January 2018 PMID 29326244

Gene therapy comes of age.

Cynthia E Dunbar, Katherine A High, J Keith Joung, Donald B Kohn, Keiya Ozawa, Michel Sadelain

Mentions

21
Peak: 3 in Jan 2018
across 5 sources since Apr 2014

Extended reach

33,578
potential audience

Total likes

114

Video views

3,998

Mentions per month

Apr 2014 – Sep 2025

Where it's discussed

  • Facebook9 posts
  • News6 articles
  • X / Twitter3 posts
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

Discussions reflect strong support for the article, with posts emphasizing the breakthroughs in treating diverse conditions like blindness and neuromuscular diseases, and some mentioning revolutionary techniques like genome editing, which underscores the perceived high impact and serious interest in the subject.

AgreementModerate agreement

Most posts acknowledge and support the positive developments in gene therapy, highlighting clinical benefits across various diseases.

InterestHigh interest

Discussions show high curiosity and enthusiasm about the advancements, mentioning specific conditions like blindness and spinal muscular atrophy.

EngagementModerate engagement

Posts analyze technological aspects, such as genome editing and viral vectors, indicating a moderate level of deep engagement.

ImpactHigh impact

The focus on clinical successes and future potential suggests that users see gene therapy as having a significant influence on medicine and patient outcomes.

Abstract in brief

  • Gene therapy has been promising for nearly 30 years but faced setbacks, and now it is becoming an important treatment option for many diseases.
  • Recent advances include approved gene therapies for inherited immune disorders, hemophilia, eye and neurodegenerative diseases, and certain cancers, mainly in the US and Europe.
  • New technologies like genome editing are expected to improve and expand gene therapy options, with methods such as in vivo viral vector delivery and adoptive cell transfer being key focuses.]

Top posts

Most liked on X and Bluesky
Simboke Sarah
@SimbokeSarah · X

Gene therapy comes of age | Science Gene therapy in various forms has produced clinical benefits in patients with blindness, neuromuscular disease, hemophilia, immunodeficiencies, and cancer. https://t.co/7IXpaTVmRv

Sep 18, 2025 · 6 likes · 27,475 followers View post →
Benjamin Solomon
@BenjaminSolomo2 · X

Q366 answer: Spinal muscular atrophy https://t.co/0eaIfDdRk5 https://t.co/lzOamcCICk https://t.co/q6dR61SIC2

Oct 26, 2021 · 1 like · 1,911 followers View post →
Isatou Sarr
@IsatouSarr4 · X

Gene therapy comes of age https://t.co/ehxv9BFZ30

Nov 12, 2021 · 1 like · 45 followers View post →
Ed Yong
@edyong209.bsky.social · Bluesky

(In mice) RT @RomiSphinX: GeneTherapy comes of age: We can now edit entire genomes to cure diseases http://www.extremetech.com/extreme/179536-gene-therapy-comes-of-age-we-can-now-edit-entire-genomes-to-cure-diseases

Apr 1, 2014 View post →

All mentions

Simboke Sarah
@SimbokeSarah · X

Gene therapy comes of age | Science Gene therapy in various forms has produced clinical benefits in patients with blindness, neuromuscular disease, hemophilia, immunodeficiencies, and cancer. https://t.co/7IXpaTVmRv

Sep 18, 2025 · 6 likes · 27,475 followers View post →
Isatou Sarr
@IsatouSarr4 · X

Gene therapy comes of age https://t.co/ehxv9BFZ30

Nov 12, 2021 · 1 like · 45 followers View post →
Benjamin Solomon
@BenjaminSolomo2 · X

Q366 answer: Spinal muscular atrophy https://t.co/0eaIfDdRk5 https://t.co/lzOamcCICk https://t.co/q6dR61SIC2

Oct 26, 2021 · 1 like · 1,911 followers View post →
Ed Yong
@edyong209.bsky.social · Bluesky

(In mice) RT @RomiSphinX: GeneTherapy comes of age: We can now edit entire genomes to cure diseases http://www.extremetech.com/extreme/179536-gene-therapy-comes-of-age-we-can-now-edit-entire-genomes-to-cure-diseases

Apr 1, 2014 View post →
The amazing Bio lab
Facebook

Science - https://doi. org/10.1126/science.aan4672 (5) Viral vectors in gene therapy: Opportunities and challenges. Advances in Virus Research - https://doi ...

Dec 17, 2025 View →
[NHỮNG CHỦNG VI SINH VẬT TỒN TẠI Ở... - The amazing Bio lab ...
Facebook

Science - https://doi. org/10.1126/science.aan4672 (5) Viral vectors in gene therapy: Opportunities and challenges. Advances in Virus Research - https ...

Dec 17, 2025 View →
Gene therapy comes of age | Science
News

Science. 12 Jan 2018. Vol 359, Issue 6372. DOI: 10.1126/science.aan4672 · PREVIOUS ARTICLE. Mapping the malaria parasite druggable genome by using in vitro ...

Dec 17, 2025 View →
Here Are Some Credible References You Can Use For Gene ...
News

Gene therapy comes of age. Science, 359(6372), eaan4672. https://doi.org/10.1126/science.aan4672. o Discusses clinical applications and recent FDA ...

Dec 17, 2025 View →
Industrial Applications of Microbes and Viruses in Biotechnology
News

(2018). Gene therapy comes of age. Science, 359(6372), eaan4672. DOI: 10.1126/science.aan4672; Newman, D.J., & Cragg, G.M. (2020). Natural ...

Nov 22, 2024 View →
[VIRAL VECTOR - ĐỘT PHÁ TRONG CÔNG NGHỆ GEN] Vector ...
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... Science - https://doi.org/10.1126/science.aan4672 (5) Viral vectors in gene therapy: Opportunities and challenges. Advances in Virus ...

Sep 29, 2024 View →
The amazing - Chi nấm Penicillium Thuộc một giới sinh vật riêng ...
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Science - https://doi. org/10.1126/science.aan4672 (5) Viral vectors in gene therapy: Opportunities and challenges. Advances in Virus ...

Sep 8, 2024 View →
The amazing - CƠ CHẾ HOẠT ĐỘNG ✍️ Tổng hợp Chuỗi DNA ...
Facebook

Science - https://doi. org/10.1126/science.aan4672 (5) Viral vectors in gene therapy: Opportunities and challenges. Advances in Virus ...

Aug 31, 2024 View →
The amazing Bio lab added a new photo. - The amazing ... - Facebook
Facebook

Science - https://doi. org/10.1126/science.aan4672 (5) Viral vectors in gene therapy: Opportunities and challenges. Advances in Virus ...

Jul 3, 2024 View →
Deep Involvement, Pattern Recognition, Community ... - Facebook
Facebook

... Science 337: 816–821. CAS PubMed PubMed ... 10.1126/science.aaf8729. Qi, L.S., et al ... aan4672. Baltimore, D. et al. 2015 ...

May 11, 2022 View →
هكمل فى فيديو جديد | Facebook
Facebook

Biotech Pioneers▻Biology and Science. Aug 8, 2023 ... science.org/doi/full/10.1126/science. aan4672 https://www.nature.com/articles/35038533.

Nov 1, 2021 View →
"يَخْرُجُ مِنْهُمَا اللُّؤْلُؤُ وَالْمَرْجَانُ (22) فَبِأَيِّ آلَاءِ رَبِّكُمَا تُكَذِّبَانِ (23)."♥️
Facebook

Biology and Science. Biotech Pioneers

Oct 25, 2021 View →
Gene therapy moves from promise to reality | MDedge
News

doi: 10.1126/science.aan4672). “We really felt it was the right time to write the article,” she said. Milestones. A new approach ...

Jan 25, 2018 View →
The coming of age of gene therapy: A review of the past and path ...
News

Science, 12 Jan 2018 DOI: 10.1126/science.aan4672. Cite This Page: MLA; APA; Chicago. NIH/National Heart, Lung and Blood Institute. "The coming ...

Jan 15, 2018 View →
CONTENTS
News

C. E. Dunbar et al. REVIEW SUMMARY; FOR FULL TEXT: dx.doi.org/10.1126/science.aan4672. RESEARCH ARTICLES. 176 PROTEIN MODIFICATION. Fatty acyl ...

Jan 12, 2018 View →