The overall discussions show a strong interest with references to recent reviews, diagnosis tools, and management strategies, such as NEJM articles and diagnostic algorithms, indicating deep engagement. Words like 'delighted,' 'please elaborate,' and 'urgent topic' demonstrate active involvement and perceived significance of the condition's treatment and understanding.
AgreementModerate agreement
Most discussions support current knowledge and acknowledge the severity of NSTIs, showing general consensus on their seriousness and management.
InterestHigh interest
Posts demonstrate high curiosity, referencing multiple studies, reviews, and ongoing research, indicating active engagement with the topic.
EngagementModerate engagement
Participants elaborate on diagnosis, management, and new developments, reflecting moderate to deep involvement in the subject matter.
ImpactModerate impact
Discussions highlight the significant clinical impact of NSTIs, emphasizing the importance of research, guidelines, and global efforts to improve outcomes.
Abstract in brief
NSTIs are severe bacterial infections that rapidly destroy the skin, muscles, and other soft tissues, often requiring urgent medical intervention.
They are caused by various bacteria, including Group A Streptococcus, and present with symptoms like severe pain, swelling, fever, and tissue death.
Treatment typically involves emergency surgery to remove dead tissue and broad-spectrum antibiotics to fight the infection.]
Evolution of necrotizing fasciitis or myonecrosis
⭐ Around 50% of cases caused by group A streptococcus occurs without a portal of entry, often initiates deep in the soft tissues at sites of nonpenetrating trauma (e.g. muscle strain or bruise)
https://t.co/RVLj6i4bnm https://t.co/bmeebyusNh
@drkeithsiau Carbon monoxide poisoning is the most well-known indication.
Others include:
• Arterial gas embolism
• Decompression sickness
• Necrotizing soft-tissue infections
• Crush injuries & compartment syndrome
• Severe anemia when transfusion isn’t possible
• Radiation-induced
Nov 19, 2025 · 159 likes · 21 shares · 1,880 followersView post →
JN
Juan Pablo Sánchez Navarro
@melarsoprol7 · X
Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://t.co/AVYxpUKbce https://t.co/kihZ3Do4B6
Oct 24, 2025 · 134 likes · 41 shares · 1,418 followersView post →
亀亀
亀田 総合内科(亀田総合病院)
@kameda_gim · X
【壊死性筋膜炎】
診断におけるピットフォール
May 20, 2023 · 117 likes · 11 shares · 12,434 followersView post →
This video provides a basic educational overview of necrotizing fasciitis. It discusses the rapid progression of severe bacterial infections that destroy soft tissues, highlighting symptoms, causes, and the importance…
Necrotizing fasciitis is a severe infection causing rapid soft tissue destruction. Early diagnosis and urgent surgical debridement combined with broad-spectrum antibiotics are essential for effective management.
RT @DocPriyamMD: @drkeithsiau Carbon monoxide poisoning is the most well-known indication.
Others include:
• Arterial gas embolism
• Decomp…
Nov 20, 2025 · 21 shares · 113 followersView post →
I
InaIna
@Quer_coca_Ina · X
RT @DocPriyamMD: @drkeithsiau Carbon monoxide poisoning is the most well-known indication.
Others include:
• Arterial gas embolism
• Decomp…
Nov 20, 2025 · 21 shares · 207 followersView post →
AM
Abdurrahman Musa
@ttheabdurrahman · X
RT @DocPriyamMD: @drkeithsiau Carbon monoxide poisoning is the most well-known indication.
Others include:
• Arterial gas embolism
• Decomp…
Nov 20, 2025 · 21 shares · 245 followersView post →
E
esanum
@esanum · X
@drkeithsiau
Nov 20, 2025 · 1 like · 6,938 followersView post →
SM
Springer Medicine
@Springer_Med · X
While the principles of management are widely agreed upon, antibiotic therapies of necrotizing soft tissue infections remain heterogeneous.
Explore practical recommendations for empirical #antibiotic therapy with this review from @Crit_Care.
While the principles of management are widely agreed upon, #antibiotic therapies of necrotizing soft tissue infections remain heterogeneous.
This review explores practical recommendations for empirical antibiotic therapy.
@drkeithsiau Carbon monoxide poisoning is the most well-known indication.
Others include:
• Arterial gas embolism
• Decompression sickness
• Necrotizing soft-tissue infections
• Crush injuries & compartment syndrome
• Severe anemia when transfusion isn’t possible
• Radiation-induced
Nov 19, 2025 · 159 likes · 21 shares · 1,880 followersView post →
DY
Dieter Morales #yosoydelclinico
@RNCsantander · X
RT @estesonline: ESTES is delighted to invite all Members to join our upcoming study on Necrotizing Soft Tissue Infections SnapNSTI. Any qu…
Nov 16, 2025 · 5 shares · 3,467 followersView post →
AF
Andreu Martínez, MD, FACS
@andreumartinezh · X
RT @estesonline: ESTES is delighted to invite all Members to join our upcoming study on Necrotizing Soft Tissue Infections SnapNSTI. Any qu…
Nov 16, 2025 · 5 shares · 303 followersView post →
O
Olga
@olgarutka · X
RT @estesonline: ESTES is delighted to invite all Members to join our upcoming study on Necrotizing Soft Tissue Infections SnapNSTI. Any qu…
Nov 16, 2025 · 5 shares · 126 followersView post →
ES
European Society for Trauma & Emergency Surgery
@estesonline · X
ESTES is delighted to invite all Members to join our upcoming study on Necrotizing Soft Tissue Infections SnapNSTI. Any questions? Email snapnsti@gmail.com Twitter/X: @SnapNSTI
Necrotizing soft-tissue infection remains one of the most lethal emergencies we face in Europe. https://t.co/kBlCfrnjcZ
Nov 15, 2025 · 12 likes · 5 shares · 2,089 followersView post →
MA
Mohammed Alabdulla
@Mohamme72157286 · X
RT @melarsoprol7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
htt…
Oct 29, 2025 · 41 shares · 533 followersView post →
MA
Mohammed Mar'ae Asiri
@Asiritrauma1 · X
RT @JTraumAcuteSurg: Current diagnosis and management of necrotizing soft tissue infections: What you need to know https://t.co/q3x0QCM4QA
Oct 28, 2025 · 5 shares · 18,509 followersView post →
MM
Mr. Monei Makgasa Moneimang
@MMakgasa · X
RT @JTraumAcuteSurg: Current diagnosis and management of necrotizing soft tissue infections: What you need to know https://t.co/q3x0QCM4QA
Oct 28, 2025 · 5 shares · 589 followersView post →
AL
Aitor Landaluce
@LandaluceAitor · X
RT @JTraumAcuteSurg: Current diagnosis and management of necrotizing soft tissue infections: What you need to know https://t.co/q3x0QCM4QA
Oct 28, 2025 · 5 shares · 2,029 followersView post →
AY
Ali Cihat Yildirim
@dralicihat · X
RT @JTraumAcuteSurg: Current diagnosis and management of necrotizing soft tissue infections: What you need to know https://t.co/q3x0QCM4QA
Oct 28, 2025 · 5 shares · 1,644 followersView post →
JS
Journal of Trauma and Acute Care Surgery
@JTraumAcuteSurg · X
Current diagnosis and management of necrotizing soft tissue infections: What you need to know https://t.co/q3x0QCM4QA
Oct 28, 2025 · 25 likes · 5 shares · 28,466 followersView post →
M
Mariem.
@mariempf · X
RT @melarsoprol7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
htt…
Oct 27, 2025 · 41 shares · 352 followersView post →
MC
Ma.Semiglia Chong
@AuxiSemiglia · X
RT @melarsoprol7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
htt…
Oct 26, 2025 · 41 shares · 217 followersView post →
DP
Dr.SGanta@PharmD
@SaiduluGanta · X
RT @melarsoprol7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
htt…
Oct 26, 2025 · 41 shares · 770 followersView post →
CA
Climate, Ecology, War & More - Dr Glen Barry BigEarthData.ai
@bigearthdata.bsky.social · Bluesky
Study Identifies Rare Necrotizing Soft Tissue Infections Linked to Peripheral Venous Catheters in Pediatric Patients
->Gene Online | More from Lil Dr Glen EcoChat at BigEarthData.ai
RT @melarsoprol7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
htt…
Oct 24, 2025 · 41 shares · 133 followersView post →
B
Breadcrumbs
@Breadcr17527025 · X
RT @melarsoprol7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
htt…
Oct 24, 2025 · 41 shares · 90 followersView post →
H
heiderespinel
@heiderespinel · X
RT @melarsoprol7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
htt…
Oct 24, 2025 · 41 shares · 427 followersView post →
GR
Gonzalo Rivera
@AcinetoRiver · X
RT @melarsoprol7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
htt…
Oct 24, 2025 · 41 shares · 485 followersView post →
BA
Belén Atiencia
@Bel_atiencia · X
RT @melarsoprol7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
htt…
Oct 24, 2025 · 41 shares · 282 followersView post →
M
MR
@Maryam158158 · X
RT @melarsoprol7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
htt…
Oct 24, 2025 · 41 shares · 32 followersView post →
JN
Juan Pablo Sánchez Navarro
@melarsoprol7 · X
Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://t.co/AVYxpUKbce https://t.co/kihZ3Do4B6
Oct 24, 2025 · 134 likes · 41 shares · 1,418 followersView post →
A
Almansour
@malmansour81 · X
RT @ISICEM: @ISICEM Criticale Care Input
#Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Pari…
Oct 24, 2025 · 4 shares · 213 followersView post →
AS
Adarsh Srivastava
@AKSMDCCM · X
RT @ISICEM: @ISICEM Criticale Care Input
#Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Pari…
Oct 23, 2025 · 4 shares · 253 followersView post →
I
Iván
@IvanLimaL · X
RT @ISICEM: @ISICEM Criticale Care Input
#Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Pari…
Oct 23, 2025 · 4 shares · 175 followersView post →
I
ISICEM
@ISICEM · X
@ISICEM Criticale Care Input
#Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris #SURFAST consortium
Oct 23, 2025 · 10 likes · 4 shares · 10,984 followersView post →
CV
Cristina Rey Valcarcel
@DraReyValcarcel · X
RT @AMGC_Surg: Join the Global Effort to Improve Outcomes in Necrotizing Soft Tissue Infections with the SnapNSTI
Be part of an internatio…
Oct 20, 2025 · 8 shares · 206 followersView post →
A
ASGBI
@asgbi · X
RT @AMGC_Surg: Join the Global Effort to Improve Outcomes in Necrotizing Soft Tissue Infections with the SnapNSTI
Be part of an internatio…
Oct 20, 2025 · 8 shares · 17,013 followersView post →
O
Olga
@olgarutka · X
RT @AMGC_Surg: Join the Global Effort to Improve Outcomes in Necrotizing Soft Tissue Infections with the SnapNSTI
Be part of an internatio…
Oct 19, 2025 · 8 shares · 126 followersView post →
A
aecirujanos
@aecirujanos · X
RT @AMGC_Surg: Join the Global Effort to Improve Outcomes in Necrotizing Soft Tissue Infections with the SnapNSTI
Be part of an internatio…
Oct 19, 2025 · 8 shares · 12,812 followersView post →
CM
Christian Macutkiewicz
@SurgeryHPB · X
RT @AMGC_Surg: Join the Global Effort to Improve Outcomes in Necrotizing Soft Tissue Infections with the SnapNSTI
Be part of an internatio…
Oct 19, 2025 · 8 shares · 4,767 followersView post →
IP
Ines Rubio-Perez, PhD
@InesRPsurg · X
RT @AMGC_Surg: Join the Global Effort to Improve Outcomes in Necrotizing Soft Tissue Infections with the SnapNSTI
Be part of an internatio…
Oct 18, 2025 · 8 shares · 2,206 followersView post →
DY
Dieter Morales #yosoydelclinico
@RNCsantander · X
RT @AMGC_Surg: Join the Global Effort to Improve Outcomes in Necrotizing Soft Tissue Infections with the SnapNSTI
Be part of an internatio…
Oct 18, 2025 · 8 shares · 3,467 followersView post →
A
AECUrg
@StcuaeC · X
RT @AMGC_Surg: Join the Global Effort to Improve Outcomes in Necrotizing Soft Tissue Infections with the SnapNSTI
Be part of an internatio…
Oct 18, 2025 · 8 shares · 2,355 followersView post →
AS
Ana González, MD, PhD, FEBS Em Surg
@AMGC_Surg · X
Join the Global Effort to Improve Outcomes in Necrotizing Soft Tissue Infections with the SnapNSTI
Be part of an international multicenter study aiming to redefine how we diagnose and treat this life-threatening condition!
link to join:
https://t.co/scsi1E35Uo https://t.co/Rmza17Pm0S
Oct 18, 2025 · 11 likes · 8 shares · 651 followersView post →
A Review published in Critical Care offers clinicians a pragmatic, stepwise approach to antibiotic therapy in necrotizing soft tissue infections, while identifying critical knowledge gaps and priorities for future research.
#MedSky
@SOMELaguna The effectiveness of antibiotic therapy in managing necrotizing soft tissue infections is an urgent topic, especially when considering resistant bacterial strains. How is the current research advancing our understanding, and what gaps still exist in the treatment protocols?
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 13, 2025 · 85 shares · 77 followersView post →
A
Aurora
@AuroraID_ · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 13, 2025 · 85 shares · 81 followersView post →
CJ
Christopher A Jankowski
@StewardshipJAX · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 13, 2025 · 85 shares · 702 followersView post →
K
khameleon40
@Roberto84662649 · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 13, 2025 · 85 shares · 104 followersView post →
SS
Siddhant Shetty
@Dr_ShettyID · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 13, 2025 · 85 shares · 1,379 followersView post →
オ
オスマンサス
@m7gHlB052w3153 · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 12, 2025 · 85 shares · 43 followersView post →
HE
Haitham ElMaleh
@hmalmaleh · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 12, 2025 · 85 shares · 147 followersView post →
DR
David Ricoy
@David_Ricoy · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 12, 2025 · 85 shares · 364 followersView post →
MS
Mario Suárez
@Mariosm148 · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 12, 2025 · 85 shares · 71 followersView post →
P
PROAZA
@PROAZAMORA · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 12, 2025 · 85 shares · 327 followersView post →
FG
Francisco Mora Gómez
@Francis36826302 · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 12, 2025 · 85 shares · 321 followersView post →
MC
Ma.Semiglia Chong
@AuxiSemiglia · X
RT @AliSMV7: Antibiotic therapy in necrotizing soft tissue infections: a narrative review of the greater Paris SURFAST consortium
https://…
Oct 12, 2025 · 85 shares · 217 followersView post →
CS
chrisoh1.bsky.social
@chrisoh1.bsky.social · Bluesky
#OTILT In a retrospective, single center study, empiric vancomycin and clindamycin or linezolid were used to study the duration of therapy for necrotizing soft tissue infections. The study found empiric linezolid for NSTI was associated with one less day of therapy compared to vanco and clindamycin.
#IDSky What do you use as an empiric therapy for necrotizing soft tissue infections (fasciitis)? Please elaborate why.
@empiricgame.bsky.social
@dralicehan.bsky.social
@absteward.bsky.social
@abstewardess.bsky.social
@antibioticdoc.bsky.social
@bradspellberg.bsky.social
With climate change and increased storms:
"Increased awareness of fungi as a cause of necrotizing soft-tissue infections after a natural disaster is warranted"
www.nejm.org/doi/full/10....
Evolution of necrotizing fasciitis or myonecrosis
⭐ Around 50% of cases caused by group A streptococcus occurs without a portal of entry, often initiates deep in the soft tissues at sites of nonpenetrating trauma (e.g. muscle strain or bruise)
https://t.co/RVLj6i4bnm https://t.co/bmeebyusNh
RT @TakaMatsuo_ID: 【Factors Conferring a Predisposition to Specific Necrotizing Soft-Tissue Infections】NEJM 2017
Jun 18, 2024 · 11 shares · 414 followersView post →
K
komteck
@yPHBXIl72vEV82S · X
RT @nagano_1123: 今日のケースカンファの症例がこのreviewのまさに「Invasive Group A Streptococcal Soft-Tissue infection」だった。皮膚に侵入門戸がなくても咽頭などから菌血症→深部より静脈/動脈閉塞→徐々に浅…
Dec 14, 2023 · 7 shares · 811 followersView post →
ア
アタラックスP
@roadtomd1 · X
RT @nagano_1123: 今日のケースカンファの症例がこのreviewのまさに「Invasive Group A Streptococcal Soft-Tissue infection」だった。皮膚に侵入門戸がなくても咽頭などから菌血症→深部より静脈/動脈閉塞→徐々に浅…
Dec 14, 2023 · 7 shares · 1,170 followersView post →
み
みや
@1ch1go1ch1e · X
RT @nagano_1123: 今日のケースカンファの症例がこのreviewのまさに「Invasive Group A Streptococcal Soft-Tissue infection」だった。皮膚に侵入門戸がなくても咽頭などから菌血症→深部より静脈/動脈閉塞→徐々に浅…
Dec 14, 2023 · 7 shares · 3,560 followersView post →
感
感染少尉
@racketandmd · X
RT @nagano_1123: 今日のケースカンファの症例がこのreviewのまさに「Invasive Group A Streptococcal Soft-Tissue infection」だった。皮膚に侵入門戸がなくても咽頭などから菌血症→深部より静脈/動脈閉塞→徐々に浅…
Dec 14, 2023 · 7 shares · 181 followersView post →
M
moleskine
@moleskine8 · X
RT @nagano_1123: 今日のケースカンファの症例がこのreviewのまさに「Invasive Group A Streptococcal Soft-Tissue infection」だった。皮膚に侵入門戸がなくても咽頭などから菌血症→深部より静脈/動脈閉塞→徐々に浅…
Dec 14, 2023 · 7 shares · 521 followersView post →
H
HN
@nagano_1123 · X
今日のケースカンファの症例がこのreviewのまさに「Invasive Group A Streptococcal Soft-Tissue infection」だった。皮膚に侵入門戸がなくても咽頭などから菌血症→深部より静脈/動脈閉塞→徐々に浅部ってあるのね。勉強になりました。
https://t.co/6USw0SjRHK
Dec 14, 2023 · 52 likes · 7 shares · 5,359 followersView post →
AA
Arturo Aleman
@ElArturoAleman · X
RT @ATSCritCare: Check out nice chart about the common pitfalls to diagnosing necrotizing soft tissue infections. #ICU
https://t.co/v2FaBTA…
Dec 10, 2023 · 7 shares · 413 followersView post →
W
weststop
@savegaze · X
RT @NEJM: Review Article: Evolution of Necrotizing Fasciitis or Myonecrosis https://t.co/x9vuiBE9Ed #surgery https://t.co/BC4vDHW7do
Oct 11, 2023 · 137 shares · 462 followersView post →
Aug 31, 2020 · 5 likes · 1 share · 14,301 followersView post →
TM
Tara Moriarty
@moriartylab.bsky.social · Bluesky
Host Genetic Variations and Sex Differences Potentiate Predisposition, Severity, and Outcomes of Group A Streptococcus-Mediated Necrotizing Soft Tissue Infections https://iai.asm.org/content/84/2/416
Melanie Coathup - Musculoskeletal Infection-Springer (2022) | PDF ...
News
2253-2265, https://doi.org/10.1056/NEJMra1600673 (2017). 29. Bonne, S. L. & Kadri, S. S. Evaluation and Management of Necrotizing Soft Tissue Infections ...
Disponible en: 10.1056/NEJMra1600673 25. Gozal D, Ziser A, Shupak A, et al. Necrotizing fasciitis. Arch Surg [Internet]. 1986; [citado el 28 de julio de ...
https://doi.org/10.1056/NEJMra1600673. Stevens, D. L., Bryant, A. E., & Yan, S. S. (2009). Necrotizing soft-tissue infections. New England Journal of ...
08 PPCH 2 2023 Sajad Powiez ENG FINAL | PDF | Health Sciences ...
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doi: 10.1056/NEJMra1600673. 2021; 49(1): 135–144. doi: 10.1007/s15010-020-01559-5. 7. Rajan S.: Skin and soft-tissue infections: classifying and treating a ...
https://doi.org/10.1056/NEJMra1600673. [3] Giuliano A, Lewis F, Hadley K, Blaisdell FW. Bacteriology of necrotizing fas- Although the majority of documented ...