Anesthesiology June 2018 PMID 29489470

Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndrome.

Raquel S Santos, Ligia de A Maia, Milena V Oliveira, Cíntia L Santos, Lillian Moraes, Eliete F Pinto, Cynthia Dos S Samary, Joana A Machado, Anna Carolinna Carvalho, Marcos Vinícius de S Fernandes, Vanessa Martins, Vera L Capelozzi, Marcelo M Morales, Thea Koch, Marcelo Gama de Abreu

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Mentions

8
Peak: 1 in May 2018
across 3 sources since May 2018

Extended reach

15,482
potential audience

Total likes

100

Video views

13,097

Mentions per month

May 2018 – Apr 2020

Where it's discussed

  • Facebook5 posts
  • X / Twitter2 posts
  • YouTube1 videos

AI synopsis

What people are saying

The discussions reflect a cautious perspective on the study, exemplified by comments like welcoming health innovation but warning against using overly simple ventilators without feedback mechanisms. The tone is somewhat skeptical and focused on practical implications, indicating moderate interest and engagement without deep analysis, and a recognition that the research could influence ventilator design or clinical practice in future.

AgreementNeither agree nor disagree

The discussion shows mixed opinions; one post welcomes innovation cautiously, while another is more critical of simple ventilator use.

InterestModerate interest

The social discussions indicate some curiosity about the research, but without deep engagement or detailed analysis.

EngagementModerate engagement

Participants demonstrate a basic level of engagement, mentioning innovations and potential impacts, but without detailed critique or exploration.

ImpactNeutral impact

Overall, the posts suggest a recognition of the importance of the findings but do not convey a consensus on their significance or application.

Abstract in brief

  • The study investigated how different combinations of tidal volume (VT) and respiratory rate (RR), which together determine mechanical power, affect lung injury in rats with mild ARDS, showing that higher power worsens injury regardless of VT.
  • Results indicated that high mechanical power, especially at high VT, increased lung damage, inflammation (like interleukin-6), and related molecular markers, compared to low power settings.
  • The authors suggest that to prevent ventilator-induced lung injury, it’s important to use low tidal volumes in combination with low mechanical power during mechanical ventilation.]

Top posts

Most liked on X and Bluesky
Dr Kaye Rolls
@kaye_rolls · X

@anaximandus @WIRED here is a video https://t.co/bRmJhwUr7V #VALI I welcome innovation in health however use of very simple ventilators without feedback or customisation will lead to sicker pts

Apr 3, 2020 · 2,296 followers View post →
Juan Rueda
@juanruedag · X

RT @SleepyExperts: Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndro…

Feb 9, 2020 · 1 share · 88 followers View post →

All mentions

Dr Kaye Rolls
@kaye_rolls · X

@anaximandus @WIRED here is a video https://t.co/bRmJhwUr7V #VALI I welcome innovation in health however use of very simple ventilators without feedback or customisation will lead to sicker pts

Apr 3, 2020 · 2,296 followers View post →
Juan Rueda
@juanruedag · X

RT @SleepyExperts: Biologic Impact of Mechanical Power at High and Low Tidal Volumes in Experimental Mild Acute Respiratory Distress Syndro…

Feb 9, 2020 · 1 share · 88 followers View post →