PubHawk
Anesthesiology August 2018 PMID 29462012

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain.

Ru-Rong Ji, Andrea Nackley, Yul Huh, Niccolò Terrando, William Maixner

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Mentions

77
Peak: 25 in Jun 2020
across 5 sources since Jan 2019

Extended reach

498,916
potential audience

Total likes

130

Video views

674

Mentions per month

Jan 2019 – Jan 2023

Where it's discussed

  • X / Twitter46 posts
  • News17 articles
  • Facebook10 posts
  • YouTube2 videos
  • Blogs2 articles

AI synopsis

What people are saying

Discussions emphasize the scientific significance of neuroinflammation in chronic pain, with references to key concepts like central sensitization and glial cell activation, highlighting the article’s potential to inform future treatments. The tone varies from supportive acknowledgment to curiosity about mechanisms, reflecting both respect for the research and hope for clinical advances.

AgreementModerate agreement

Most posts acknowledge the significance of neuroinflammation and central sensitization in chronic pain, with some highlighting the research's importance and relevance.

InterestHigh interest

Discussions show high interest, referencing specific mechanisms, clinical examples, and notable research citations.

EngagementModerate engagement

Some posts engage deeply by mentioning neuroimmune mechanisms and potential treatment implications, though others are more general.

ImpactModerate impact

There is a perception that the research might influence the understanding and treatment of chronic pain, though the impact is mostly implied rather than directly stated.

Abstract in brief

  • Chronic pain is partly sustained by central sensitization, a change in the nervous system that makes it more responsive to pain after injury or harmful stimuli.
  • Neuroinflammation, involving activation of glial cells like microglia and astrocytes in the brain and spinal cord, releases inflammatory molecules that contribute to this increased pain sensitivity and can lead to widespread, chronic pain.
  • The article highlights the importance of neuroinflammation in chronic pain, notes sex differences in immune responses, and discusses new treatments targeting neuroinflammation to help resolve persistent pain conditions.]
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Top posts

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Derek Griffin
@DerekGriffin86 · X

The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://t.co/uJXUvobAi7

Jun 16, 2020 · 83 likes · 27 shares · 38,422 followers View post →
Duke Anesthesiology
@Duke_Anesthesia · X

Jul 9, 2021 · 15 likes · 4 shares · 14,324 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain https://t.co/qDKleTzHDH https://t.co/kRGNb7zloW

May 6, 2021 · 10 likes · 2 shares · 133,615 followers View post →
ASA®
@ASALifeline · X

Highly cited @ALNanesthesia research on “Neuroinflammation and Central Sensitization in Chronic and Widespread Pain” receives #trophy status by @webofscience. Read the full study: https://t.co/pSkubxB0N5

Mar 15, 2019 · 3 likes · 4 shares · 37,520 followers View post →
Leonardo Rodríguez Lagos
@leo_rodriguezl · X

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain. - PubMed - NCBI https://t.co/xLsKw0rONc

Apr 15, 2019 · 2 likes · 194 followers View post →
Alejandro ruiz barrios
@Ruizbarrios27 · X

@RoyLaTouche El dolor crónico estará mantenido en parte por la sensibilización central, ya que también es impulsada por la neuroimflamación en el sistema nervioso periférico y central. https://t.co/lMrzRNfWCe #fisioCoglasalle

Jan 5, 2023 · 1 like · 2 followers View post →

All mentions

Hi2u
@RETsetLife · X

Neuroinflammation and central sensitization in chronic and widespread pain ➡️https://t.co/VfNBvrwQrQ

Jan 31, 2023 · 417 followers View post →
Alejandro ruiz barrios
@Ruizbarrios27 · X

@RoyLaTouche El dolor crónico estará mantenido en parte por la sensibilización central, ya que también es impulsada por la neuroimflamación en el sistema nervioso periférico y central. https://t.co/lMrzRNfWCe #fisioCoglasalle

Jan 5, 2023 · 1 like · 2 followers View post →
Dr._Rex
@Dr_Rexc · X

RT @Duke_Anesthesia:

Jul 9, 2021 · 4 shares · 53 followers View post →
Yousef AlMassalmeh
@ymassalmeh · X

RT @Duke_Anesthesia:

Jul 9, 2021 · 4 shares · 77 followers View post →
Anesthesiology Journals
@_Anesthesiology · X

RT @Duke_Anesthesia:

Jul 9, 2021 · 4 shares · 38,319 followers View post →
Plexus TG & Plexus MG
@PlexusTechGroup · X

RT @Duke_Anesthesia:

Jul 9, 2021 · 4 shares · 36 followers View post →
Duke Anesthesiology
@Duke_Anesthesia · X

Jul 9, 2021 · 15 likes · 4 shares · 14,324 followers View post →
Maitreya
@Mithreu · X

RT @Grimhood: Neuroinflammation and Central Sensitization in Chronic and Widespread Pain https://t.co/qDKleTzHDH https://t.co/kRGNb7zloW

Jun 14, 2021 · 2 shares · 1,259 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

RT @Grimhood: Neuroinflammation and Central Sensitization in Chronic and Widespread Pain https://t.co/qDKleTzHDH https://t.co/kRGNb7zloW

Jun 13, 2021 · 2 shares · 133,615 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain https://t.co/qDKleTzHDH https://t.co/kRGNb7zloW

May 6, 2021 · 10 likes · 2 shares · 133,615 followers View post →
My Spine Relief
@myspinerelief · X

Neuroinflammation and central sensitization in chronic and widespread pain #sciaticnerve https://t.co/KAhLgNZhlb

Apr 28, 2021 · 10 followers View post →
Jeffrey Bone
@DrJeffreyBone · X

Neuroinflammation and central sensitization in chronic and widespread pain https://t.co/jiRF9qgRsq

Jan 3, 2021 · 733 followers View post →
/r/Neuroscience
@neuroreddit · X

Neuroinflammation and central sensitization in chronic and widespread pain https://t.co/gWjN1hN0zY

Jan 3, 2021 · 6 followers View post →
My Spine Relief
@myspinerelief · X

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain #backpain https://t.co/KSRYW5bQvF

Dec 13, 2020 · 10 followers View post →
FILM.PHYSIO
@FilmPhysio · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 24, 2020 · 27 shares · 19 followers View post →
Ina Diener
@InaDiener · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 20, 2020 · 27 shares · 898 followers View post →
Ander Zulet
@AnderZulet · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 18, 2020 · 27 shares · 1,179 followers View post →
LucaMarson
@LucaMarson5 · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 17, 2020 · 27 shares · 15 followers View post →
Madhan Ramanathan
@sportsphysiouk · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 17, 2020 · 27 shares · 1,148 followers View post →
Mark Overton
@MarkOvertonPT · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 17, 2020 · 27 shares · 100 followers View post →
Jaro Karppinen
@jaro_karppinen · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 17, 2020 · 27 shares · 465 followers View post →
Firmansyah Purwanto
@MovementPainPT · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 1,293 followers View post →
Javier Herraiz Fisio
@JavierHerraiz3 · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 901 followers View post →
AMP
@AMP_Physio · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 3,887 followers View post →
MVClinic Institute
@MVClinic · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 3,244 followers View post →
panagiotis griveas
@PGriveas · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 45 followers View post →
Carlos Chiza
@ChizaCarlos · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 63 followers View post →
Andrew Pontin
@PontinAndrew · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 292 followers View post →
Mosiah Araújo Silva
@MosiahAraujo · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 69 followers View post →
Liz Monserrath Ortiz
@LizMonserrath · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 33 followers View post →
addingham physio
@PhysioAddingham · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 18 followers View post →
Leonardo Rodríguez Lagos
@leo_rodriguezl · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 194 followers View post →
Theresa Rogan
@TrojanSA · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 250 followers View post →
Jordi Aridane
@JordiAridane · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 491 followers View post →
ɹǝʇlnoԀ pıʌɐᗡ
@Retlouping · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 26,355 followers View post →
Virginia Rivers Bulkeley
@BulkeleyV · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 984 followers View post →
ACPSEMdance
@ACPSEMdance · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 2,969 followers View post →
Adam Dobson
@adamdobson123 · X

RT @DerekGriffin86: The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://…

Jun 16, 2020 · 27 shares · 12,650 followers View post →
Derek Griffin
@DerekGriffin86 · X

The neuroimmune mechanisms that may predispose to the development of persistent pain. https://t.co/MqV2MNSHcG https://t.co/uJXUvobAi7

Jun 16, 2020 · 83 likes · 27 shares · 38,422 followers View post →
Leonardo Rodríguez Lagos
@leo_rodriguezl · X

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain. - PubMed - NCBI https://t.co/xLsKw0rONc

Apr 15, 2019 · 2 likes · 194 followers View post →
Lic. Jorge Saborido
@KinePain · X

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain. - https://t.co/Jt31wjplRl

Apr 15, 2019 · 407 followers View post →
Allan F. Simpao, MD, MBI
@asimpao · X

RT @ASALifeline: Highly cited @ALNanesthesia research on “Neuroinflammation and Central Sensitization in Chronic and Widespread Pain” recei…

Mar 19, 2019 · 4 shares · 1,267 followers View post →
Anesthesiology Journals
@_Anesthesiology · X

RT @ASALifeline: Highly cited @ALNanesthesia research on “Neuroinflammation and Central Sensitization in Chronic and Widespread Pain” recei…

Mar 19, 2019 · 4 shares · 38,319 followers View post →
Theresa McGeary Hill
@theresamcghill · X

RT @ASALifeline: Highly cited @ALNanesthesia research on “Neuroinflammation and Central Sensitization in Chronic and Widespread Pain” recei…

Mar 18, 2019 · 4 shares · 417 followers View post →
ASA®
@ASALifeline · X

Highly cited @ALNanesthesia research on “Neuroinflammation and Central Sensitization in Chronic and Widespread Pain” receives #trophy status by @webofscience. Read the full study: https://t.co/pSkubxB0N5

Mar 15, 2019 · 3 likes · 4 shares · 37,520 followers View post →
painmanwise
@painmanwise · X

Neuroinflammation and Central Sensitization in Chronic and Widespread Pain. https://t.co/oXbbLrpgh7

Jan 10, 2019 · 225 followers View post →