November 2017 PMID 29180820

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis.

Katarina Ondrusova, Mohammad Fatehi, Amy Barr, Zofia Czarnecka, Wentong Long, Kunimasa Suzuki, Scott Campbell, Koenraad Philippaert, Matthew Hubert, Edward Tredget, Peter Kwan, Nicolas Touret, Martin Wabitsch, Kevin Y Lee, Peter E Light

Download social card

Mentions

26
Peak: 4 in Jan 2018
across 5 sources since Jan 2018

Extended reach

494,308
potential audience

Total likes

82

Video views

2,210

Mentions per month

Jan 2018 – Sep 2025

Where it's discussed

  • X / Twitter13 posts
  • News9 articles
  • YouTube2 videos
  • Facebook1 posts
  • Instagram1 posts

AI synopsis

What people are saying

The discussions demonstrate a general agreement on the importance of the light-sensitive pathways in fat cells, with posts referencing related concepts like circadian rhythms, hormones such as leptin, and potential applications in controlling hunger. The tone varies from curiosity to cautious optimism, with mentions of related biological processes reinforcing the perceived significance of the research.

AgreementModerate agreement

Most discussions seem to accept the significance of light-sensitive pathways in white fat cells and their potential implications, reflecting cautious agreement.

InterestModerate interest

Participants show moderate interest, as they connect the research to broader topics like metabolism, hunger regulation, and seasonal biology.

EngagementNeutral engagement

While some posts reference specific mechanisms and suggest applications, the overall depth of discussion remains superficial, indicating a moderate level of engagement.

ImpactModerate impact

The discussions imply that this research could influence future approaches to weight management and metabolic health, but do not suggest an immediate revolutionary impact.

Abstract in brief

  • Subcutaneous white adipose tissue (scWAT) is a key fat storage area in humans and plays a vital role in overall metabolism.
  • Researchers discovered that blue light, which penetrates the skin, activates a specific pathway in scWAT through melanopsin and certain ion channels.
  • Exposure to blue light led to reduced fat droplet size, increased fat breakdown, and changes in the secretion of hormones related to fat metabolism, suggesting that sunlight exposure can significantly influence scWAT function.

Top posts

Most liked on X and Bluesky
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

@BodyRecompExprt Repairing melanopsin should be number one first approach here. https://t.co/UBj6pF2a2t But those dietary additions may also be useful here. Just not sure what your diet already consists of currently to know for sure.

Nov 14, 2024 · 13 likes · 133,607 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis https://t.co/Zc54w6mdzB https://t.co/JxLBMZ4sck

Jan 5, 2022 · 11 likes · 2 shares · 133,607 followers View post →
MontgomeryMD
@sjacobm321 · X

@drnickgreiner @Mangan150 To control hunger one has to control Leptin & Ghrelin the energy and hunger hormones. Leptin produced by SQ fat cells, Ghrelin in the stomach. And believe it or not, they are most influenced by light.

Dec 7, 2020 · 11 likes · 2 shares · 25,494 followers View post →
Iodine
@Photo2Electric · X

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis https://t.co/LNIaRKDvZ9

May 31, 2024 · 3 likes · 3,870 followers View post →
John Beach
@JohnBeachTX · X

@KirkMMaxey Closing the PubMed browser, I thought "hmmm, blue light, circadian, lipid, cryptochrome..." For fun, I searched leptin "blue light" This certainly sounds relevant to seasonal biology https://t.co/M4aiR6P0h7 Adipose tissue, light sensing, lipid, secretion of leptin, adiponectin

Jul 14, 2021 · 1 like · 475 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

RT @Grimhood: Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis https:/…

Apr 20, 2022 · 1 share · 133,607 followers View post →

All mentions

Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

@BodyRecompExprt Repairing melanopsin should be number one first approach here. https://t.co/UBj6pF2a2t But those dietary additions may also be useful here. Just not sure what your diet already consists of currently to know for sure.

Nov 14, 2024 · 13 likes · 133,607 followers View post →
Iodine
@Photo2Electric · X

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis https://t.co/LNIaRKDvZ9

May 31, 2024 · 3 likes · 3,870 followers View post →
Agingdoc
@agingdoc1 · X

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis

Feb 12, 2024 · 42,594 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

RT @Grimhood: Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis https:/…

Apr 20, 2022 · 1 share · 133,607 followers View post →
Institue of Applied Quantum Biology
@IAQB_Foundation · X

@Chandle74418127 @sjacobm321 Or this… “Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis” https://t.co/Aj8ErLyOLk

Mar 16, 2022 · 9,557 followers View post →
plantbhai - 3bdu Al-Hakim
@HakimBGZ · X

RT @Grimhood: Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis https:/…

Jan 6, 2022 · 2 shares · 2,807 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis https://t.co/Zc54w6mdzB https://t.co/JxLBMZ4sck

Jan 5, 2022 · 11 likes · 2 shares · 133,607 followers View post →
John Beach
@JohnBeachTX · X

@KirkMMaxey Closing the PubMed browser, I thought "hmmm, blue light, circadian, lipid, cryptochrome..." For fun, I searched leptin "blue light" This certainly sounds relevant to seasonal biology https://t.co/M4aiR6P0h7 Adipose tissue, light sensing, lipid, secretion of leptin, adiponectin

Jul 14, 2021 · 1 like · 475 followers View post →
ENDALA klinika zdraví
@endalaclinic · X

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis | Scientific Reports https://t.co/Y47jDPtRQr

Mar 1, 2021 · 251 followers View post →
ENDALA klinika zdraví
@endalaclinic · X

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis | Scientific Reports https://t.co/Y47jDPcgrR

Feb 5, 2021 · 251 followers View post →
ENDALA klinika zdraví
@endalaclinic · X

Subcutaneous white adipocytes express a light sensitive signaling pathway mediated via a melanopsin/TRPC channel axis https://t.co/1z8mTuyG7u

Jan 17, 2021 · 251 followers View post →
Michael Padula HPA.Coach
@MJPadula · X

RT @sjacobm321: @drnickgreiner @Mangan150 To control hunger one has to control Leptin & Ghrelin the energy and hunger hormones. Leptin prod…

Dec 7, 2020 · 2 shares · 5,600 followers View post →
MontgomeryMD
@sjacobm321 · X

@drnickgreiner @Mangan150 To control hunger one has to control Leptin & Ghrelin the energy and hunger hormones. Leptin produced by SQ fat cells, Ghrelin in the stomach. And believe it or not, they are most influenced by light.

Dec 7, 2020 · 11 likes · 2 shares · 25,494 followers View post →
Alien Diet
Facebook

... 10.1038/s41598-017-16689-4 •Moderate Exercise and Bright Light Treatment in Overweight and Obese Individuals https://doi.org/10.1038/oby.2007.208 •Timing ...

Dec 13, 2025 View →
From Sick To Superhuman | PDF | Digestion | Biology
News

https://doi.org/10.1038/s41598- 017-16689-4. www.bioptimizers.com / 176. Biological Optimizer #7: Heliotherapy. deficiency is still epidemic. Over a billion ...

Dec 13, 2025 View →
Ritual Daily Practices For Wellness, Beauty Bliss (Vasudha Rai ...
News

https://doi.org/10.1038/s41598-017-16689-4. Randler, Christoph. 'Defend Your Research: The Early Bird Really Does Get the Worm'. Harvard Business Review ...

Dec 13, 2025 View →
Peter Light, University of Alberta [IMAGE] | EurekAlert! Science News ...
News

10.1038/s41598-017-16689-4. Keywords. /Life sciences/Cell biology/Cells/Adipocytes; /Life sciences/Cell biology/Cells/Skin cells; /Physical sciences/Physics ...

Dec 13, 2025 View →
What Happens to Your Body When You Get Sunlight Every Day
News

doi:10.1038/s41598-017-16689-4. U.S. Environmental Protection Agency. Sun safety tips. American Skin Association. Sun Safety. Hazell G ...

Sep 12, 2025 View →
Fat loss isn't just about diet and exercise. In fact, sunlight may play a ...
Instagram

473 likes, 9 comments - ra_optics on March 11, 2025: "Fat loss isn't just about diet and exercise. In fact, sunlight may play a bigger role ...

Mar 11, 2025 View →
今年过年你胖了么?为什么胖、如何减肥?最新研究快戳这里!
News

DOI: 10.1038/s41598-017-16689-4. 一项由阿尔伯塔大学研究人员进行的突破性研究发现我们的皮下脂肪组织会在太阳发出的蓝光作用下变小。 “当蓝光穿透 ...

Feb 23, 2018 View →
看文献的另类好处,有助减肥啊
News

... 10.1038/s41598-017-16689-4). 2.Locally Induced Adipose Tissue Browning by Microneedle Patch for Obesity Treatment.(DOI: 10.1021/acsnano ...

Jan 17, 2018 View →
Blaues Licht lässt Fettzellen schrumpfen - Trägt der winterliche ...
News

... 10.1038/s41598-017-16689-4). (University of Alberta, 12.01.2018 – NPO). 12. Januar 2018. Keine Meldungen mehr verpassen – mit unserem ...

Jan 12, 2018 View →
New discovery may explain winter weight gain | ScienceDaily
News

Scientific Reports, 2017; 7 (1) DOI: 10.1038/s41598-017-16689-4. Cite This Page: MLA; APA; Chicago. University of Alberta Faculty of Medicine ...

Jan 10, 2018 View →
New discovery may explain winter weight gain | EurekAlert!
News

10.1038/s41598-017-16689-4. Keywords. /Life sciences/Cell biology/Cells/Adipocytes; /Life sciences/Cell biology/Cells/Skin cells; /Physical ...

Jan 10, 2018 View →