BMC Biol January 2018 PMID 29338710

A genetically encoded Ca indicator based on circularly permutated sea anemone red fluorescent protein eqFP578.

Yi Shen, Hod Dana, Ahmed S Abdelfattah, Ronak Patel, Jamien Shea, Rosana S Molina, Bijal Rawal, Vladimir Rancic, Yu-Fen Chang, Lanshi Wu, Yingche Chen, Yong Qian, Matthew D Wiens, Nathan Hambleton, Klaus Ballanyi

Mentions

3
Peak: 1 in May 2019
across 2 sources since May 2019

Extended reach

252,382
potential audience

Total likes

4,583

Video views

243,380

Mentions per month

May 2019 – Mar 2024

Where it's discussed

  • YouTube2 videos
  • X / Twitter1 posts

AI synopsis

What people are saying

The discussions reflect a generally positive attitude, with phrases like 'missed it,' indicating curiosity and recognition of the publication's importance, and mentions of the genetically encoded calcium indicator's advantages, implying anticipation of future research benefits.

AgreementModerate agreement

Most discussions acknowledge the significance of the research, with some expressing enthusiasm about its potential improvements.

InterestModerate interest

Participants show moderate interest, mentioning the technological advancements and potential applications.

EngagementModerate engagement

Comments include references to the methodological aspects and implications, indicating active engagement.

ImpactModerate impact

The conversations suggest an optimistic view of the publication's potential influence in neuroscience and cellular imaging.

Abstract in brief

  • This text discusses a new genetically encoded calcium indicator (GECI) called KGECO1, made from a red fluorescent protein derived from sea anemone, which helps scientists track calcium activity in cells for neuroscience research.
  • KGECO1 offers advantages like deeper tissue imaging and multicolor options due to its red fluorescence, with performance already comparable or better than existing GECIs, and it works well in different cell types and live animal models.
  • Future improvements could make KGECO1 even more effective, potentially surpassing current top red GECIs by reducing issues like lysosomal buildup and enhancing sensitivity and kinetics.]

Top posts

Most liked on X and Bluesky
BMC Biology
@BMCBiology · X

In case you missed it: A genetically encoded Ca2+ indicator based on circularly permutated sea anemone red fluorescent protein eqFP578 https://t.co/WV5ZJ2cBYq

May 7, 2019 · 9,003 followers View post →

All mentions

BMC Biology
@BMCBiology · X

In case you missed it: A genetically encoded Ca2+ indicator based on circularly permutated sea anemone red fluorescent protein eqFP578 https://t.co/WV5ZJ2cBYq

May 7, 2019 · 9,003 followers View post →