cE2V0YLqPR

Jul 28, 2020 · 15 likes · 2 shares · 108,758 followers View post →
4QuorumSensing
@4QuorumSensing · X

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides https://t.co/sSXjwpCaCE

May 9, 2020 · 2 likes · 6,382 followers View post →
DrRPalmquist
@DrPalmquist · X

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides - PubMed https://t.co/PKKM01yUnZ

Apr 3, 2020 · 3,158 followers View post →
Dr Richard Palmquist
@DrRPalmquist · X

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides. - PubMed - NCBI https://t.co/DftIsPDDwy

May 6, 2019 · 4,728 followers View post →
lee stein
@leestein · X

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides | SpringerLink https://t.co/wfSCiXDubX

Mar 22, 2019 · 338 followers View post →
Emad El-Omar
@emadelomar · X

RT @GMFHx: The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also im…

Mar 21, 2019 · 14 shares · 3,877 followers View post →
Rebecca Costa
@rebeccacosta · X

RT @GMFHx: The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also im…

Mar 21, 2019 · 14 shares · 13,766 followers View post →
Saubashya Sur, PhD
@SaubashyaSur · X

RT @GMFHx: The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also im…

Mar 21, 2019 · 14 shares · 768 followers View post →
Анатолій АНЧИШКІН
@deltakr · X

RT @GMFHx: The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also im…

Mar 21, 2019 · 14 shares · 403 followers View post →
Bente Brunvoll
@BenteBrunvoll · X

RT @GMFHx: The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also im…

Mar 21, 2019 · 14 shares · 195 followers View post →
Digestive Nutrition Clinic
@digestivenc · X

RT @GMFHx: The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also im…

Mar 21, 2019 · 14 shares · 374 followers View post →
Noemi Cuenca (Dietista-Nutricionista)
@noemicuencaq · X

RT @GMFHx: The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also im…

Mar 21, 2019 · 14 shares · 539 followers View post →
Herman Scholtz
@hscholtz · X

RT @GMFHx: The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also im…

Mar 21, 2019 · 14 shares · 2,522 followers View post →
htw
@heniek_htw · X

RT @GMFHx: The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also im…

Mar 21, 2019 · 14 shares · 11,263 followers View post →
GutMicrobiota Health
@GMFHx · X

The endocrine, immune & enteric nervous systems dictate how gut microbiota talks to the brain. Further, gut peptides are also important regulators of microbiota-gut-brain signaling in health and stress-related psychiatric illnesses, suggests this review https://t.co/sgjNgfoUpj

Mar 21, 2019 · 29 likes · 14 shares · 35,498 followers View post →
GutMicrobiomePapers
@GutPapers · X

Anxiety, Depression, and the Microbiome: A Role for Gut Peptides. https://t.co/PRDTOwm55Y

Mar 14, 2019 · 1 like · 518 followers View post →