Nature November 2017 PMID 29143823

Salt-responsive gut commensal modulates T17 axis and disease.

Nicola Wilck, Mariana G Matus, Sean M Kearney, Scott W Olesen, Kristoffer Forslund, Hendrik Bartolomaeus, Stefanie Haase, Anja Mähler, András Balogh, Lajos Markó, Olga Vvedenskaya, Friedrich H Kleiner, Dmitry Tsvetkov, Lars Klug, Paul I Costea

Mentions

48
Peak: 15 in Nov 2017
across 7 sources since Nov 2017

Extended reach

18,330
potential audience

Total likes

35

Video views

1,818

Mentions per month

Nov 2017 – Aug 2025

Where it's discussed

  • News22 articles
  • Blogs11 articles
  • Facebook6 posts
  • X / Twitter4 posts
  • YouTube2 videos
  • Instagram2 posts
  • Reddit1 posts

AI synopsis

What people are saying

The overall tone reflects agreement with the article, as posts frequently mention how high salt intake depletes beneficial gut bacteria such as Lactobacillus murinus, and underscore its role in immune regulation and disease prevention. Words like 'confirms,' 'benefits,' and 'supports' show a supportive attitude, while references to previous research reinforce the idea that these findings are part of an important ongoing scientific conversation.

AgreementStrong agreement

Most discussions strongly support the findings, emphasizing that high salt intake negatively impacts beneficial gut bacteria and immune regulation.

InterestModerate interest

Participants show moderate interest, with some posts highlighting the significance of the research without delving too deeply into technical details.

EngagementModerate engagement

Posts demonstrate some engagement through mentions of scientific results, like the depletion of Lactobacillus murinus and its link to health issues.

ImpactModerate impact

The discussions suggest that the findings are relevant and could influence ongoing research and dietary considerations, making it moderately impactful.

Abstract in brief

  • High salt consumption can harm gut bacteria, especially reducing Lactobacillus murinus, which is important in immune regulation and disease development.
  • Supplementing with Lactobacillus murinus in mice helps prevent salt-related increases in T helper 17 (T17) cells, autoimmune diseases, and high blood pressure.
  • A human pilot study suggests that even moderate high salt intake can decrease beneficial gut bacteria, boost T17 cells, and raise blood pressure, highlighting the gut microbiome's role in salt-related health issues.]

Top posts

Most liked on X and Bluesky
Reijo Laatikainen
@Reijo_RD_FIN · X

Tutkimus vahvistaa parin viime vuoden aikaisia tutkimustuloksia. Liika suolan saanti ei tee hyvää suolistomikrobeille, ja vähäsuolainen on suolistobakteereille eduksi https://t.co/bLDwC1lSIs

Jul 29, 2020 · 4 likes · 4,608 followers View post →
豆乳ヨーグルトのプロバイオ
@Probio_ASO · X

塩分摂取と腸内細菌について https://t.co/x2ycGeCwbX マウス試験での報告。 塩分を多く摂取したマウスでは、便中で一部の乳酸菌の減少が確認

Dec 12, 2021 · 2 likes · 174 followers View post →
UltimApe
@ultimape · X

"Induction of TH17 cells depends on gut microbiota; however, the effect of salt on the gut microbiome is unknown. Here we show that high salt intake affects the gut microbiome in mice, particularly by depleting Lactobacillus murinus." [2017] https://t.co/onJzGoJvJq

Dec 13, 2021 · 6,741 followers View post →
とうや@食品メーカー研究職
@NzXyZQDOCMpLgz5 · X

食塩で思い出すのが、2017年のNatureの論文。食塩負荷により腸内の乳酸菌が減り、Th17に起因する疾患や血圧上昇につながるという内容。 この論文は動物とドイツ人が対象ですが、食塩摂取が多い日本人ではどうなのか凄く気になったことを覚えています。 https://t.co/Tka6gjngbu https://t.co/PwpAEW6Ymj

Jul 20, 2022 · 4,569 followers View post →

All mentions

Impact of Salt on Gut Microbiota and Immune Regulation

High salt intake can negatively affect gut bacteria like Lactobacillus murinus, influencing immune responses and disease risk. Supplementing with beneficial bacteria may mitigate these effects and improve health.

Guna · Nov 18, 2024 162 views
とうや@食品メーカー研究職
@NzXyZQDOCMpLgz5 · X

食塩で思い出すのが、2017年のNatureの論文。食塩負荷により腸内の乳酸菌が減り、Th17に起因する疾患や血圧上昇につながるという内容。 この論文は動物とドイツ人が対象ですが、食塩摂取が多い日本人ではどうなのか凄く気になったことを覚えています。 https://t.co/Tka6gjngbu https://t.co/PwpAEW6Ymj

Jul 20, 2022 · 4,569 followers View post →
UltimApe
@ultimape · X

"Induction of TH17 cells depends on gut microbiota; however, the effect of salt on the gut microbiome is unknown. Here we show that high salt intake affects the gut microbiome in mice, particularly by depleting Lactobacillus murinus." [2017] https://t.co/onJzGoJvJq

Dec 13, 2021 · 6,741 followers View post →
豆乳ヨーグルトのプロバイオ
@Probio_ASO · X

塩分摂取と腸内細菌について https://t.co/x2ycGeCwbX マウス試験での報告。 塩分を多く摂取したマウスでは、便中で一部の乳酸菌の減少が確認

Dec 12, 2021 · 2 likes · 174 followers View post →
Reijo Laatikainen
@Reijo_RD_FIN · X

Tutkimus vahvistaa parin viime vuoden aikaisia tutkimustuloksia. Liika suolan saanti ei tee hyvää suolistomikrobeille, ja vähäsuolainen on suolistobakteereille eduksi https://t.co/bLDwC1lSIs

Jul 29, 2020 · 4 likes · 4,608 followers View post →
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Dr Ábner Paz, Prof. RD,MSc-Nutri.Oncológico | Manaus AM
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Fontes: doi: 10.1038 / nature24628. doi: 10.1161 / HYPERTENSIONAHA.120.14800. doi: 10.1038 / nature11868. ⠀ #microbiotaintestinal #microbioma #sódio #sal ...

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Wilck N, et al. Salt-responsive gut commensal modulates T(H)17 axis and disease. Nature. 2017;551(7682):585–589. doi:10.1038/nature24628

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